2CQK


Conserved Protein Domain Family
LARP_4
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cd08035: LARP_4 
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La RNA-binding domain of La-related protein 4
This domain is found in vertebrate La-related protein 4 (LARP4), also known as c-MPL binding protein. La-type domains often co-occur with RNA-recognition motifs (RRMs). A variety of La-related proteins (LARPs or La ribonucleoproteins), with differing domain architecture, appear to function as RNA-binding proteins in eukaryotic cellular processes.
Links
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Statistics
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PSSM-Id: 153404
Aligned: 4 rows
Threshold Bit Score: 155.204
Threshold Setting Gi: 159163870
Created: 6-Aug-2009
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
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RNA binding
Conserved site includes 10 residues -Click on image for an interactive view with Cn3D
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:by similarity to other members of this family
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1              #  ##    #  ## #                  ###                                
2CQK_A        15 KECLKKQLEFCFSRENLSKDLYLISQMDsDQFIPIWTVANMEEIKKLTTDpDLILEVLRSSPmVQVDEkGEKVRP 89  human
NP_001121273 124 KECLKKQLEFCFSRENLSKDLYLMSQMDsDQFVPIWTIANMEGIKKLTTDmDLILEVLRSTPvVQVDEkGEKVRP 198 African clawed frog
NP_001012718 120 RECLRKQLEFCFSRENLSKDLYLMSQMDsDQFVPIWTIANMEGIKKLTTDmDLILDVLRSSPmVQVDEtGEKVRP 194 chicken
CAG06747      73 RESLKKQLEFCFSRENLSKDLYLISQMDsDHFVPIWAVACMEDIKALTTDmDLILDVLRASPmVQVDEtGEKVRP 147 spotted green puffer...
NP_001121273 124 KECLKKQLEFCFSRENLSKDLYLMSQMDsDQFVPIWTIANMEGIKKLTTDmDLILEVLRSTPvVQVDEkGEKVRP 198 African clawed frog
NP_001012718 120 RECLRKQLEFCFSRENLSKDLYLMSQMDsDQFVPIWTIANMEGIKKLTTDmDLILDVLRSSPmVQVDEtGEKVRP 194 chicken
CAG06747      73 RESLKKQLEFCFSRENLSKDLYLISQMDsDHFVPIWAVACMEDIKALTTDmDLILDVLRASPmVQVDEtGEKVRP 147 spotted green puffer...

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