Conserved Protein Domain Family
Cas7_I-C
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cd09687: Cas7_I-C 
CRISPR/Cas system-associated RAMP superfamily protein Cas7
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family
Links
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Statistics
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PSSM-Id: 187818
Aligned: 11 rows
Threshold Bit Score: 234.645
Created: 5-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAB85577       9 MDLVFYGNSLNYDQGSGNYQELKKItk-wDGRQYTLVSRYALRYSMLDTADKfglfelaeadnlvksgkgdstviqpate 87  Methanothermoba...
AAM25781      13 YLIKVSTGNINASHTEGNVVIAKKVtl-pDGSSVPYFSGQAKRRMLRDRLEDlgfalsevaak------------vsgqe 79  Thermoanaerobac...
AAL81246      13 PHSALNMLGIDENLPDRNVTRVKTLr--rGGNRYVYVSPQAWRYWWRTTLKEyfkwelsplf-------------reekq 77  Pyrococcus furi...
AAN50390       9 ILTPHGVAANNRGENEGNLSTLQKLl--wNGEVHSTVSGEAIRYALRETWMEdhenllnrkiks----------egydwq 76  Leptospira inte...
AAR38874       8 SILARVYGNVNADETIGNRVTIKKFys-sEGEVLPFVSARAIKYSIRQALKErgfeidpfva--------------ekke 72  Nanoarchaeum eq...
YP_001038696  12 LTKASYSSLNGADKEADNIVSIKKIqm-nDGKEYPYCSSQAVRRALREQLASmgwelsettva-----------kqkkga 79  Clostridium the...
ZP_05005941    8 MLVSVEAGAPNNGRSADTTARVKYAt--vRGRRHPYVSAQAVRRWIRDGMVRqgvpaspvtrvgk--------aqqraqk 77  Streptomyces cl...
YP_002731104  11 ISIIFDAMSLNYGEGVGNISELKKLs--rSGELYSYESRQAIRFDTYRLLKEifgidsdkeeplt--------gdndvvq 80  Persephonella m...
NP_142171     13 TLTKVEGANLNSNGTEGVISVLKKVrdpvDGREYVRVSGQSVKYHLRQILKElgwelsqiyprs----------eggqkv 82  Pyrococcus hori...
YP_002534251  10 TIVFESSAVNRDENIANNIQSLKKLr--rEDGVYTFFSRASMRHHVFNALVRkhgwkparvak------------dgdvi 75  Thermotoga neap...
AAO35718      11 TLTVVANMTSNYSEGLGNIASVQKVf--kNRKVYTIRSRESLKNAIMVQSGMyddlqtevdg--------------atqk 74  Clostridium tet...

AAB85577      88 flltgDILEYPEFDL--FGYLITet------kpQNFRTAPVKVGHAVSMTPFMYDAHFNANiglanrm-----------r 148 Methanothermoba...
AAM25781      80 vtppvQPWRYIDEDL--FGYMDPs--------gSRRRTSPVRVSAGIGMFPFQGDRDLGTRsferfg------------- 136 Thermoanaerobac...
AAL81246      78 vftaaNPIKYPDDDV--FGYMRAykkn--nvnvTVTRVSPLKNTPLISVLPDRSSLTIDEGyasr--------------- 138 Pyrococcus furi...
AAN50390      77 detfkKPDRYLDDTI--LGFMDPkk-------eTNKRRASLEITRAVSTRPWIGDVSFNVAsvgaq-------------- 133 Leptospira inte...
AAR38874      73 mrdsgNPIKYVDNDL--FGFMAPykgkkkgeggSVNRQAPIAISYFKALKNTPINVEFGARfprentikidkekteesnq 150 Nanoarchaeum eq...
YP_001038696  80 astlcEPSKYIDDDL--FGFMNAds------skTVKRTSPVRVSPLVALEPYGGGMDFGTNymsv--------------- 136 Clostridium the...
ZP_05005941   78 antdaDPITYPDDDL--FGYMRAgakk--dddaTTLRDSPFMLGTLLSVTPAHPTEDFGVMarg---------------- 137 Streptomyces cl...
YP_002731104  81 fkpeaNVKDYIEADL--FGYMKTekd-----kgALTRPAVVRINPAISLEPMNLDVEFGTNlnfaq-------------- 139 Persephonella m...
NP_142171     83 ivsagEPYKYIDDDL--FGYMIAkkie--gknaTLRRTSVVRTNGMISIFPYQEDRDFGVRydp---------------- 142 Pyrococcus hori...
YP_002534251  76 qfdvlEESILTSEELdfFGYMRTfe------saSLSRKAPVGMTKAVSLEKWEGDMAFYANhdlvqra-----------r 138 Thermotoga neap...
AAO35718      75 lankeLNASNCRALE--GGYMSTkg-------tTNIRKSSFYLTDAISCESFVNETRFHNNlylannaaqak---ninlq 142 Clostridium tet...

AAB85577     149 krhgemKPNPFTAEEHQTFYQYSIVVDVDSIGeievyiseksdvtladgkyklesiekvsslkgdglliklkkgknkkei 228 Methanothermoba...
AAM25781     137 -qavsaGGNMFETELYANLFKGNMLVELDRVGvfsdlelgdkpkdipahl------------------------------ 185 Thermoanaerobac...
AAL81246     139 ---hegDPVPYSQEFYSTVLKGAFSLDLDLVGrfttknkagyknlltrsdipkkgkageiv------------------- 196 Pyrococcus furi...
AAN50390     134 --rtnkNPIPYATEIHATRYQYSFALSGDDVKs----------------------------------------------- 164 Leptospira inte...
AAR38874     151 esdqtlNPIPFEVEVADFIGRLNVLIYENVGKfteee------------------------------------------- 187 Nanoarchaeum eq...
YP_001038696 137 --kaggTPNIFETEIHSGYYVGTVLIELDRVGekspgdey---------------------------------------- 174 Clostridium the...
ZP_05005941  138 ----vsEPVLHGHEFYSADLAAPFLLDLPRIGtftlpnahgvgrpnylsqeaalqva----------------------- 190 Streptomyces cl...
YP_002731104 140 --ragtNPNPFQFEHHSSLYSYTITIELDKVGkdende------------------------------------------ 175 Persephonella m...
NP_142171    143 ---tgdQHNIYETEITTNVMRGNYFIELDRLGvfveglevpklnpgeyslev---------------------------- 191 Pyrococcus hori...
YP_002534251 139 eigesaDPNPFSKEEHLSLYKYSVVVDLENIGkekviinekqcek----------------------------------- 183 Thermotoga neap...
AAO35718     143 eksseaGLMPYQYEYDKSLKIYSITIDLEMIGkdenfqqe---------------------------------------- 182 Clostridium tet...

AAB85577     229 lqsenvelcdfekidkvyriryrlkddeKIKKr-IMNLIKTVMNLKRSIK-----ARDEDLSPKIMVMGLYRdSPYMTFK 302 Methanothermoba...
AAM25781     186 -----------ekiekngrvfyvlpleeRKKR--LKALLEALGLLWGGGRt---aRMLSDLSPRFVAYSRLT-IKHPVFL 248 Thermoanaerobac...
AAL81246     197 keieeleklareigveikeeewimpkevRKKR--AVETIKALRYLTGGAKq---tQYHTDVTPKFFLGIIVNgGINPFIS 271 Pyrococcus furi...
AAN50390     165 ----------------------------EWKGl-ALDGLASLRRVAGNHS-----RFLYDFSPESIVLRVTH-DPAPRIL 209 Leptospira inte...
AAR38874     188 ------------------------ltnvQDKNi-LQNILQKEGKLYVLPEe----ERKKRLKAFLEILLIPS-YVLPRRT 237 Nanoarchaeum eq...
YP_001038696 175 --------------------dlslsqdeKKKR--VNALVDAIQNLWTVGRq---sRFLSDVSPKFVAAAVLK-VKNPIFL 228 Clostridium the...
ZP_05005941  191 ----raaalgagaesfrgqdsvrlpvaeRRRR--AALLLESIAHLHGGAKq---aLHYGDRVPHVIVLVPFHgGVNPLTH 261 Streptomyces cl...
YP_002731104 176 -----------------------idiepEEKArrINMLLDVLKILNRNIK-----GRMESLNPLFAIGGVYN-VKNPFFL 226 Persephonella m...
NP_142171    192 --------isvkdvtgrevtlyvlpreeREKR--LKALLTAIMEYHGGAKl---sNFFTKVYPEVMMLVKLK-RKIPVVG 257 Pyrococcus hori...
YP_002534251 184 ----------------lnrlfgidlkelKEKEs-IANDKGTISLESVGEKsyrilVTLNDPEKQKRLKQFFDiIINGFEI 246 Thermotoga neap...
AAO35718     183 --------------------edykeadnKEKAdrVNSILNAIENLSLTVK-----GNLDNAEPVFVVGGLSN-RKTHYFE 236 Clostridium tet...

AAB85577     303 DRIVLldeyteeeydeieeqetdngrilKVRHVTSKQRKPVf-EVEGLEAEs-LDVDk-vEEFVEgifddg-elsrvAVF 378 Methanothermoba...
AAM25781     249 EALQVsysegry----------elilepLISALQKFSNYRQn-TLFGLEKGf-FSNE---EEIRQnlepygkvmdlyEAI 313 Thermoanaerobac...
AAL81246     272 GIVREekgeii------------ldaeaLATRLEDFSEIIDseLFLGYDKG--FVKEl-gLDIEAlksavsievmegKVG 336 Pyrococcus furi...
AAN50390     210 YCFREeg-------------------dtIDLKNLAKRVASGdvKAEELILGgeIASEqdaIELKTkgat-----vfpGIK 265 Leptospira inte...
AAR38874     238 NSLNIpeykvaliv------lnkegvlpIYQYLDYVKEGVVnlEKLKRLKE--IVEEa-gSEAYIidydgw-veeeiFPK 307 Nanoarchaeum eq...
YP_001038696 229 ECIKIgssgs-------------vdmslVKNTVDDFHKQIId-YAIGERKGf-FAQD---SETALpl---------gQCF 281 Clostridium the...
ZP_05005941  262 VITGDeeglr-------------irgdvLRGELEAWAGEWEapVRIGWRPG--FRDDl-rERFEKecaaei-adrtvVIG 324 Streptomyces cl...
YP_002731104 227 GRLKVsynkenrky------svktpiiaSILDISFNGEKVKdnTHIGIIEGy-WENE---SDIKEllpdnq-vhninDFF 295 Persephonella m...
NP_142171    258 DSLRVkegyidgk--------miidverIREAIETFSDNVEe-AYIGLFKSk-FANV---DELEGtfenl--ekvriVSM 322 Pyrococcus hori...
YP_002534251 247 HSSTEswcvspvf-------iviattrlPVTLFNPYIKLDDgkIDVDLVAK--IAEEn--TNVIDyriwgv-pfilkGEV 314 Thermotoga neap...
AAO35718     237 NVVKVee--------------------eKLIISEDLKDKIEkgYHVGLLEGktLQNE---KEIKEqlnp----isitKFF 289 Clostridium tet...

AAB85577     379 TDPSVELRK 387 Methanothermobacter thermautotrophicus str. Delta H
AAM25781     314 QEAQKDVES 322 Thermoanaerobacter tengcongensis MB4
AAL81246     337 EVIESFAEE 345 Pyrococcus furiosus DSM 3638
AAN50390     266 AAVEDAKKR 274 Leptospira interrogans serovar Lai str. 56601
AAR38874     308 ITVKQAVEK 316 Nanoarchaeum equitans Kin4-M
YP_001038696 282 EKIHSWVEE 290 Clostridium thermocellum ATCC 27405
ZP_05005941  325 HPRTILLEL 333 Streptomyces clavuligerus ATCC 27064
YP_002731104 296 EELKKKVND 304 Persephonella marina EX-H1
NP_142171    323 KELRKVIEE 331 Pyrococcus horikoshii OT3
YP_002534251 315 DKLCKGPKD 323 Thermotoga neapolitana DSM 4359
AAO35718     290 DMIRHEVNT 298 Clostridium tetani E88
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