Conserved Protein Domain Family
Cas10_III
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cd09701: Cas10_III 
CRISPR/Cas system-associated protein Cas10
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, inactivated palm domain and Zn-ribbon; signature gene for type III
Links
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Statistics
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PSSM-Id: 187832
Aligned: 10 rows
Threshold Bit Score: 846.704
Created: 6-Feb-2010
Updated: 17-Jan-2013
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAB84832        1 MSNIKNIRKRRKEVLLGEIGALLHDIGKLHPNFIGTNSIEKMPprff-------------------hanIDDFLKTELIS 61   Methanothermo...
YP_002465098    1 MNQLDVLAQHREMLLLAEAIGWLHDYRKCSDEQLKVQASNPQGsa-----------------------lPRNALANRYSQ 57   Chloroflexus ...
NP_635380       2 SADLKVLADNKANLLLAEVAAWLHDMGKCSDKFVISSSCDKPSgfeykske----------dylsnfneNNNEIKSIFEN 71   Methanosarcin...
YP_001738355    4 MSILETLKENRTPILLAEIGAYLHLVGRFSKEFLETHVRDSDLqfdyqkicsnsd---ffentrlyemlTNKKLKDFISK 80   Thermotoga sp...
YP_304896       2 SPDLKILADNKKALHLAEIAAWLHDMRKCSDKFLIGNSLDRQLdstekn---------------sevthFLKDIKTRFKK 66   Methanosarcin...
YP_002248916    2 NSLLEKLKNNRTAILLAEIGAYLHLLGRFSKEFIYSNAEDADPncdnfdyqnicndnrffgnfslkdllQNDIWKTYLNK 81   Thermodesulfo...
YP_001470831  258 TMCVEMIKNNREMILIGEICALLHDIGKLHPNFIKTQSVEGIKglph-------------------hsgGIDQLIKAELI 318  Thermotoga le...
YP_002940969    1 MSILKIVEENRVPILLAEIGAYLHDLGKATKDFIEGNSKEAGNqrp---------------------shTPPKLFPDELR 59   Thermotogales...
YP_001276916    2 SYDLNKLVTAQDNLLLAEVAAWVHDWQKCIDMKVASDWNNNPNvnkvki---------------rnwqqRGTTLKPGDFA 66   Roseiflexus s...
YP_002728838    1 MSGLNRIKNNKDEILKAEIVSYLALWEKLNPSKQNRASINIQC--------------------------NNLSCWESALK 54   Sulfurihydrog...

AAB84832       62 ALKAFEDLEINVEPIRIYNIISE---HHRNNVLQG------CDRKDSAD----------DKGIVRR-----KQSITDTVI 117  Methanothermo...
YP_002465098   58 LTGVNLHLPVQAGARTVTNLLDD---STWKNDLLGqy---lSRCHNTAHf---------DKQEPVGg----KQAYPGMQI 118  Chloroflexus ...
NP_635380      72 TFVDFSKVNFINEKVTLNDLIVKglpRTNKEKEKDkfp-wlVRTLGRCHgaa-----hiEKEDSKEf----KQYKNYTMI 141  Methanosarcin...
YP_001738355   81 LNTSAAVEELKKDIDNFCNFIQK---HTWRDAPKGl-----CKILADAHgiv----sgiDKSLAGRiveagKQRKNYIFR 148  Thermotoga sp...
YP_304896      67 IEIDFSEVNPIFEKVTLNKLIEKgrpETLKKENLQkkypwiVKALGRCHgaa-----hiEKENVSEel--fKQYKDYTMI 139  Methanosarcin...
YP_002248916   82 FISDKDLKDLKQNLTTFCDFIKK---HTWTQTPQGl-----CKILADAHgiv----sgiDKALAGRgk-ggKQRKRYTFK 148  Thermodesulfo...
YP_001470831  319 DFFKSIDMKINTESMSIYDSIRFhhdNSTNNILKClk---eCDRKDSAD----------DKGIVRR-----KQHLDSTWI 380  Thermotoga le...
YP_002940969   60 KILSEVKIDVLNEKASIMDFIEH---HHNRELETVpk---lVALISAVNngfdgidsgvDKGKVES-----KQSKEHTFI 128  Thermotogales...
YP_001276916   67 DVLEKLVPNLCVSGNNIKEIAELg--RQPSQARSSsn--hlIRVLGQSHdvs-----hvEKELGDHe----SKDQATDWI 133  Roseiflexus s...
YP_002728838   55 NSKIDIRLEVNSKSFELWDNFLKd-wRGWRKKNDLdf---lLQILYGISesln---sgiDKGSPKEdv--kVKPEEKRWL 125  Sulfurihydrog...

AAB84832      118 SSPFGYPkekih--lnclqKEFDDLQTILVRLFKYYISGvvnl----slfRRMLMKEAQVFFSHGLGETRIPSNDVTLWD 191  Methanothermo...
YP_002465098  119 SSPFGLEs-----------AIPNNLTAQMWALPWASLANysq------teRQNLLSALDKLFTQVGADTRRPINEVDLWS 181  Chloroflexus ...
NP_635380     142 SNPFGFE------------KGMEGLSSKLITIPYNKIND-----------RSFFVKSVVESFNYALGDTRRPTNEVTLTD 198  Methanosarcin...
YP_001738355  149 STAFGYEkeiellkdrglkKQFFEELSQILNNIFTELETkeqi---syesYQRFLSIITKYYSKTIGETRRSINEISLYD 225  Thermotoga sp...
YP_304896     140 SNPFGFE------------KGIEELTPKLTSIPYDKIND-----------RSFFVKSLVESFDYALGETRRPTNEVTLTD 196  Methanosarcin...
YP_002248916  149 TSAFGYGekiellennklkEEFFNALGEVLEKIKNGLPDisy------edYRNFISLIMNYYSKTIGETRRPINEISLFD 222  Thermodesulfo...
YP_001470831  381 SSPFGHPkekid--lnclqKIFDDLQDELIELFKNYRSLdak------hlRSNLINILKTPFSHALGETRIPANDVTLWD 452  Thermotoga le...
YP_002940969  129 SSAFGFEnyk------ieiDEIDRIKEEMYRKIEEHLTRfqkss-ndietLYKVIFCTKKYYLLFLGETRRPANDVTLWD 201  Thermotogales...
YP_001276916  134 ASPFGWEp-----------IQPDNLLKRLLGEPKTLLKNfsa------iaRKKILVSLQSVFAEAWGDTRRPINEVTLWD 196  Roseiflexus s...
YP_002728838  126 ANAFGSYkedi-----iylRESENIINGRIQNINNKVQSllgnshiffenLEELRKELKELLSGLLSDDRFPINDVSLWD 200  Sulfurihydrog...

AAB84832      192 HSYSTASRFKSILVANLCG-------ADIKDPELRIFGIFWNGIEFINKGRKIAEIKARKEIIERIKEKLKGKFEDEIPV 264  Methanothermo...
YP_002465098  182 WGLLVGALYKAALAGALLTgs----iPACNDLRWRLLSVRVNGFDYLLNVDRIPDLLAKQELLTDCLNRVRDVLEVTYPV 257  Chloroflexus ...
NP_635380     199 WSGIVAALYKSALASALLLki----kTDPTELKWRFLSIRFNSEQIWGNAQNIPILATRKKMLTEGLDRVKLLLEETYPL 274  Methanosarcin...
YP_001738355  226 YAYSIASLVKSNLAKMLVDgw----yEPRSKSKWTILSVNLDIPRLLSKGLKIGDILGYREETEQLFNEIKKFVEYDYPF 301  Thermotoga sp...
YP_304896     197 WSGIVAALYKSALAGSLLLge----kTDPLNLKWQFLVIKFNSEQIWGNAQNIPILATRKEMLTKGLDRVKVLLEEKYPL 272  Methanosarcin...
YP_002248916  223 YAHMIASLLKSNLVKIIGCgw----yEPRGNSKWRVMRINIDVIGLISKGLKIGDISGYKNELDSVYDKLKKIIEYIYPL 298  Thermodesulfo...
YP_001470831  453 HSYSTASLFKSVLAAITCGt-----nPNPQDLKWRIFAICWNGMEFINKGKKVAEIQSRNDVIENLKKKLTGIFEEEIPV 527  Thermotoga le...
YP_002940969  202 HSYSVATMMKCAVAQEFLKpe---ntFDPLHFDWKVFAVNFDVLGLLTKGIKIGDIKGYWKSVEKIFEEVKKMIEVTYPI 278  Thermotogales...
YP_001276916  197 WSSIVAALYKAELARCVLTtq----qRSPSDVAWRLLSIRVDGLQYLLSVSRIPDLLARRELLSDAWNRVQTLIEETYPL 272  Roseiflexus s...
YP_002728838  201 QAYMTTSMFKALLSDYILInqdftniPDRQEVRWRILGIQYNKLGLAEKGFKLASIEWYRQQTKEIDDSIKKLLEVEYPI 280  Sulfurihydrog...

AAB84832      265 GNSIYEDINGICFTFPE--FDRAEELAnqca------------kealKIFLEESENELWPFFTLSKPSKTLTVLASELKF 330  Methanothermo...
YP_002465098  258 GSEVYRDENGSVFVVPD--VSDLLAITdssgqslrki-ieqafaqgtVKSNSRLQLGGELTPHLELEQRPWWGQDPNWPR 334  Chloroflexus ...
NP_635380     275 GNEIYRDEDNSIFVVPD--ISYLLDKTsekn------------eplkQLIANEFGFEGEVVITPEIGNEWWAQKPDRENE 340  Methanosarcin...
YP_001738355  302 GNEIYRDETGIYFSSPS--FEEIKKFLee----------------ieKTFFNHLSFDVSLHIDTSRESRSMTVIASERMN 363  Thermotoga sp...
YP_304896     273 GNEVYRDQNNSLYVVPS--IPNLLEYTiseesktql--kqlianefaVDEEHNFGFKGEVILTTDIDNQAWCGQEPNNED 348  Methanosarcin...
YP_002248916  299 GNEIYRDSTGIYFSSPD--MDISEVIS--------------------KLREDLTCVDFELQISQSHSSRSLVSLASEREK 356  Thermodesulfo...
YP_001470831  528 GNVVFEDMNGIYFTFPD--LNRACDLAeeca------------kialETIQKETQNELWPFFILSEATRTLTIIANVQRS 593  Thermotoga le...
YP_002940969  279 GNEIFRDTKGIYFLTAAveLHELKEEIlkkirgiepeimaciteiplETKIPPEEQGDRKTIEAKKKELLLKSIPEARKK 358  Thermotogales...
YP_001276916  273 GLEVYRDENGPVFVVPD--IENLLDESqvaqdgger--ktlrdlirdAFAAGTVKNDSSLAIRHERVPELYLDDKPWKGQ 348  Roseiflexus s...
YP_002728838  281 GNEVYRDDTGIYFIVGEn-LGKNKDNNlavlvddl----kpleeeiiNIFNEKLEGEVCPVIILTKASRGLMNLGDLLEK 355  Sulfurihydrog...

AAB84832      331 ASSRRVYPKITpalfidkkqkkiiADNPEMPIPQEGEDICPLCRLRA-------KPIEKERCEICSERIRG-RLANWSNK 402  Methanothermo...
YP_002465098  335 SSNDELPDISSllnqmi-vspanaADIGQYWDNKEATDICTVCGLRPqgp--sgKATERNVCDICEARRAD-RSKQWATS 410  Chloroflexus ...
NP_635380     341 MQNDEIPPIAKilsnqrlyspadpKDVAKFWEGTSNRGICTISWLRPqgp--tsKGFNRKASDCWVERVTW-RANEWYHS 417  Methanosarcin...
YP_001738355  364 ALKKISFPHISgmmk-----hqrnAAINNNQENKFSFEKCPVCGVRM-------KSEKNDRCEVCDKRYKK-RAESWNKD 430  Thermotoga sp...
YP_304896     349 KEKNEIPPIARilsndelcspadvNAVENFWKDVSDCGICTISWLRPqgp--tsKGFNRKASDCWVKRVTW-RASEWYHS 425  Methanosarcin...
YP_002248916  357 SLSEIVFPHIS-------------KTKVSASMDHEGKDICPVCRIRL-------KEESKDRCIRCQERYEK-RARSWLDK 415  Thermodesulfo...
YP_001470831  594 AFEKKKVPKMTpvlfve--dkeryLENPDLPSFTVRQSICPVCGIRP-------RDEGKERCKICYKRRQG-RLSKWLSN 663  Thermotoga le...
YP_002940969  359 ALERVSFPAYSe------------GFPCNEFGPENNKEVCPICRLRT-------VERGKEICNHCLNRRTN-RSQEWQMD 418  Thermotogales...
YP_001276916  349 PAPQELPPIVNhlkrdi--rettdPQWLETLWRGQNAEVCTVCGLRPqgp--dpKAQERKVCDTCEQRRTD-RAQQWVGT 423  Roseiflexus s...
YP_002728838  356 AKENFLYVKTDnki--------tqTLMQNVNNTSTAIGICPLCKVRLiyeydkqKNNSPTICKTCDERIHHyQVKKWLEE 427  Sulfurihydrog...

AAB84832      403 KE----NTIWIDEVADKNNRIALIALNFDLDKWFDgtmvgtiysqtykdwkhskkwekknvkknansvlngpieaikdhv 478  Methanothermo...
YP_002465098  411 ETd---RTIWIDEVADTNGRFALIVGQFDLTHWLD--------------------------------------------- 442  Chloroflexus ...
NP_635380     418 LD----STIWIDEVADSNDRICLLTGRFDLLEWLK--------------------------------------------- 448  Methanosarcin...
YP_001738355  431 PK----KTVWLDEVSDKNGCVAMIVGKFNLNKWLSgelldtlisttfeewksengniqlcsk------------------ 488  Thermotoga sp...
YP_304896     426 LD----NTIWIDEVADSNGRICLLTGRLDLLEWLK--------------------------------------------- 456  Methanosarcin...
YP_002248916  416 NErs-kETIWIDEVADHNDRVALIFGQFDLRKWLSgeyldtfisqtfeswrnennsicsk-------------------- 474  Thermodesulfo...
YP_001470831  664 RE----ETIWIDEVADKNNKIALISLNFYLDKWLDgtmvgtiysqtfedwlnskkakkffenkqniqklr---------- 729  Thermotoga le...
YP_002940969  419 PK----SSIWIDEISDHNDRVALVVGMFKIDEWLN--------------------------------------------- 449  Thermotogales...
YP_001276916  424 LRcgdhPTIWIDDLTDIHGRYALIVGAFDLSGWLA--------------------------------------------- 458  Roseiflexus s...
YP_002728838  428 ISk---ETIWTSEIKDKNDRIALISLRLELKDWLNgnmlnsllgnmglgdftvekgkiiklilkgivdte---------- 494  Sulfurihydrog...

AAB84832      479 ykilnyilenedsneekaaklldtffeeeiglrnkkdlkkefkNHLQNIRENIGADLNKEnla----------------- 541  Methanothermo...
YP_002465098  443 -------------------------------------------GSLLQSLLLIAPHDPQNtnn----------------- 462  Chloroflexus ...
NP_635380     449 -------------------------------------------PDGYISTIKIRSEPNGK-------------------- 465  Methanosarcin...
YP_001738355  489 -----------------lgihkiedlerkfqdmfknskldqtgKELCESLVGIKIDDFSKlwnslaerdatg-------- 543  Thermotoga sp...
YP_304896     457 -------------------------------------------PDGYISTIKVGSDANGK-------------------- 473  Methanosarcin...
YP_002248916  475 ------------------lsinkiedlekqfesmffktindnqKELCKSFIGIKPENFTKnfwepiaerdatgqamnltn 536  Thermodesulfo...
YP_001470831  730 ---------nkgvniekknnmnlskellktitdedikedagfkSNLINTFFEDISSSQDHssdgnyverfvnnlkerlkp 800  Thermotoga le...
YP_002940969  450 -------------------------------------------GSFIQTLTFNEPSTENA-------------------- 466  Thermotogales...
YP_001276916  459 -------------------------------------------GDLVRTLVVRQPDNKNRtt------------------ 477  Roseiflexus s...
YP_002728838  495 --------iqeiinkiekeiciekfknlytvislkdsngnficRENLNTLQNEIRNTSNRaeygalisvvgfir---dri 563  Sulfurihydrog...

AAB84832      542 ---------tyLFTQNPSPARLYRIWKETEEFFD-----LLINKITD---IYAYRWKRIGFSIDTHELKGRLKEEYKni- 603  Methanothermo...
YP_002465098  463 ---------kpVTSKTPSFSRLRRIWETTRAFWHevqdaTLQALSDDrrrLKMYLDQQPNLGPFHVYDLVVGPTDLSvv- 532  Chloroflexus ...
NP_635380     466 -----------VITKTPSFARMNRIWRTTKKFWEd----VENELGVK---IGQIDNRLKIIGKFQPENNSSLKMGHSyk- 526  Methanosarcin...
YP_001738355  544 yalnlvneeekARHLIKLLFRKHPSFARLRRIWSt----TKEFIDQTi--LETIINSFIPSNPRTKRIQLVISPNPS--- 614  Thermotoga sp...
YP_304896     474 -----------VIPKTPSFARMHRIWRTTKKFWEd----AKEDLAKK---IGRVDNRLKIFGNFQSENNNSLKRDHSyk- 534  Methanosarcin...
YP_002248916  537 npdkakyliklLFRKHPSPARIRRIWNTTEDFIKn----TLINNILS---KHSYGEASSHVNLRNKRIQLIISPSPN--- 606  Thermodesulfo...
YP_001470831  801 epfnpsnlqklLFTQNPSPARLYRIWQETTEFFDl----VVSEVKNK---IYSNKWKRIKFFVNYTDLKSKLKQGMG--- 870  Thermotoga le...
YP_002940969  467 -----------SNPRNNDVRKHPSPARIRRVWET-----TEEFIRETv--FKGILNNYEYPALRKQRIELEINPNPK--- 525  Thermotogales...
YP_001276916  478 ----------dKVSKNPSFARLRRIWETTYAFWQq----VGSTEPGMl--SDAVIGRVVGRAEPRLEIKCSLNVQTL--- 538  Roseiflexus s...
YP_002728838  564 ygnqssnqdgyILKILENLDEFLKKLKISQDLFQf----VKQLQDSGf--YSLYKTIVEKLNELKAKLDSKYNSTNSsnf 637  Sulfurihydrog...

AAB84832      604 -kELEKGSLIIKISGLDPETLLVFHDRn-GEFYTIESLGKFKFKnkVGEEAVKEALKQGIKHLAPEDEPEKNLIEVGKTI 681  Methanothermo...
YP_002465098  533 wvPPQNGEKGYLLTADNLCYIARQLGAesGIYTSPAAAAIFVEEy-LCEQFVKHARQPILRNPDASPSQGRANLVSGIKI 611  Chloroflexus ...
NP_635380     527 -aMLDRIGFSIFYGKEDEFLVIENHKEl-ANKFGFDSEKYVDKN--PTRQLKEYLSTKKVKIYDSEGKNRSNPIGTLEIL 602  Methanosarcin...
YP_001738355  615 --IPKNATCDIIVGGVRFSPVCIDNTK--GIFISTTNLEILSKFg-RTVEEIAEALSGQNIKLKTEEEKNWKDYMIIEAK 689  Thermotoga sp...
YP_304896     535 -aMLDRIGFSIFCGRNNEFLIIENLTEl-ANKFDFDSGKSTDKS--PTEYLKKYLSNKKVKIYDSEGKKRLNPIGCLKIL 610  Methanosarcin...
YP_002248916  607 --IPIGSTIDIDIDGVRLSPVCVDKSK--GIFITTTNLQILSIKg-KTPEEISLWMKEKPIKVKKEGDVQWVGGYRITNV 681  Thermodesulfo...
YP_001470831  871 --IEEKTPYLVQIDDLKPQKLLVFHDEn-GEFYTIESLGKFKFNnnIGEEAVKEALKQEFKHLAPEDDPDENLLNKSVKP 947  Thermotoga le...
YP_002940969  526 --VPEGSTCDISISGVRFSPVCVDSVR--GLFVTTINLEILSKFg-KTVKEIAEALSGQNIKLKTEPEKSWRDFRIAKAK 600  Thermotogales...
YP_001276916  539 --VPYHTYELVLPEGIRLSVLWDGNGF--VTCDNLTYLNGLMRS--GKIQDILKQGKTFLIEASDDTGKRRQLGNITLSQ 612  Roseiflexus s...
YP_002728838  638 dkLIQYLRTEKSSSSLTEKEIKEFKQEieNILTQCKPIQNFDIDtlIKNSLYPFSINEELLNFYSKYNSVKEYFNEIFFG 717  Sulfurihydrog...

AAB84832      682 KTEDnlYFEKYYPLIEINR-------SPLSLRFIVPALDSVKIIEMIAELYNKRFEKVLGKLPLNLKLLVAKRKFPLYIL 754  Methanothermo...
YP_002465098  612 NQIDy-QQNAYATAIPILA-------EPRSFLMLVPADKSLEVLKQIKAKYECEMGKVRDRLPLHLGCVFAARRTPIRAV 683  Chloroflexus ...
NP_635380     603 EMKE--EDTPYVPLIPILT-------EPSIFMAIIPAEKALDVSRLIKIKYETEMGKVRNRLPLSLGMVFAKSHTPLAAL 673  Methanosarcin...
YP_001738355  690 PADD--EFQDYIPYIEIYD-------FPDQFMILVPAYEALDIAEKILMEYEKQFSKVRDRLPFHLGVIAFHRRTPLYIV 760  Thermotoga sp...
YP_304896     611 KIDE--ENTSYVPVIPILA-------EPSIFMTIIPADKALEASILIKTKYEEEMGKVRNRLPLSLGMVFAKSHTPLAAL 681  Methanosarcin...
YP_002248916  682 IPPNe-AFQDYYPYIPIYN-------YPDQFMLLIPAYDALNIAQKIFEQYEVQFSKVMDRLPFHLGIIAFHRRTPLYIA 753  Thermodesulfo...
YP_001470831  948 DENNi-KIEEYYPLIEINK-------SPFSLRLIVPAQDSMKIIALVTDLYNEMFKRVIGKLSLNIKLLVTKRKFPLYLF 1019 Thermotoga le...
YP_002940969  601 PADD--KYQDYLPYIKIYD-------FPDQFMILVPAYETLDIAEKIVEEYERQFSKVRDRLPLHLGVIAFHRRTPLYVV 671  Thermotogales...
YP_001276916  613 DAVPi-ANGSFVPALPLLA-------EPRVFMALVPADRALEVIRQIKTKYEREMGKVRNRLPLHLGVVFAPRPTPLRAV 684  Roseiflexus s...
YP_002728838  718 SIIGt-QWENWIKQTPLNAkinwqdeKIEWDKFTDENDPALDILSTLLLQFLLRKNPSPARLRRIWETTQNFFEEIKREI 796  Sulfurihydrog...

AAB84832      755 LEAEKRMLKDEEFKKQTPMDPWWSVERLDEHYN----------------------------------------------- 787  Methanothermo...
YP_002465098  684 LEAGRAMLDREPLLQQWQIKWVDRQPSHVVLQLersgysvqwqiplkmgdgttddlwypyffletngddskadasnrrav 763  Chloroflexus ...
NP_635380     674 MDAGRKMLRKSNKEKSAKEDKWILEENPIKNYNsftlkfnngikwkipsimgdek-----tldiwypyfyvdgelrnrsd 748  Methanosarcin...
YP_001738355  761 MDAARRLLKRFEMSKTIEADVIKVEDIAGDSELgkckklvlq--------------------------------vdrrei 808  Thermotoga sp...
YP_304896     682 MDAGRRMLRKSNKDRSVNEDKWILEEDPIENDNkftlkfnngtkweisskmgdei-----ttdywypyfyaqgnfqersn 756  Methanosarcin...
YP_002248916  754 MDAAKRLIKAFNTKTKTIKAKVESIEDTPENKHrkltitpd---------------------------------qdfssv 800  Thermodesulfo...
YP_001470831 1020 LDAENRMLEDEEFKKQVAMDPWWNIQRHDEFYGf---------------------------------------------- 1053 Thermotoga le...
YP_002940969  672 MDAAKRLLKKFESSKTIVVDVERVEDMKDPISGmskklllr---------------------------------vnkrri 718  Thermotogales...
YP_001276916  685 LDAGRAMLERQTVASVWEVLCCAQKMVSKGDSLparfqpdqagqfaewyevtlqkddqrltwhipalmgdsqtedlwypy 764  Roseiflexus s...
YP_002728838  797 LDENLLGIPNWRRKRIVFELPYIQGIKDTGEELegd-------------------------------------------g 833  Sulfurihydrog...

AAB84832      788 --FYPIKPANGEKYTLDDLSRLSRGKIFYLYPG------------------YFDFELLSATTDRYNICYegk-krGHEDH 846  Methanothermo...
YP_002465098  764 kvLMPQSNGKKVDEWIVHAGDLRIGETIYRWSS------------------TFDFEFLDTTARRFEIYY------DEHGR 819  Chloroflexus ...
NP_635380     749 sfIHSFKNPENSDRWLVHVSELKEGDIVGILPS------------------KFDFEFLDSASRRFEICY------DEKGN 804  Methanosarcin...
YP_001738355  809 plNWVVSYSTKDPEVEDLWYPYLRICSAEKPDRtlcfdytgsgdyvvhikeIKEKDRIKIEPSYFKLCYi----eESSDR 884  Thermotoga sp...
YP_304896     757 sfMHSFRNYENFNRWLIHVSELKKGDTVSILPS------------------KFDFEFLDSASRRFEICY------DEKGY 812  Methanosarcin...
YP_002248916  801 plEWQISYSTGDPNQEDEWHPYIRIENKPSHTGgyffdydgmgnyvvhvkgLKSNDCIKIETSYFKLVFl----eSASDR 876  Thermodesulfo...
YP_001470831 1054 --YPAKPVEHENKYTLDDLNPISKGKIFYLYPG------------------YFDFDLLSENTDRYNIAYskgekiKRADE 1113 Thermotoga le...
YP_002940969  719 plKWVVSYSTKDPDVEDLWYPYLRLCNKGKPNRklcldytgngnyvvhikeIKEGDELEIEPSYFKLCYi----eEASDR 794  Thermotogales...
YP_001276916  765 vfLDDQVEPTTRKRYFKSRNPWKGCDGWLVHAAelqvgdq-----vwfapaTFDFEFLDTTTRRFEIHY------DTNGR 833  Roseiflexus s...
YP_002728838  834 llFWALPSENKDKTYIYLISSIEDFIRKYANKDtlkrlne----nnledidENNFEDFKIELKKYSEKEn----rETGSN 905  Sulfurihydrog...

AAB84832      847 RLFSG----RPLYFHQIPQ-ILELWDLLSSNLSNSQINf--IEKALTSKLREWKNVKDAnk---eNTFRIFAETTLKDAF 916  Methanothermo...
YP_002465098  820 RPRRT----RPFYLEDLDR-LEELWCYMMRLTKTQRHQ---VIRTIEATREAWYGPDDNgqpttdQVFKQFVADTLAGAA 891  Chloroflexus ...
NP_635380     805 RRGSLka-lRPYLLEELDN-FTDLWNICSKNLSNTQIRn--IITLIEKKREEWDIGEDT------IVFENFVHDVLYNAN 874  Methanosarcin...
YP_001738355  885 FNVDE----NLKFIDDIHH-IKNLWEMVKRNLLSKKWT---LSQLYSFWKELERIKEYDe-----ETFEYFLESNLINIL 951  Thermotoga sp...
YP_304896     813 RRDSLka-lRPYLLEELDN-FTYLWDLCSKNLSNTQIKn--VITLVEKKREEWAVGEDT------TVFETFVHDVLYNAN 882  Methanosarcin...
YP_002248916  877 FRIDD----NLRALDDIKR-IDDLWNDIQNLVRNRNIG---LAQVYAFWQETKKRYEDYng---dSIWKKFVSSSLINIF 945  Thermodesulfo...
YP_001470831 1114 IYRLLt--eRPYYFYEISE-ILELWDVLTNLTSSQIHF---VEEALTLKIREWREVKDRe-----NVFMNFAEATLKDAF 1182 Thermotoga le...
YP_002940969  795 FYVDE----NLKFLDDIHE-IQNLWKIVERKLRSKKWT---ISQLYAFLEELEKIKEYNg-----ETFEQFLRSSLINIL 861  Thermotogales...
YP_001276916  834 RANRHt---RPFYLDDLER-FDRLWEVFLRLSTTQRHQ---VVRMIEATREEWFGQDHGgtsvtdQVFRQFVHDTLAGAE 906  Roseiflexus s...
YP_002728838  906 LCSLQksniKNFVLYNSYAsITDPTPVGWQVIIPTEYVpkfIDLIMEKYNKEFKYVYGKlpihigIIIQDYKKPLYIGLN 985  Sulfurihydrog...

AAB84832      917 Gh---KWDGLREENRFFLISSSINMLLLDTINLFTHVTG 952  Methanothermobacter thermautotrophicus str. Delta H
YP_002465098  892 WpkgqDWNTIPAEWRDKLIQAGVRGELADLAELHMEILK 930  Chloroflexus aggregans DSM 9485
NP_635380     875 Wn---NGKRPDDAKMTELEDAAKSGKLRDILELNLNILK 910  Methanosarcina mazei Go1
YP_001738355  952 Gl--nPSSDEFEFLKKAIEDGLFELCLHWNLQVRKEKAE 988  Thermotoga sp. RQ2
YP_304896     883 Wn---NGRRPDDAKMSELEDAAKSGKLRDILELYMNILK 918  Methanosarcina barkeri str. Fusaro
YP_002248916  946 K----LSPTRDRDLFKKFFQATKDGLLDICIHWNLKVRK 980  Thermodesulfovibrio yellowstonii DSM 11347
YP_001470831 1183 Nn---KWDKLRDETKWFLLKSACNGLLLDTINLFKRTLA 1218 Thermotoga lettingae TMO
YP_002940969  862 Dl--dDSSNEYNLLKTSVEDSLFELCLYWNLQVRKEKIG 898  Thermotogales bacterium TBF 19.5.1
YP_001276916  907 W----DWKALSQNIRAQLVAAGTKGELADLLELRMEILK 941  Roseiflexus sp. RS-1
YP_002728838  986 Al---RKIRRDVKNIDKLYQNGTKFCMKYHQKILNYAKP 1021 Sulfurihydrogenibium azorense Az-Fu1
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