1V38


Conserved Protein Domain Family
SAM_SAMSN1
?
cd09561: SAM_SAMSN1 
Click on image for an interactive view with Cn3D
SAM domain of SAMSN1 subfamily
SAM (sterile alpha motif) domain of SAMSN1 (also known as HACS1 or NASH1) proteins is a predicted protein-protein interaction domain. Members of this group are putative signaling/adaptor proteins. They appear to mediate signal transduction in lymphoid tissues. Murine HACS1 protein likely plays a role in B cell activation and differentiation. Potential binding partners of HACS1 are SLAM, DEC205 and PIR-B receptors and also some unidentified tyrosine-phosphorylated proteins. Proteins of this group were found preferentially expressed in normal hematopietic tissues and in some malignancies including lymphoma, myeloid leukemia and myeloma.
Links
?
Statistics
?
PSSM-Id: 188960
Aligned: 4 rows
Threshold Bit Score: 90.6929
Created: 19-Oct-2010
Updated: 2-Oct-2020
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
1V38_A         8 RRENHQTIQEFLERIHLQEYTSTLLLNGYETLDDLKDIKESHLIELNIADPEDRARLLSAAESLLS 73  house mouse
Q9NSI8       239 NSKKSKTLQEFLERIHLQEYTSTLLLNGYETLEDLKDIKESHLIELNIENPDDRRRLLSAAENFLE 304 human
NP_001006256 238 KRNKPKTLQELLERVQFQEYTSTLLLNGYETLEDLKDLHESHLIELNISNPEDRARLLSAIENLQD 303 chicken
NP_001006039 228 RRPRPKTLQELLERLNLEEHISSLLLNGYQTVEDLRDLKEQHLVELNMTDPEHRHRLLAAAENLLD 293 zebrafish
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap