Conserved Protein Domain Family
Cas8a1_I-A
?
cd09672: Cas8a1_I-A 
CRISPR/Cas system-associated protein Cas8a1
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as TM1802 family
Links
?
Statistics
?
PSSM-Id: 187803
Aligned: 4 rows
Threshold Bit Score: 554.46
Created: 5-Feb-2010
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
NP_229599      1 MLEKIYNLGKIGGDSf-------------SNFAEEV-PSDEGIAIFLESNSEGLVfkdvvsIEKKPGGKn---sKIFLYR 63  Thermotoga mari...
AAM30260       1 MIETICDIGKIVRKTdgei-------dlvDLWQKEE-SGDYQLILDVNISDDSVR------INSRDFEK-----KVFRDG 61  Methanosarcina ...
YP_002728850   1 MIEAVRNLGEFVLQQenk--------seiDILLENPnSGNYNKVIVLNFNKDFTFs----nITTEDFKKdn--wRVYLYR 66  Sulfurihydrogen...
YP_002250042   1 MLTNIKEIGKMVRTTsaedfvsnlveydeDLMVDEKeNRKFLVIMDFDLESEKIN------LYRREVDRqvleeYLWVGN 74  Dictyoglomus th...

NP_229599     64 KQrGNFSSSVSP----TMKFLDKSSGSRDPLERTFDVFLGffDHPKISHIKDVLERNK--EEIIDKLRNYDVKNRf---L 134 Thermotoga mari...
AAM30260      62 LL-YSQGNWFVGa---VLKKESLKDSKIKDCLKFIDVPLD--RFDEVKSLIDLSLKDY--DGVNFVILFWKNGQKp---I 130 Methanosarcina ...
YP_002728850  67 RK-SSNGPDFTP----TARVTEPKKTIENKIIKWFEEHRN--ENQILKKMYEELIKNK--NDILNEVEKRKSSKDegivL 137 Sulfurihydrogen...
YP_002250042  75 AK-GNNPQDRLTtnnvSYLICSAGAGNGSSIVNLLNNLKGgtLKNLLEEVKNKFFMSLplEKVRYCLDLSKIGNGe--iI 151 Dictyoglomus th...

NP_229599    135 TISIDg-----KFPAEVPeilq-----afedKVTQKKTKg-----------------------------------EAKCF 169 Thermotoga mari...
AAM30260     131 EIVKN------KFLREIE-------------KNGLKKEKl-----------------------------------SGNCQ 156 Methanosarcina ...
YP_002728850 138 TVKIDg-----KYLYEIDnpnfk----eifiKDFYKRLKdtk-------------------------------skNACCS 177 Sulfurihydrogen...
YP_002250042 152 DIKPPessdekKYLKDIEnlwkkkfleiieeKLGLKEKEislftvtingmkpsefkdykeyienslieesfeesfEGTCH 231 Dictyoglomus th...

NP_229599    170 LCGKEANSRL---SDVFKFATFDKPGFTPf-------lSKKHPIQICDDCRSVLEKARRAIDEKLSFSFFSNNRILWIIP 239 Thermotoga mari...
AAM30260     157 ICNEYTDTLYd--SIVYKCYTNDKEIFSN---------TDGISYGICKDCIFDVLYGRKHVNMFLSTWWGGSEILFLPHT 225 Methanosarcina ...
YP_002728850 178 LCGEVKDEVFt-tSEIYKFYTLDKPGYIAggf---nksNAWKNFPVCESCYLKVDYGRKYIEEHLEFNFYGKTYYIIPNV 253 Sulfurihydrogen...
YP_002250042 232 VCGERSEITYdttKFPVKFYITKLITFSSdfegkgvkkGFSKNFSLCRDCYKDIILGIKFIQNNLDTRLGNNDLWIIPGL 311 Dictyoglomus th...

NP_229599    240 SVP--DQDILESVIEKIYEIKDTDKn----SKFRSfaRLEEEIEKVLSe---NERAVYDFVLIEKEQQAERIVLHVEEVS 310 Thermotoga mari...
AAM30260     226 YNE--EVKEIFEFSKIGDLREGKNL-----LQQIR--ENECDVINEIG----KCGTDVDILFYSAQKSEWKITYNIKDVI 292 Methanosarcina ...
YP_002728850 254 ILN--TKEVMNEYLDILSEAKKRVS-----LKDKNptEDENYIINLLKd--hKDGLCFYFLFLKKENSAERILLLIEDVL 324 Sulfurihydrogen...
YP_002250042 312 FFNplGKELKESWIRTSREFVKSTFnlqefLSFEE--RIQRNLDEYREfeeiADYGTVDLLFYERSKEAFKIKEYIKDVH 389 Dictyoglomus th...

NP_229599    311 PTRVRRILEESKKIEs---QLKE--DGFkv--svNFSVIHKFFEDLDRYFNS--------LFSAVFSEGTFDKKLLLTLF 375 Thermotoga mari...
AAM30260     293 PSRFSKIAELEHKYQ----SKSG--ENLa-----LWQVLAYLLGNSSKPSEIfntneaknFLKNIFHGNKINRNLFFSRS 361 Methanosarcina ...
YP_002728850 325 PSRISKIFKVKKEVE----KIFNi-ENY------NFGFLTQFLGNYDKIFFE--------VIDKIFRGGKLDFQTLLQIF 385 Sulfurihydrogen...
YP_002250042 390 LRRVEKIRNSIREVEnlgrEIFGegENWflgledIYFLIPIRRGKVSEYKKMl------dLYEDIFLEHRIDKDILIDYF 463 Dictyoglomus th...

NP_229599    376 LSKIRSDFFGN----DTLLSAREAFAT---YVYLRRLNVl-------KGGASVLKGE------DFFSRYPEFFDEPWKKA 435 Thermotoga mari...
AAM30260     362 MSKYKHDYFEGy---ENMFMLHRTYNF---LVDCGCLDKgwcfveqtSRGYSMVKYEdl---eEFFDFNKGFFDSNIKKA 432 Methanosarcina ...
YP_002728850 386 TKKIRDEFLSGnsitNTVIYALMNVRF---FEELGLLESk-------EGKMEKTKFD------EIYEKVGKSLNTPAKRG 449 Sulfurihydrogen...
YP_002250042 464 VDLAKVYRFEKfsqyNIKMVKNTDMGMslsILKTNLLLKlfeklnliTGGDRMPEFAddvldkDLQEYISKMQYSEEEAA 543 Dictyoglomus th...

NP_229599    436 VFLEGVLANYLLYLQYVKRNSKAFTKk--------LKGLRLTKRDVEGLLPEIRAKIEA--YGGMSESVAELFRETAEAF 505 Thermotoga mari...
AAM30260     433 WFLLGRLYGKMIQESKSYKGGEDKQSneshleknfFFGRKYDFKTFVYFSNQCSELMYK--YGVQNKGYLKDLISTSKEL 510 Methanosarcina ...
YP_002728850 450 IFLLGALTQMLLDIQWSERKTTPFFKn--------LKGLKMNEEDIKGLLPKVVNKLME--YERYDKGKQELAQEISKNL 519 Sulfurihydrogen...
YP_002250042 544 LFLLGYLIGEIGYEQIRGADLSAKKPil-----nkINFNGISAKNLINLANEVFEKLDQykIRGYNEKTFSVMKSLMDKH 618 Dictyoglomus th...

NP_229599    506 LEAGNwsASPDEISFVFVSGLSLGK 530 Thermotoga maritima MSB8
AAM30260     511 MGAGDskLSSDEAKYIFFWGMQQWI 535 Methanosarcina mazei Go1
YP_002728850 520 LSQEKfgLSINEINFYFVSGMALSE 544 Sulfurihydrogenibium azorense Az-Fu1
YP_002250042 619 IKSWK--LSEQENVYYILSGYAFNT 641 Dictyoglomus thermophilum H-6-12
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap