Conserved Protein Domain Family
Cas7_I-A
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cd09685: Cas7_I-A 
CRISPR/Cas system-associated RAMP superfamily protein Cas7
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as DevR family
Links
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Statistics
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PSSM-Id: 187816
Aligned: 7 rows
Threshold Bit Score: 326.708
Created: 5-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
AAL80766    6 SGRIRLNAHSLNAQGGGGtNYIEITKTKVTVrtengwTVVEVPAITGNMLKHWHFVGFVDYFKTTpyGVNLTERALRYNG 85  Pyrococcus furiosu...
BAB64980   10 SARYLVNVEDLNNVESAG-NYVRHRRAPIIVkegntyTVTYVPAVSGEMIAHGYQMNLVEIAIER--NLPVEELAKQGIL 86  Sulfolobus tokodai...
AAL62629    7 TARVEVQVSALSGLGAIG-NYNQVATARILHn----gALYEVPVITGNALKHWHAVYAVEAYQALg-GNMLNELCKRGIG 80  Pyrobaculum aeroph...
NP_343397   5 SGRFLVNLESLNGVESIG-NLTKHRTAPVVLktstgyLVRYVPVISGEALAHAYQASLVDIAKKE--GLPVGNLSSQYEF 81  Sulfolobus solfata...
NP_126705   7 GVRFEANVEALNMVETAG-NYTKHRRVPYLVeedgklKTIYVPAISGESLAHAYQEHLVKEALRM--NLPVCEDCHRGEF 83  Pyrococcus abyssi GE5
NP_070696  12 RGRVMLNVEAMNMTESVG-NYVKHRRVPVVLpda-kyTTYFVPAISGESIAHGFQEVLAEVGKKN--GLKVCKLCEKGIF 87  Archaeoglobus fulg...
NP_147811   7 AGRVRVNVAVLTGHGTAG-NYSMHARARVYCcgd-ssKVYEVPVLTGNSLKHWHAYYAAQVYQALg-GSMLNELCKRGIG 83  Aeropyrum pernix K1

AAL80766   86 TRFGQGETTATkangatvQLND-------EATIIKELADaDVHGFLAPKTG---RRRVSLVKASFILPtedfiKEVEGER 155 Pyrococcus furiosu...
BAB64980   87 IKRGAGDSVHKtgc-gdkNGSDy------ELCVIEEDIVeDVAGFLNPDKL---VKRTSNIAFSYMIPal-daVKASAVT 155 Sulfolobus tokodai...
AAL62629   81 LRGFTVDSTLKnp----kPVTD-------ECEALKDFCN-DLHGFLSPQEEk-pVKRDSLVKISFAVPvl--eEGNLKAV 145 Pyrobaculum aeroph...
NP_343397  82 IKFSTDEALKIeg---ikEPKDyndarrfEVEVMLKDVIaDVGGFMYAGSAp--VRRTSRIKLGYMIPalrgdEIPAQLE 156 Sulfolobus solfata...
NP_126705  84 YKSMNKVHLQKki---spIPNDpr---kiEEAIIRKCVVeDVGGFLYAEKPp--VRRSSTFQVSYALPik-smALFATAE 154 Pyrococcus abyssi GE5
NP_070696  88 LKSTNENVFKEsfs--sdPPKDdf---efEKTVIENCIVeDVGGFLYAPRAggnVKRTSNFYTGYMIPvr-esIEGAVIE 161 Archaeoglobus fulg...
NP_147811  84 LRGYNVDTNLEge---rrLATR-------ESEAIKDFCN-DLHGFLIAERGr-qLKRDSLARFSFAIPvl--nNEVLENI 149 Aeropyrum pernix K1

AAL80766  156 LITAIKHNRVDVdekgai-----gsskeGTAQMLFSREYATGLYGFSIVLDLGLVGIPQGLPVKfeenqprpnividpnE 230 Pyrococcus furiosu...
BAB64980  156 SQFHVRYATKEMidky--------ekenKNIQSLYNVETASASYVLTGYLNLSNIGVTQNYPVKev------------kD 215 Sulfolobus tokodai...
AAL62629  146 AKFAVQHNRVVPptvnv-------kqkeGEGMMLFKQEYGTGLYAFALRMDLAHIGNPLFDECNaef---------qsdE 209 Pyrobaculum aeroph...
NP_343397 157 AQFHVRFSNKPV----------------KGSQAIFNVEVSSALYTFSFELDEDLIAVPSTVGEKvkgee------elerQ 214 Sulfolobus solfata...
NP_126705 155 PQLHARHAQLDTssk----------kgnVSEQMIYYVETGTALYGFVFNLDLDGIGVSAITSEPvlg----------eeE 214 Pyrococcus abyssi GE5
NP_070696 162 PQLHSRYALGTPfv------------egGQGQMIYYVELSSAVYTFSFDLDTRYIGRTTFSYEKagt---------evgK 220 Archaeoglobus fulg...
NP_147811 150 EKFSVTHNRVDPlqrrrageesnsqetgATEMMVFKQEYSSGLYGISASFDLEYLCRPLYESEEggsa-------cdeeE 222 Aeropyrum pernix K1

AAL80766  231 RKARIESALKALIPMLSGy-IGANLARSFPVFKVEELVAIASEGPIPa--LVHGFYEDYIEANRSIIK 295 Pyrococcus furiosus DSM 3638
BAB64980  216 KKDREIASLDALMLTLTQflFGAKRTRFNPLVEIEALVLSVSEKPFNl-pPINGDFNDYLNLVKSTAD 282 Sulfolobus tokodaii str. 7
AAL62629  210 RKRRAKASVLALLPLLTG--AGSKQARALPIVAVREVLVAVSEKPMPn--LIHAVYPDYCETSIDTVG 273 Pyrobaculum aerophilum str. IM2
NP_343397 215 KARRVDSAIKALYSLLAGn-FGGKRSRFLPSMKLMSLVVVKTDFPFIpepGHDDSYIKTTVMRLEKAK 281 Sulfolobus solfataricus P2
NP_126705 215 IKKRREAALMALFRMLSSaqFGAKLSRFFPVGGITELVVSVTEHPFVvtsPIYEGYAEKTEKRLEVLK 282 Pyrococcus abyssi GE5
NP_070696 221 RSERINAALEALKKFLIEfaFGAKKTRFLPVMEWDSLVVAVSDDVWTvpsPYTAGYIDNARKKKEKVN 288 Archaeoglobus fulgidus DSM 4304
NP_147811 223 RMRRARASLLALAYLLGG--AASKQARALPIAMVEELVVAVCNKPVPn--AVHGSYENYVEKTASLLK 286 Aeropyrum pernix K1
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