Conserved Protein Domain Family
START_ArGLABRA2_like

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cd08875: START_ArGLABRA2_like 
C-terminal lipid-binding START domain of the Arabidopsis homeobox protein GLABRA 2 and related proteins
This subfamily includes the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of the Arabidopsis homeobox protein GLABRA 2 and related proteins. The START domain family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. Most proteins in this subgroup contain an N-terminal homeobox DNA-binding domain, some contain a leucine zipper. ArGLABRA2 plays a role in the differentiation of hairless epidermal cells of the Arabidopsis root. It acts in a cell-position-dependent manner to suppress root hair formation in those cells.
Statistics
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PSSM-Id: 176884
View PSSM: cd08875
Aligned: 32 rows
Threshold Bit Score: 217.909
Threshold Setting Gi: 110349530
Created: 30-Jul-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative lipid
Feature 1:putative lipid binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                    ##            #                     # #             
BAD89977     252 KSRIAEISNRATLELQKMATSgePMWLRSVEtgre--ilnyDEYLKEFpqaqassfpgrktiEASRDAGIVFM-----DA 324 thale cress
XP_002446115 249 QVTLLSYAECAIKEFDILARNgpPLWLPIIGgnm----lniQEYTRLRfprlhgicpqgfvvEATRDTALVRG-----TA 319 sorghum
DAA05779     156 PVGLSALAEQSLADFLAKATGtaVDWIQLLGmkp-----gpDSFGIVAishg-------cdgIAARALGLVALeatrvSE 223 Selaginella moe...
BAG68821     210 TSIFLNLAITALRELITLGEVdcPFWMIDPIvrskgvskiyEKYRSSFnnvtkp---pgqivEASRAKGLVPM-----TC 281 thale cress
NP_001061465 260 MEEFFSLMKENESLLVKKKENg-PLWLPHMDilgve-slnyQEYLAKSrtigqk--pvdfkvVVTRDTAIVNG-----SC 330 Japanese rice
NP_195014    154 PAGLLSIADETLTEFISKATGtaVEWVQMPGmkp-----gpDSIGIVAishg-------ctgIAARACGLVGL-----DP 216 thale cress
ABG73246     160 PAGLLSIAEETLTEFLSKAKGnaVEWIQMPGmkp-----gpDAIGIVTishg-------ctgVAARACSLVGI-----DP 222 loblolly pine
BAA92366     198 PAGLLATAEETLTEFLAKATGtaVDWIQLPGmkp-----gpDAIGIIAishg-------cvgIAARACGLVAL-----DI 260 Physcomitrella ...
ABG73241      94 YAGVISLAEEALSDFLSKATGtsVNWIQMPGmk------pgPDFMSMVnimph-----gatgIGARACGLINL-----EP 157 Ceratopteris ri...
EAY76106     216 QQMIAELAKNAMHALIILAEShvALWFPVPGcayev-lnkmMAYDQAYpgdnsan-aigfktEATRAVSMVMM-----DY 288 Indian rice
Feature 1          #   #   #  ##    ##                             # ####  #  # # #              
BAD89977     325 HKLAQSFMDVGQWKEtfacLISKAATVDVIRqgegps--ridgaIQLMFGEMQLLTPVVPTREVYFVRSCRQlspeKWAI 402 thale cress
XP_002446115 320 SDLLGILTNVPRWFEtfpgIVAAVRDYHNVSsgifgsgngliqeLLQINVDLSVESPCPPLRSMKFLRISMQtangDFAV 399 sorghum
DAA05779     224 WRIVEVLKDKTSWLW----DCRRSDVIHICSsen-------gstMEIMHTQLYAPTTLAPPRDFCTLRLTTSledgNLVV 292 Selaginella moe...
BAG68821     282 VTLVKTLMDTGKWVNvfapIVPVASTHKVIStgsgg---tksgsLQQIQAEFQVISPLVPKRKVTFIRYCKEirqgLWVV 358 thale cress
NP_001061465 331 VDLVKSLLDANRWRElfpgIVASANTTKIIStgpsn---lhdglLQLMRAELQVMSPEVPVCDVTFLRQSVQfgsgLWCV 407 Japanese rice
NP_195014    217 TRVAEILKDKPCWLR----DCRSLDIVNVLStan-------ggtLELIYMQLYAPTTLAPARDFWMLRYTSVmedgSLVI 285 thale cress
ABG73246     223 TKVAEILKDRTSWLR----DCRSVDVLTAFStgn-------ggtIELLYMQMYAPTTLASARDFWTLRYTSVledgSLVV 291 loblolly pine
BAA92366     261 SKVTEVLKDRPRWLQ----DCRRMEILGALPtgn-------ggtIELLYTQMYAPTTLAPARDYCTLRYTTIledgNVVI 329 Physcomitrella ...
ABG73241     158 SKIVEVFKDKPTWLR----ECRRMTTMFSTSttg-------ggtIEVLYSQMYAPTTLAPAKDFCTLRYTTVsddgSYVV 226 Ceratopteris ri...
EAY76106     289 KSVVDFLMDPYNYRTffpeVISGAVTNRIYTwptsd---gyngvIQLMTVEMMFPSPLVPARKCTFLRYCNVlnegLVVV 365 Indian rice
Feature 1         #                             # #### #           # # # # # #       # ### ###  #
BAD89977     403 VDVSVSved-----------sntEKEaSLLKCRKLPSGCIIEDTsNGHSKVTWVEHLDVSAs--TVQPLFRSLVNTGLAF 469 thale cress
XP_002446115 400 VDVSINgvhe----------qeaGSKnKHTSCRLLPSGCLIQDMgDGHCQVTWIVHAEYNEt--IVPPIFRQFFGSGQAF 467 sorghum
DAA05779     293 CERSISdaec---------lsyvPSTqYFVRAEMLTSGYLVRPCeGGSCIVHIIDHLDLKPs--SVSEVLTRPLYRSSSL 361 Selaginella moe...
BAG68821     359 VDVTPTq---------------nPTLlPYGCSKRLPSGLIIDDLsNGYSQVTWIEQAEYNEs--HIHQLYQPLIGYGIGL 421 thale cress
NP_001061465 408 VDVSIDtilpgesktaqssvqtsSTAaRRMEVRLLPSGCVIEEMeNGYSKVTWMVHAAYDEr--AVPVLYHSLLRSAKAL 485 Japanese rice
NP_195014    286 CERSLNntqn---------gpsmPPSpHFVRAEILPSGYLIRPCeGGGSILHIVDHFDLEPwsvPEVLRSLYESSTLLAQ 356 thale cress
ABG73246     292 CERSLSgtqg---------gpsmPAVqQFVRAEMQPSGYLIRPCeGGGSLIHIVDHMDLEPwsvPEVLRPLYESSTVLAQ 362 loblolly pine
BAA92366     330 CERSLSgvqg---------gptmPPVqSFVRGEMYPSGYLIRPCdGGGCIIHVVDHYNNEPrsvPEVLRPLYESPAVLSQ 400 Physcomitrella ...
ABG73241     227 CERSLNgaqt---------vptaPQIsAFVRADMFTGGCLIRPCeTSGSIVVVVDHMDLESwsiPEVLRPLYESSTILAH 297 Ceratopteris ri...
EAY76106     366 IDVSLD-----------------DGS-IFSKCRKMPSGFLIQSIrPNSCKVTAIEHVLADD---TGVHELYQPCMNGLVF 424 Indian rice
Feature 1        #  #          
BAD89977     470 GARHWVATLQLHCE 483 thale cress
XP_002446115 468 GASRWLASLKRHCE 481 sorghum
DAA05779     362 LAQRMTVKALRFLK 375 Selaginella moellendorffii
BAG68821     422 GAKRWLATLQRHCE 435 thale cress
NP_001061465 486 GACRWVASLQRHSQ 499 Japanese rice
NP_195014    357 RTTMAALRYLRQIS 370 thale cress
ABG73246     363 KVTMSALRHLRQIA 376 loblolly pine
BAA92366     401 KSTLAALRHLRRLA 414 Physcomitrella patens
ABG73241     298 KVTIAALKHLRHIA 311 Ceratopteris richardii
EAY76106     425 GARRWVATMARQSA 438 Indian rice

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