Conserved Protein Domain Family
Cas2_I_II_III
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cd09638: Cas2_I_II_III 
CRISPR/Cas system-associated protein Cas2
CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold
Links
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Statistics
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PSSM-Id: 187769
Aligned: 11 rows
Threshold Bit Score: 76.2641
Created: 4-Feb-2010
Updated: 2-Oct-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
YP_190005      1 MYLLVSFDLprdtklerriASKYRLRLIELGfsMKQFSLYERYvsnvqKKDKILEILKQEIPDt--GSITLYilpdevnS 78  Staphylococcus ...
NP_217332     26 MFVLVIYDIsdn-----rrRASLAKILAGFGy-RVQESAFEAMlt-kgQLAKLVARIDRFAIDc--DNIRIYki---rgV 93  Mycobacterium t...
NP_110624      1 MYLIVVYDVde------srVNKVNKYLKRYLl-WRQNSVFEGEis-enLIDSMIKGITKIIKDe--DSIIIY-------K 63  Thermoplasma vo...
NP_687910      1 MRMILMFDMptetaeerkaYRKFRKFLLSEGfiMHQFSVYSKLllnntANNAMIGRLKVNNPKk--GNITLLtvt-ekqF 77  Streptococcus a...
YP_179675      7 MRVLLMFDVptkskkeqklASKFRNNLIKLGyfMLQFSVYMRIckglsSAKSSIENVKKILPPy--GNVRALiit-ekqF 83  Campylobacter j...
YP_001598554   7 MRIIVFFDLpvitaakrkaANQFRQFLLKDGyqMLQLSVYSRIvkgrdSLQKHHNRLCANLPQe--GSIRCLeit-ekqY 83  Neisseria menin...
NP_484426      3 KLYLVCYDIpdd-----krRTKLAKLIEQRCq-RVQYSVFECPleesvLNYQLEKRWLPILKLs-eDSLRVYpld-ataK 74  Nostoc sp. PCC ...
NP_070701      1 MLHLVVYDIsdd-----gsRARLAKLLEKFGlqRVQYSAFRGEln-pnDREVLARQVGKFVRDd-rDCIFIIplcqrcsS 73  Archaeoglobus f...
NP_241208      1 MLVLITYDVqtssmggtkrLRKVAKACQNYGq-RVQNSVFECIvd-stQLTSLKLELTSLIDEe-kDSLRIYrlg-nnyK 76  Bacillus halodu...
NP_558438      1 MYVVVAYDIted-----evRNKVADALKAYGleRIQRSVFVGRin-paLLKDLVERLKRITKGa-nADITIFkvdrraiD 73  Pyrobaculum aer...
NP_614593     10 RLRLYVYDFkepg--geaeRRKLRELLESHGafRLQYSTYALLae-peVHARVLRRVVARVDFeegDSLIVVpm----cR 82  Methanopyrus ka...

YP_190005     79 NQITILgkev---klaVNKEP 96  Staphylococcus epidermidis RP62A
NP_217332     94 AAVTFYgrg-----rlVSAEE 109 Mycobacterium tuberculosis H37Rv
NP_110624     64 FKVKSYidn-----iiIGNDK 79  Thermoplasma volcanium GSS1
NP_687910     78 ARMVYLhger--ntsvANSDS 96  Streptococcus agalactiae 2603V/R
YP_179675     84 DKMELLlggiv-fnekVNNET 103 Campylobacter jejuni RM1221
YP_001598554  84 AAMKLLlgelktqekkVNSDQ 104 Neisseria meningitidis 053442
NP_484426     75 QQTRVYgg-------ePPYEP 88  Nostoc sp. PCC 7120
NP_070701     74 TAIVISntg-----veLVKEK 89  Archaeoglobus fulgidus DSM 4304
NP_241208     77 TKVEHIgak-----psIDLED 92  Bacillus halodurans C-125
NP_558438     74 TAIRIGppp----parKNVDL 90  Pyrobaculum aerophilum str. IM2
NP_614593     83 RCLRVAr--------wVDAEG 95  Methanopyrus kandleri AV19
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