Conserved Protein Domain Family
Csm4_III-A
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cd09663: Csm4_III-A 
CRISPR/Cas system-associated RAMP superfamily protein Csm4
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein
Links
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Statistics
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PSSM-Id: 187794
Aligned: 7 rows
Threshold Bit Score: 270.858
Created: 5-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
O27151      2 LVYLKPESSLPp-------------LSSDTIFGALIYSFSQLYPde-vDEVVDQFMEdppFLISSSFPYietdeRLRFYP 67  Methanothermobacte...
Q97CJ3      3 LFKISFKSSSSy-------------VDSIKISRAIIYAYNTLYPdk-iDDLINKVKDs-yVSVSDLLLYk----NKVYYP 63  Thermoplasma volca...
NP_616858   7 IVKLDFTSPLHigevgigleenslvLHSDTIFNAICNSLAKLYGrewvTKFLQNFSEnvpFRISSGFPFi---kETLYFP 83  Methanosarcina ace...
NP_229605   7 LVKMSFRSGFRvg----------rgNETDSTLPTIHSDTIYGAVvyhaFKWSEKAEDfakKLKVSSLLFvr--gDRLLVP 74  Thermotoga maritim...
NP_217336   5 LFRFDFDRTHFgdhgle---sstisCPADTLYSALCVEALRMGG----QQLLGELVAcstLRLTDLLPYv---gPDYLVP 74  Mycobacterium tube...
NP_248678   5 VLKPKINSKFHfgegsl--ernskiFHSNSLFSAIVNNYIKLYGredlEKNIEKIKN---IRLSSLLYKi---kNIYLIP 76  Methanocaldococcus...
BAA29235    1 MVKLKPKGPFTr------------iPRATTIFGAISNAIRLLYGrkevEKFIAGFINd-dAKITSAFPYd---gETYFLP 64  Pyrococcus horikos...

O27151     68 RIITEPGSYDPILFKk------YKGVSYIPEGLFLEWASGEADEEHIVnsmeknrvyggl------------------li 123 Methanothermobacte...
Q97CJ3     64 FPPINALIDVNNTESik---nrKKRSEFIDIDELSSIVEAFKETGYQGvnyskikheg---------------------- 118 Thermoplasma volca...
NP_616858  84 KPMNQANIEENLLQDys---kkLKKTTYLTQKFFEKWIAEERLFKKDLnaiteskttksedseelsktdineikdnknta 160 Methanosarcina ace...
NP_229605  75 KPFLYNTYSLEEDDEesp--keLKKASYVFLDKLADYRSIKEASGAVCken----------------------------- 123 Thermotoga maritim...
NP_217336  75 KPLHSVRSDGSSMQKk-----lAKKIGFLPAAQLGSFLDGTADLKELAarqt---------------------------- 121 Mycobacterium tube...
NP_248678  77 KPEHPEFYKLKGNPGikp--kdIKKIQFFSIKAYKELLDNELDWKNKIkhivdyqtinksivisekeieeikrifgikae 154 Methanocaldococcus...
BAA29235   65 KPLSVDLVVKTLFETkkedvkkVKKKDYIPLESFEKALRLEEFEVKELp------------------------------- 113 Pyrococcus horikos...

O27151    124 dgdkdirfgeVEFEEPHNVVNRI-------ERRTEGVFHLRRVFYENMGRFFLVKFRda--sFRSRLESALRFLAdrGLG 194 Methanothermobacte...
Q97CJ3    119 ngdnkgkphkILISEPGINIFQTp------EIKDNKYKYNDIFTKELFIYDESCFYAr---nSDKNIEATINLLNdfGLS 189 Thermoplasma volca...
NP_616858 161 vrgdifsefkKDLLLPKVSVSRE-------NAESSIYFLGSIRFNEDSGIWFILDCDde--dCEKKVISALRLLQhdGIG 231 Methanosarcina ace...
NP_229605 124 --------pvEIVRIPRNSLDRI-------TSSSNLYFVEVAFVKEGFTPAFLAEFPd---eYEGLFKTAVKSLGdsGIG 185 Thermotoga maritim...
NP_217336 122 -------kigVHAVSAKAAIHNG-------KKDADPYRVGYFRFELDAGLWLLATGSe---sELGLLTRLLKGIS--ALG 182 Mycobacterium tube...
NP_248678 155 klkhakisliSKHLEQKVAIDRLkditlekDDKGQLYNIEFIKLNENVEFYFLIDYNnedkeFIKKLEASIKLIEdeGLG 234 Methanocaldococcus...
BAA29235  114 ---------yKVIELPKVSLDRV-------SNDSSLYFWDLVTFKENSGLYFLYDGSnk--lFEKYIVPAMRLLEdqGIG 175 Pyrococcus horikos...

O27151    195 PDVSTGKGTFS-FEFDRn--PLPEYTGER--------FVTLSRFIPaps-eleSVTRDAWFELgsrrGRGPDG------- 255 Methanothermobacte...
Q97CJ3    190 GRRSTGKGEVYiEKINDn--FNEGFNGEGi-------YILLSSFIPdndyiknIDFERSRYNIktlqGKNING------- 253 Thermoplasma volca...
NP_616858 232 GKRTWGYGNFS-MEVKNi--ELKVPDSKT--------YLLLSLFYPkdd-eneNESGLFSSERar-wGFSLRGgyaypyg 298 Methanosarcina ace...
NP_229605 186 ADSTYGYGLFN-AEFESa--PDFPEEGEY--------YLTLSLFVPsae--erSKMNEGYYRVvkrrGVKRDEm------ 246 Thermotoga maritim...
NP_217336 183 GERTSGFGAFNlTESEAp-aALTPTVDAAs-------LMTLTTSLPtdd-eleAALAGATYRLvkrsGFVASStya---- 249 Mycobacterium tube...
NP_248678 235 GKRSIGAGFFEkVEIVDlpeDFNEILDENskynnleyKMLLGVGIPn-----kDDIKNIEYYKlieiGGYIYSlec---- 305 Methanocaldococcus...
BAA29235  176 GKGTWGYGLFE-VEIEEl--EIEEPRENS--------YVTLSPFVPe------NETSLILWKIvk-lGGWSQG------- 230 Pyrococcus horikos...

O27151    256 ----EIRKQVRFFREGSTFNDT--GKEYYGTLVRSg--------------rSAVEYGLAYKFM 298 Methanothermobacter thermautotrophi...
Q97CJ3    254 ----NPIGPFRYFAPGSIFYLK--GDVKGVSFIENn---------------GIIPFNPVITKV 295 Thermoplasma volcanium
NP_616858 299 skssFHKPQRLFIKEGSIFEKApkGKLIKDATNLDgl-------------eKLYHYGLAYSIP 348 Methanosarcina acetivorans C2A
NP_229605 247 ----KVKKEISYVQEGSVFPFKpeGRGVLKIEDYFvq-------------tSPLCVAFGGDGK 292 Thermotoga maritima MSB8
NP_217336 250 -dmpLRKRDIYKFAAGSVFSRPfqGGILDVSLGGNh---------------PVYSYARPLFLA 296 Mycobacterium tuberculosis H37Rv
NP_248678 306 --ltKPKRNILALTEGSIVKNDfiGDVKDISPQNDddeqnknnennnklnhKVYTHGKPILLP 366 Methanocaldococcus jannaschii DSM 2661
BAA29235  231 ----KRRPKIPMVVEGSLSREDr-GKMITLDLSLSyp-------------vYVYARSFLVRAS 275 Pyrococcus horikoshii OT3
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