Conserved Protein Domain Family
Csm5_III-A
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cd09662: Csm5_III-A 
CRISPR/Cas system-associated RAMP superfamily protein Csm5
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein
Links
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Statistics
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PSSM-Id: 187793
Aligned: 7 rows
Threshold Bit Score: 337.907
Created: 5-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
NP_616859   3 CKIELLSPLHIGNGNElkmvdfy---------lnekkdEIRFIDFEKFIDYCIEKRINLNQEMKn--pRYYTGSDFSISK 71  Methanosarcina ace...
NP_142168  17 AMFEVLTPLHIGNGNEltpvdf-----------yplgdRIIVLDTEKLINDLLRLGVEVEELLDf--lRNPPGSLYLWRG 83  Pyrococcus horikos...
NP_217335  10 LTLRCLGPVFIGSGEKrtskey-----------hvegdRVYFPDMELLYADIPAHKRKSFEAFVm--nTDGAQATAPLKE 76  Mycobacterium tube...
NP_229604   3 VTLKTLTPLHIGSGEKyppcnlvv-------lkeeenkKTAVRLITRKFLEVLRKHPEIKQNISe--nISKPLSFKEVEN 73  Thermotoga maritim...
NP_248677  48 VKCELITPIFIGCGEEysqldy-----------fiedgLAHIIDLEKAVSDLDDLEKVDYISGLivsnIDNNRLNLTAKD 116 Methanocaldococcus...
NP_110627   3 VQLKVSSPVLIGNDYVnvtnmiinkdslymldmdklidNEPKIDQLAEYFLSYKSSDKDEYSKYneikRFYNNINAENYK 82  Thermoplasma volca...
NP_614602   9 VRLEVLTPLHVGVPREeelvrgl--------dyrvdgnRILVVDFTTLPPERAERVLGALEGGD----HAEAEGYLEGAE 76  Methanopyrus kandl...

NP_616859  72 FMD--AKQIDPNTFTSYAVSaiigkrnresef---------------aikefvkcggpYLPGSSIKGSIRTALMWNCLNE 134 Methanosarcina ace...
NP_142168  84 YLE--KLHLDPRNYARYSLRirgelgressr----------------ikefikikgkpYIPGTSLKGAIRTAVLYKVLKD 145 Pyrococcus horikos...
NP_217335  77 WVEpnAVKLDPAKHRGYEVKigsieprrasrgrggrmtrkkltlneihafikdplgrpYVPGSTVKGMLRSIYLQSLVHK 156 Mycobacterium tube...
NP_229604  74 VED--GVFYEVSLYSDFSSGkknpeipev---------------------vhhpdgsvYVPGSSLKGAVRLALTWHVLRN 130 Thermotoga maritim...
NP_248677 117 ILE--SVGLNPYDYVIRKIEseifsnkktrv-----------------kkfinqnntyYIPGSSIKGAIRTAYIFNYYDK 177 Methanocaldococcus...
NP_110627  83 IEP--EIKGDKEFYEVINSNdnkflkakdvkltm----------gtyevinnkktfvpFIPGSTIKGAIRNAIRNEYIKK 150 Thermoplasma volca...
NP_614602  77 VLR--EVELRTGGVPDRFLPtyrpt----------------------------rvddpWIPGTSVKGALRTGLLLAALKR 126 Methanopyrus kandl...

NP_616859 135 Rpdgmeivq----------------------nglqkwlDKSRIAARDLKMLDENISEVIFgkd--------prSDILRVL 184 Methanosarcina ace...
NP_142168 146 CgdvptvvealgkygkttgniiraithpgnqdlldyylFYLGRGNVRGKQADDILEAIVFgfeaerrfryepkRDPMKAL 225 Pyrococcus horikos...
NP_217335 157 Rtaqpvrvp----------------------ghqtrehRQYGERFERKELRKSGRPNTRPqd---------avNDLFQAI 205 Mycobacterium tube...
NP_229604 131 Nrnlleefr----------------------rnvqkdlQNHKRAFYQTNEFLNGLFRFAPke---------inTDYFRFL 179 Thermotoga maritim...
NP_248677 178 Nlpell---------------------------kilddRNIKLHDKGKELEKNAISKDIP-------------KDFFKYL 217 Methanocaldococcus...
NP_110627 151 Nkinityddhk------------------kvksynfngNSYGDLDEAIFYKEDQKRQNEPkk---------isNDVFRFV 203 Thermoplasma volca...
NP_614602 127 Ldglgtdlstltdrlprn----pkkaavaldnrlratvFQGGTARRSYRRKPNRGWPEVFp-----------hADVLRAL 191 Methanopyrus kandl...

NP_616859 185 KPSDTNLVSKs--RLEVSEIKIVGNSQei----pVYVENLKTGtELSFDVAFDNYLITQDQNEPKFKnhpcvrymnvqai 258 Methanosarcina ace...
NP_142168 226 IVRDSRLIPLd--NLSVYEVRVVGWGSsi----pIWVEALDPGtRFEAEVKVDRELLRIGSDYFNGLlwhcl-------- 291 Pyrococcus horikos...
NP_217335 206 RVTDSPALRTs-dLLICQKMDMNVHGKpdg--lpLFRECLAPGtSISHRVVVDTSPTARGGWREGERflet--------- 273 Mycobacterium tube...
NP_229604 180 RVSDSQTLRT---QLVVHDVGIFYVARpnthprtFPLEFVPINrDFVFDVRFVKEEYDYFLTHVRKRygvelpgsieeif 256 Thermotoga maritim...
NP_248677 218 KISDSLNLEGe--FKFIHTKRWNYRKKkfd--vpINMEGMTKG-TFSINIKIEDEFFKNINKRLKTNynpkddekkfdil 292 Methanocaldococcus...
NP_110627 204 EVDDFYPKEYslkIYRIERIKLSNNKRng---ipFYAISIDSG-TFTGNIKIGRSFDNIYKSDKNQFyaiskvfnklidi 279 Thermoplasma volca...
NP_614602 192 KVEDARPVGKi--RTAVYRAELHPKGRp-----lDAREFVVSG-TFELELGTDHGELKRVLDTWDRVelprlp------- 256 Methanopyrus kandl...

NP_616859 259 ckac-----nefskkviekhleylwENYNCDEAAEEFDSLWnkvlscngneAILHIGWGGGWYSTTIGLIIETLPGFstc 333 Methanosarcina ace...
NP_142168 292 ---------------------agedFEEFVWKAVEEFYGELakldn-vkerDVIRLGWGSGWISMTVGILLMRKRGWerv 349 Pyrococcus horikos...
NP_217335 274 ---------------------laetAASVNQARYAEYRAMYpgvn--aivgPIVYLGGGAGYRSKTFVTDQDDMAKVlda 330 Mycobacterium tube...
NP_229604 257 sivnefysevfkfererfkkakenfEKLDTSKIEERFQKIEkvlq--skkyVLIHIGYGGGLMANSLFILLDEETRKqvr 334 Thermotoga maritim...
NP_248677 293 kn---------lcnnfsktvvefelKKNNPVYVEKSYEKLLadin--kddaIYLNLGFGGGFLNKTVYPLLWKNDENhly 361 Methanocaldococcus...
NP_110627 280 ki---------ndasdhtkneiinkMLCISGKYYRDILKKEkehyndnpdkEVLLIGFGGGIEEKTIINSLDDEQFKk-- 348 Thermoplasma volca...
NP_614602 257 --------------------kpvfrFLRDVRSGLRDFWEETlenp--etvlERAREGWREGLRALSERFRVDVPDDAdvq 314 Methanopyrus kandl...

NP_616859 334 lvgnpknwklenttirnSFGLGKKPGTNKFSIN-----FPKTKRVTLeg----kPLGWVKL 385 Methanosarcina acetivorans C2A
NP_142168 350 ---------------rrKLGLGKNPHTNKIVER-----FPKTKRLANg-----qPMGWIKI 385 Pyrococcus horikoshii OT3
NP_217335 331 qf----------gkvvkHVDKTRELRVSPLVLK-----RTKIDNICY-------EMGQCEL 369 Mycobacterium tuberculosis H37Rv
NP_229604 335 n-------------iikYHKDDEAPLTRRYLVQs----ENNSYRVIS-------PIGWCAL 371 Thermotoga maritima MSB8
NP_248677 362 frk--------ikslfiALSGGNKNLKNAWLKAnsyldFPTTKTVYVknnsaiaPLGWIKM 414 Methanocaldococcus jannaschii DSM 2661
NP_110627 349 ----------------aEHIIKISNKKIKFSGR-----MPSTAWTINn-----kKFGVLEV 383 Thermoplasma volcanium GSS1
NP_614602 315 lgwg------ggrlvktALPLAGRVLRGPLDQF-----APQTVKLVDg-----eVPGLVRV 359 Methanopyrus kandleri AV19
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