1ZSW,3OAJ,4HUZ


Conserved Protein Domain Family
PcpA_N_like

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cd08346: PcpA_N_like 
Click on image for an interactive view with Cn3D
N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins.
The N-terminal domain of Sphingobium chlorophenolicum (formerly Sphingomonas chlorophenolica) 2,6-dichloro-p-hydroquinone1,2-dioxygenase (PcpA), and similar proteins. PcpA is a key enzyme in the pentachlorophenol (PCP) degradation pathway, catalyzing the conversion of 2,6-dichloro-p-hydroquinone to 2-chloromaleylacetate. This domain belongs to a conserved domain superfamily that is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases.
Statistics
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PSSM-Id: 319934
Aligned: 13 rows
Threshold Bit Score: 185.184
Created: 27-Jan-2010
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Zn binding site
Conserved site includes 2 residues -Click on image for an interactive view with Cn3D
Feature 1: Zn binding site [ion binding site], 2 residue positions
Conserved feature residue pattern:H [STAV]Click to see conserved feature residue pattern help
Evidence:
  • Comment:Zn(II) binding site
  • Structure:1ZSW_A; Zn(II) binding site of PcpA protein of Bacillus cereus.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1           # #                                                                          
1ZSW_A        30 GHHHISMVTKNANENNHFYKNVLGLRRVKMTVNqdd-psmYHLFYGDktgsPGTELSFFEIPlvgr-tyrgTNAITRIGL 107 Bacillus cereus
AAB81171       5 GLHHVTAFARDPQENLRFYTEVLGLRLVKKTVNfdd-pgtYHFYFGNqngdPGTIMTFFPFQgsgq-gtvgKGQAGRVYF 82  Bacillus subtil...
YP_001635217   6 GIHHVTAISARIQQNYDFYTRVLGMRLVKRTVNqdd-tsaYHLFYADgagsPGSDLTFFDWPlpre--rrgTHSIVRTGL 82  Chloroflexus au...
NP_386596      4 GIHHITLIARKVQANVDFYVGFLGLHLVKRTGGyed-pnqLHLFYGDaagsPGSLVSFLVWEdgsp-grvgYGQPSEIAF 81  Sinorhizobium m...
Q9WXE6        10 GLHHITVATGSAQGDVDLLVKTLGQRLVKKTMFydgarpvYHLYFGNelgePGTLYTTFPVRqagytgkrgAGQISAVSY 89  Sphingomonas pa...
NP_773604     39 GLHHVTAIIGDVRRAGGFYAGVLSLNRVKKTVCydd-pgsYHVYYGDdvgnPGTVMSTLAWNcvtp-gltgAGEVVQTAF 116 Bradyrhizobium ...
ABP93364      10 GLHHITVATGSAQGDVDLLVKTLGQWLVKKTMFydgarpvYHLYFGNelgePGTLYTTFPVRqagytgkrgAGQISAVSY 89  Pseudomonas aer...
AAK26513       6 GFHHLTVGVAGAQEDVDFYVKLLGQSLIKKTVLldgdepiYHLYYGNsrgdVGTLVTSFPFKqrgvkarpgSGQIRVINY 85  Pseudomonas putida
NP_814608      4 QFHHVSLLARHGQENQSFYTKLLGLRFVKNTVNqdn-nrmPHYFYGDyqgtPGSLVTFFIVPllgn-ryeeKNYLATIGL 81  Enterococcus fa...
NP_814418      4 QIHHISILNRLIKPTFDFYHNTLGLKLLMKTINqdd-htmYHLFFSDneqrTGTELTFFELNdgqd-qsfgTNTIERTIL 81  Enterococcus fa...
3OAJ_A         8 GIHHITAIVGHPQENTDFYAGVLGLRLVKQTVNfdd-pgtYHLYFGNeggkPGTIITFFPWAgarq-gvigDGQVGVTSY 85  Bacillus subtil...
4HUZ_A         8 SLHHITICTGTAQGDIDFFVKVMGQRFVKRTLFydgsipiYHLYFADelgtPGTVMTTFPTRrtgqkgrkgSNQFTVCTY 87  Sphingobium chl...
O34689         5 GIHHVSALTADAQKNLDFYKKVLGLKLVKKSVNqde-ptmYHLFYGDevanPGTELTFFEIPriap-fhagTNSISSIGL 82  Bacillus subtil...
Feature 1                                                        
1ZSW_A       108 LVPSedSLHYWKERFEKFDVKHSemtty-anrpALQFEDAEGLRLVLL 154 Bacillus cereus
AAB81171      83 SVPSg-SLSFWKERLEKSGLSLEektl--fgekGLIFDDTEDLPLAIM 127 Bacillus subtilis subsp. subtilis str. 168
YP_001635217  83 RVNGaeTLQWWAERLRTEGVPVGevvlr-dgrlTLDFEDPEGQRLMLV 129 Chloroflexus aurantiacus J-10-fl
NP_386596     82 AIPPe-SIGYWMTRALKFNIQATgpsqe-fgepVLRLKDPDGVIVKLV 127 Sinorhizobium meliloti 1021
Q9WXE6        90 NAPVg-TLSWWQEHLIKRAVTVSevrer-fgqkYLSFEHPDCGVGFEI 135 Sphingomonas paucimobilis
NP_773604    117 RVAGd-SLDGWADRLASAGVPYRsevsp-fgerTLCFSDPDGTALSLI 162 Bradyrhizobium japonicum USDA 110
ABP93364      90 NAPVg-TLSWWQEHLIKRAVTVSevrer-fgqkYLSFEHPDCGVGFEI 135 Pseudomonas aeruginosa
AAK26513      86 SVPKh-SLDFWRARFAIKGVPFDrevvsrfgetRQRFQHPCGIEFDLV 132 Pseudomonas putida
NP_814608     82 KIPQn-SLSFWEQRLTENKIPFNkk------ekSLHFSDPDDTHIILT 122 Enterococcus faecalis V583
NP_814418     82 KVPTraSLDFWAERLEQAGICHYgvetf-nqhpILRFEAPDNTQMALV 128 Enterococcus faecalis V583
3OAJ_A        86 VVPKg-AMAFWEKRLEKFNVPYTkier--fgeqYVEFDDPHGLHLEIV 130 Bacillus subtilis subsp. subtilis str. 168
4HUZ_A        88 AIPKg-SLEWWIGHLNAHGIATGepgtr-fgqrYVGFQHPDCGIDFEV 133 Sphingobium chlorophenolicum
O34689        83 RVPGteALHYWKERFEEQQVTHSgiskr-agrdILAFQDHEGQRLVLT 129 Bacillus subtilis subsp. subtilis str. 168

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