Conserved Protein Domain Family
Cas8a1_I-A
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cd09697: Cas8a1_I-A 
CRISPR/Cas system-associated protein Cas8a1
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as Csx8 family
Links
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Statistics
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PSSM-Id: 187828
Aligned: 3 rows
Threshold Bit Score: 540.644
Created: 6-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAL95378   12 FDTAISASDWKYSAAITGLIYYFKELEKKyeikkitiDEITDSYLLYNKEDINEENYLDFIEKFYSkyseDTLAHKKLEN 91  Fusobacterium nucl...
AAO35717   10 YDTMLEPSDWRFSATIVGLLQYLNYHDLD--------YKLEEDYILYNSSGINEERYLDFVEYKYG----EELHHRLVEN 77  Clostridium tetani...
YP_698243   6 FDCTLESGDWRESATIVGLIKYFDFLYQNgvadkselYEFEDDYLRYNSNYISEENYLLFVEKYFK----DAMHHKVVEN 81  Clostridium perfri...

AAL95378   92 QLKHtKEFTSEIIKSIKENMSANTVLKKVFSKTKFDGTNKDEVLKLLDENRHSIIKETFRNKKDLYDNYCQTSRLLEKgD 171 Fusobacterium nucl...
AAO35717   78 ILSN-EEITEEQLKLINEKLVANTIMKKTFGKIKFDNTNKKEILDIINKNRYELIRETFRRKSNMYANYGNTNQLFND-S 155 Clostridium tetani...
YP_698243  82 ILLK-DELSEDEISIINDKLKANQAMKSIFGKIKYTGENKEEILDLIEKNRLKLIKETYRRGKSLYSNFANENLLFSD-N 159 Clostridium perfri...

AAL95378  172 NSPCRLKGYYFDPNRKSKATGYNFVSSSVDYFDDEIFDFIPFAFTGSsFETIFLNDNLDLEILEnmnyklreyfseeken 251 Fusobacterium nucl...
AAO35717  156 QDHCRLLGYCIDTGKKGKSTGFNFMMSTFVGSDIKEFDFIPFAFEGS-REAFFINDNYTIQRLK---------------- 218 Clostridium tetani...
YP_698243 160 NKVCRLVNYCADMGKKGKSLGYYWDNNTFEFKDEKIFDFIPFAFSKS-YDAFFINNNVSIKELK---------------- 222 Clostridium perfri...

AAL95378  252 eterlkslKQEKAIKEkkneeteGNQnsvpLKKLFLNILQKKVDYIKYGMEIIYKNRDKEYFETWYLRNESIKVLKE--- 328 Fusobacterium nucl...
AAO35717  219 --------ISNEILSKkieddleGENkrkdARQTLFKAIMETSDFIKRDVEVILKDISKEYFETLYIRKESIDIFKEfin 290 Clostridium tetani...
YP_698243 223 --------KSNSFIEN-------SEN----TRTTLFGNMKESAEYIGFDVEVILKSRDKNYYETVYVREKAINIFKQs-- 281 Clostridium perfri...

AAL95378  329 -IEDFSKLDIRIKITDKYYFNLLDEVFSAVLNLSLLTNSILYLLKDREsfikidttrenlsklfkYNYAINELIKVNQII 407 Fusobacterium nucl...
AAO35717  291 eKIEYKSFCFSHKVTDKYYINIQKKVTESILNNVLLDELIEIFLKEKN-----------------RSYLVLQLIKINVLI 353 Clostridium tetani...
YP_698243 282 dDFDYKGIKFWYRDDEKNSKYMEPEVVNRILNGIRMDSIIELLFKSKNn----------------HSYNIKTLIAINNLI 345 Clostridium perfri...

AAL95378  408 RNGgKEMDENLKKsIKACSIAVVKKFIKenslNKLASYRQKLLSSVVAKNHKRILDVLTQLSVYSGVYFSFAFDYIENQT 487 Fusobacterium nucl...
AAO35717  354 RRD-KTMKDRLKG-AFACAKQVSKAIES----NKLDSYKQKLTSSIIFKDYDRVCQILLQLSNYSGIEFGFVYDLYDDFE 427 Clostridium tetani...
YP_698243 346 YEGgSEMTEKMKS-AYASAKEVRDKLKNq--eNKINSYKQKLISAVTFKDKDRFCEILLQLSSFSGVVFDFAYDLFEDFE 422 Clostridium perfri...

AAL95378  488 QNEDIIHYFILEL 500 Fusobacterium nucleatum subsp. nucleatum ATCC 25586
AAO35717  428 ENKDLAYTFINAL 440 Clostridium tetani E88
YP_698243 423 NNKNLAYTFINAL 435 Clostridium perfringens SM101
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