Conserved Protein Domain Family
Cas10d_I-D
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cd09712: Cas10d_I-D 
CRISPR/Cas system-associated protein Cas10d
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain. Fused to N-terminal HD domain; signature gene for I-D subtype; also known as Csc3 family
Links
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Statistics
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PSSM-Id: 187843
Aligned: 4 rows
Threshold Bit Score: 1110.74
Created: 6-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
NP_942299   73 KGDQTLAAHILNALLTTWNV----MQELEFP----LNDIERR--LLCLGITLHDYDKHchaqdmAAPEPD-NIQEIINIC 141  Synechocystis sp...
YP_324664   93 AADQSLNTHLLNGLFPANLIer-rLQQLDTTv--rRVVKERErrLVIAGFILHDFEKFpd---vPNDCRKlPLAEHRPII 166  Anabaena variabi...
YP_503300   62 KTDQPMINHVRNGIQALIELnktlLQSGSAHy---LPVSKLR--EVIALFSIHDLHKTig--kdWRDQFDlNEDEVMSFA 134  Methanospirillum...
YP_327279   90 KVDQSMLNHTRNLVYFLHQL----ARQIENTdlpsITPKKLR--HLVALAVAHDYHKLreedenPNERFDiKIKELEPFI 163  Natronomonas pha...

NP_942299  142 LElgkrLNFDEFWa------------DWRDYIAEisylaqnTHGKQHTNLISSNWSNagypftikerkldhpLRHLLTFG 209  Synechocystis sp...
YP_324664  167 DAkirqLGLDKFInpense-ayqeyiDDLLCMAYn------AQSRWDTNWNFSEFGLnpvlrd----rtlrqLSGLTLLA 235  Anabaena variabi...
YP_503300  135 HA----IQADIFApal-------tpnDFLSVAVA-------THPTQGFHGDLSHTFIt--------------YKNWVLLA 182  Methanospirillum...
YP_327279  164 EE----IGLDEFSstpddpeselsirTFRSCAVD-------HHDTENANSTRVTTTWr-------------eYRPLIRLA 219  Natronomonas pha...

NP_942299  210 DVAVHL-SSPHDlvsSTMGDRLRDLlnrlgIEKRFv--YHHLRDTTGILSNAIHNVILRt-----vQKLDWK--PLLFFA 279  Synechocystis sp...
YP_324664  236 DSLASIvKHPQDaehSKLKEVLHFLsd--gQLKLT---YHSIAENRGVLTNVVNNALIQahtslntDEHTYYe-PLLYLP 309  Anabaena variabi...
YP_503300  183 DIFASL-EMPVVt--EGMKKHIAFId----AKKTFf--YHTFSESIGLLSNVVHAAVLE-------WAKQYAlfPLLFFE 246  Methanospirillum...
YP_327279  220 DSMASS-ATPEAatnNRVQDRFREAf----PSGNFelaYHQTDHVSGVFTNLLNKVVSEyl----qEEYDYQ--LLTMYQ 288  Natronomonas pha...

NP_942299  280 QGVIYFAPQDTEIPERNEikqIVWQGISQELGKKMSAGDVGFKR-----------DGKGLKVSPQTSELLAAADIVRILP 348  Synechocystis sp...
YP_324664  310 TGVIYLAARHAPPISTEDlpdRVVDNIKSLCAGQLRLRQTGFGR-----------DGKGMKYAEYYNLFFESPGLMQVAL 378  Anabaena variabi...
YP_503300  247 KGVIYLGDKNSRFEFTQA---SQIEEIYQELKKKIQSSHESLSRpeklqkyiqvqGSKGLFSVEESFFFYSGIHTVIKAF 323  Methanospirillum...
YP_327279  289 DGCVYLTPAELDQPETDE---DIVAAITSRLGDSIGDSHPSYNDidqlrsnfsivGAQGLYSLNEPDFFYAGSGKMLQAV 365  Natronomonas pha...

NP_942299  349 QVISVKVNNAKSPAT---PKRLEKL------ELGDAEREKLYEVadl----------------------------rcDRL 391  Synechocystis sp...
YP_324664  379 DATLRILNPNKDSVA---KSRSENLikfqqqGVLCADYDFKFDDdi-----------------------------riDQI 426  Anabaena variabi...
YP_503300  324 LAAAVMTSEKDNSGNfeiDTSTPSL------TLNKSDLEMQYPPaevidvpahfiksisvdgnvipvsdvriichgeERK 397  Methanospirillum...
YP_327279  366 VRKGVTDGDADASAT---DAATESM------ELLEAELGTKFEKt--------------------------------EQQ 404  Natronomonas pha...

NP_942299  392 AELLGLVQ---------------------------------------KEIFLl--------------------------- 405  Synechocystis sp...
YP_324664  427 AEFGDLVSr--------------------------------------KIWDEtvnrie------------------dirk 450  Anabaena variabi...
YP_503300  398 AKKYTLVPdsvfvgeeeifglititgiglmpsmvgyrshilsdfgvdTGWDEsiiplaravsgirkdvitelikagslpt 477  Methanospirillum...
YP_327279  405 YGLGRFVNt-------------------------------------iKSWFV---------------------------- 419  Natronomonas pha...

NP_942299  406 pEPFIE---------------WVLKDLELTSVI---MPEETQVQ-----SGGVNYGWYRVAAHYVANH-----ATWDLEE 457  Synechocystis sp...
YP_324664  451 kDKKLPavpaldl-thkvaefWNLTAYLPQIREiqhINESLKENklkgnTGGVPYEWYYLAAKYLEHHp---gIESVRET 526  Anabaena variabi...
YP_503300  478 dDPLLEac-----------rmFQTNDDLTQKMVt--YASENRGQdh-hsVGGFWNYSYAIARDILDREvn-giAFSQIAS 542  Methanospirillum...
YP_327279  420 -DPLLPsdrtandliratvtaFGLSDELAEDLVa--LSEETTSAl---tSGGKWEYSYAIAQGLLDRHgtgpvIPTVEDE 493  Natronomonas pha...

NP_942299  458 FQEFLQGFgdrla------twaeeEGYFAEHQSPTRq----------iFEDYLDRYLEIQGWesd----------hqaFI 511  Synechocystis sp...
YP_324664  527 CQQVIQYF----------------TGLISPIISQYKlp---------dGWDDLRLWVSRVVMlpntnqeasaktqvdtFL 581  Anabaena variabi...
YP_503300  543 IQEKISYLntlvdeylstissenlEKFESAILYPYKe----------kLLVWLCENLSINGSm---------------LY 597  Methanospirillum...
YP_327279  494 IVMTLSDGf--------------aALVEDDSDWQTRiqnahagdmateVQAFIGETLRIGGGnlilt------satvdTY 553  Natronomonas pha...

NP_942299  512 QELENY-VNAKTKks-kqPICSLSSGEFPSEDQMDSv--VLFKPQQYSNKNPLGGGQI-KRGISKIWSLEMLLRQAFWSV 586  Synechocystis sp...
YP_324664  582 AELNNY-NAAKKPgrgkqLICSISHSAYTVTEQMESa--VLFTPQVYTNKQMLGGSNA-KRNISSIAGVEMMLRQILMNQ 657  Anabaena variabi...
YP_503300  598 GSFENKtNKFKAYcd-gtGICRLTNDTPYDKERKTTskdVSMLKYTFSNRVPIGSSEP-SLYVSVPVQIELGLRSIGHGI 675  Methanospirillum...
YP_327279  554 DEYVKS-SRGKTC-----TLCSRGVAVGGNLGPMKSkqsLTTLQGGFSNREMVGGMKRdKLLLCSICRIEFSLRETAASR 627  Natronomonas pha...

NP_942299  587 Psgk---fedQQPIFIYLYPAYVYAPQVVEAIRELVYGIasvnlWDVRKHWVNNKMDl---TSLKSLPW-------LNEE 653  Synechocystis sp...
YP_324664  658 TqavgkrfedGKYRYLYFYPTYYFTPETNKFLQKAYNGIaq-trFDTSVRNHFISKDlqanLEREKYQSvdaflidENLE 736  Anabaena variabi...
YP_503300  676 Rk-------gSDKIYFRLIPDYHFSHTTASIFSQFANYFd----GDSGTRVLDLARE----FLREDVPSeds--iiELLI 738  Methanospirillum...
YP_327279  628 Rd--------GGRLFFHLVPDYFYTPYSWRLYSRLVNRFt----GENRVRLGRLAERvfdiDSLEEFTGvm---deLTQP 692  Natronomonas pha...

NP_942299  654 VEAGTNAQLKYT-----KEDLPFLAt--vYTTTREKtDTDAWVKPAFLALLLPYLLGVKAIATRSMVPlYRSdQDFRESI 726  Synechocystis sp...
YP_324664  737 REKDRTFKLSYPd----DQPLTFYFm--aLPPGRDStDTESWIMPSWLAFAFPMILDVKTVVSESPIPpFNDgAEFEESV 810  Anabaena variabi...
YP_503300  739 AETGRKNICQYAglgffYQNSTFDFv---FNKKRNG-DGEYWFFGSYLALILAYVTGCRVVAGENPIC-MTSgDEFSEFV 813  Methanospirillum...
YP_327279  693 EGNGRTMIESLSqe--fDRNRQFGAqtvgYFKNPDN-DTEFQFFGAFLALTVSAYTGMRVYLSSSPVPeMRS-RDFPEFA 768  Natronomonas pha...

NP_942299  727 HLdGVAGFWSLLGIPTDLRVEDI-----------TPALNKLLAIYTLHLAARssp----pkARWQDLPKTVQEVMTDVLN 791  Synechocystis sp...
YP_324664  811 FLdSAPHAFRALVRRDRFRLDYIlegwddngiqyPAPLNVLTAAYAIHLDVNarqgksgydANWGRFTELAKDFETSPLY 890  Anabaena variabi...
YP_503300  814 LL-EAPHVAVKRIFSDRIRLSDL-----------KKTLMTASLIISMGYEIR---------MDDAAFVRFLQTFRNHPFP 872  Methanospirillum...
YP_327279  769 KI-GSGFTQVTSFYGETVSLTSL-----------QSELQSAAAVVKLGYAIQgn------dRNDSLFAKYLRTTRNELLP 830  Natronomonas pha...

NP_942299  792 VFALAEQGLR---------------REKRd-RPYESEVTEYWQf---AELFSQGNIVMTEKLKLT----------KRLVE 842  Synechocystis sp...
YP_324664  891 VFSYLNRWVR---------------NQGIe-TARIEKIRLYAYh--fYPCFDPYVQYDMDTKTLTvksesslnhpKNLTE 952  Anabaena variabi...
YP_503300  873 GSTLLKQIRRvyeqdkkkggmggfvNSARgwRKVDGEIIRSEY----PGFIFQAVKLDTFGENPMa--------vASIHE 940  Methanospirillum...
YP_327279  831 GSYLLKRAVQ---------------TSDE--GPYIPALMRYAValdqRNAIRQSNSQMTDTPHNRi---------STLAE 884  Natronomonas pha...

NP_942299  843 EYRRFYQVELSKKPSTHAILLPLSKALEQIL-SVPDD-WDEEELILQGSGQLQAALDRQevytrpiikDKSVAYETRQLQ 920  Synechocystis sp...
YP_324664  953 LYRRFYRANKRYNPKSNAVLKPIDIAAETIL-KAESSvFHGETLVVGVAAEVFRLMDRVha-----stAEGRWVMSKREE 1026 Anabaena variabi...
YP_503300  941 LARLGLSVAIPRNYDPHKVEKLFRESVKAILgKRGSQ-YPREDYVDAVSGRLLKMIKRA---------GDDQFSRTPGLY 1010 Methanospirillum...
YP_327279  885 LAYDAIRPASGHGRKPHRVERVFRESVKAVS-KTGQQ-LDQEDYKMCVSGRLQKMIDRQa--------GDAVYPVSAEES 954  Natronomonas pha...

NP_942299  921 El-----EAIQIFMTTCVRDLFGEMCKGDRAILQEQRNRIKSG-AEFAYRLL 966  Synechocystis sp. PCC 6803
YP_324664 1027 Er-----QAVLDFAKYFVIEVFEKAFAGDRARLAGRQLNLIRDtCEFLYRLE 1073 Anabaena variabilis ATCC 29413
YP_503300 1011 Df-----SLIVSFAEYFVDHIFYQVASGDPGKLKRAANDLADGfYSATLQLR 1057 Methanospirillum hungatei JF-1
YP_327279  955 DagtplqERIEEYAAYFVDEILYGIANGRPSQLKRLENNLADGfFGATLRAE 1006 Natronomonas pharaonis DSM 2160
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