Conserved Protein Domain Family
Cas5_I-A
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cd09649: Cas5_I-A 
CRISPR/Cas system-associated RAMP superfamily protein Cas5
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex
Links
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Statistics
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PSSM-Id: 187780
Aligned: 23 rows
Threshold Bit Score: 81.258
Created: 11-Jan-2011
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q57827         2 IMEALVAl-lRFPFYSFGkqsyqVRQSLLLPSPSALKGALAKGiillGGKKGKSLDEIAKktveelen---------kli 71  Methanocaldococ...
Q97YC6         2 KGVVIFGi-hHWGFSVRVprtsaGGSSYIVPPITTILGALSRGycsdYAVKNNVSCTKEFidkfssd-----------lf 69  Sulfolobus solf...
Q977B3         2 KGVLIYGl-hHWGFSIRVpkasaGGKSFPYVPISTILGALSKSycenYAVKNGTSCTKEFidkykgs-----------lf 69  Sulfolobus toko...
Q8U334         1 MDILLVCl--RFPFFSVAkrsyqVRTSFLLPPPSALKGALAKGlillKPEKYASSSLDEAalkaike-----------ie 67  Pyrococcus furi...
AAL80765       1 MDILLVCl--RFPFFSVAkrsyqVRTSFLLPPPSALKGALAKGlillKPEKYASSSLDEAalkaike-----------ie 67  Pyrococcus furi...
Q9YCM4         5 DWVVVAEl-aTPAFSVKNpesyqVASPLPLPLPSTLLGGLMRGasllGSCTGGIASQSCIkktgrivk----------aa 73  Aeropyrum pernix
NP_147810      5 DWVVVAEl-aTPAFSVKNpesyqVASPLPLPLPSTLLGGLMRGasllGSCTGGIASQSCIkktgrivk----------aa 73  Aeropyrum perni...
YP_001012845   4 LMLVSKVe-lAWGFSVRYagasaAQPALPIPPPTTIVGFYAEPla-rLLGLAEYRGFPAKrpcs---------------- 65  Hyperthermus bu...
YP_001435723   1 MMGLFFElelAWGFSVRYpmssaAQLAPPLPPPSTAIGALAEAla-iTLGLGETIKVAGKaakrgrkrskeglcstayav 79  Ignicoccus hosp...
Q8ZZL1         1 MNILLVKl-rLPLFSIKHyetyqVAATLPFIPPSTVVGALVQAaargGLCEGDCLAEVRGwi------------------ 61  Pyrobaculum aer...

Q57827        72 yvgakPYKSSIIKTPILLKRLrnledqknpeksdamr-------------------------------reyvfareilai 120 Methanocaldococ...
Q97YC6        70 wvtygTEEHMLMPYSDLLREErvpyrqsknrsldhvsdw--------------------------fgvsafgkvycenvn 123 Sulfolobus solf...
Q977B3        70 wvaygADESRLLPYSDIMREQrvsykqkkyrsaeklrdw---------------------------fgvsafgktygesv 122 Sulfolobus toko...
Q8U334        68 sklvdIKAVSVAPLSPLIRNAfllkrlrnlesgsnaeks--------------------------damrreytftrellv 121 Pyrococcus furi...
AAL80765      68 sklvdIKAVSVAPLSPLIRNAfllkrlrnlesgsnaeks--------------------------damrreytftrellv 121 Pyrococcus furi...
Q9YCM4        74 aplskPGQILGVEWEVVLRRLrkvlepdseegstrenrgnrvld----------------elsrisdallrgyitpynpv 137 Aeropyrum pernix
NP_147810     74 aplskPGQILGVEWEVVLRRLrkvlepdseegstrenrgnrvld----------------elsrisdallrgyitpynpv 137 Aeropyrum perni...
YP_001012845  66 -paalLAEHTLAASAGLNSDSrsglvvhsdlshvatlpyqrrrktgwekl-----afaaqavgaaygpaarlylalvvdv 139 Hyperthermus bu...
YP_001435723  80 fkatkGAAFALSPESPVGVALkseinrllqapylnpgnvhegdeinkvrmfgvqaitsayapkgllwmmvvldekelvge 159 Ignicoccus hosp...
Q8ZZL1        62 ----yKARDVAAPTVKFPVVLkrargvleegklplsgeelg-----------------------gyfdamvreyayvaek 114 Pyrobaculum aer...

Q57827       121 yvfRRKLSEEEKDLMLKavYLIDQLGDTECVGNVIKTEwvev-------------------------------------- 162 Methanocaldococ...
Q97YC6       124 fsiLLLLNKENSEFWSKlgWQIISLGTKESLVTITDVKvvdve------------------------------------- 166 Sulfolobus solf...
Q977B3       123 kfsIAVLLKDKVEDFVKysWQIISLGSKESLVTIEHVEvvdve------------------------------------- 165 Sulfolobus toko...
Q8U334       122 ayiFKNLTQEEKNLYLKaaMLIDVIGDTESLATPVWASfvkpedkkaplafsapyteiysllsskiqakgkirmyiekmr 201 Pyrococcus furi...
AAL80765     122 ayiFKNLTQEEKNLYLKaaMLIDVIGDTESLATPVWASfvkpedkkaplafsapyteiysllsskiqakgkirmyiekmr 201 Pyrococcus furi...
Q9YCM4       138 yavFVARGRDNANRIEKalWYIDRLGDSESLVSARPVGrcqlaefrsks-----------------------------vn 188 Aeropyrum pernix
NP_147810    138 yavFVARGRDNANRIEKalWYIDRLGDSESLVSARPVGrcqlaefrsks-----------------------------vn 188 Aeropyrum perni...
YP_001012845 140 eglSRKLGETVESIISAlaWAGWRLGSKEGLVSVIHAEavepv------------------------------------- 182 Hyperthermus bu...
YP_001435723 160 lraIRKDLKGEEVMDALerVTIRRIGVKEGIVSTKKKEvgev-------------------------------------- 201 Ignicoccus hosp...
Q8ZZL1       115 avlVVPSAEAHIGRLEKalWLLERVGDTESYVSVRGVEvlnarpcgagevdvavklakvag------gahlvvragdedg 188 Pyrobaculum aer...

Q57827       163 -----keekAPLKTYVKFK 176 Methanocaldococcus jannaschii
Q97YC6       167 -----essdEDIYTIYYIP 180 Sulfolobus solfataricus
Q977B3       166 -----eseeEQFSTSFFIP 179 Sulfolobus tokodaii
Q8U334       202 vspeysktkGPQEEIFYLP 220 Pyrococcus furiosus
AAL80765     202 vspeysktkGPQEEIFYLP 220 Pyrococcus furiosus DSM 3638
Q9YCM4       189 tpvaldsavGGSFTVVYAP 207 Aeropyrum pernix
NP_147810    189 tpvaldsavGGSFTVVYAP 207 Aeropyrum pernix K1
YP_001012845 183 -----tltgGVFETILYQE 196 Hyperthermus butylicus DSM 5456
YP_001435723 202 ------tkeEEVESCFYAR 214 Ignicoccus hospitalis KIN4/I
Q8ZZL1       189 tlsdfavplATGGKGYYTP 207 Pyrobaculum aerophilum
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