Conserved Protein Domain Family
LARP_1_2

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cd08034: LARP_1_2 
La RNA-binding domain proteins similar to La-related proteins 1 and 2
This domain is found in proteins similar to vertebrate La-related proteins 1 and 2 (LARP1, LARP2). A variety of La-related proteins (LARPs or La ribonucleoproteins), with differing domain architecture, appear to function as RNA-binding proteins in eukaryotic cellular processes.
Statistics
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PSSM-Id: 153403
View PSSM: cd08034
Aligned: 8 rows
Threshold Bit Score: 141.41
Threshold Setting Gi: 121962894
Created: 16-Apr-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
RNA binding
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:by similarity to other members of this family

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1               #  ##    #  ## #                  ###                                
Q6PKG0        404 KDYIKRQIEYYFSVDNLERDFFLRRKMDadGFLPITLIASFHRVQALTTDiSLIFAALKDSkvVEIVD--EKVRR 476  human
Q9VAW5        460 KEAIKKQVEYYFSVDNLTGDFFLRRKMDpeGYIPVTLIASFHRVLALTTDvAVIVNAIKESdkLELFEg-YKVRT 533  fruit fly
XP_002125534  542 LEYIMWQIEYYFSPDNLERDFFLRRKMDteGFLPLDFIASFQRVQALTTDiDVIYEAIKDSkvIEIVD--NKVRC 614  Ciona intestinalis
XP_781138     682 KDYVKKQIEYYFSVDNLVKDLFLRKKMDteGYLPLSLIASFHRVKALTSDvGVITTALNDSteVELSSdkSKVRC 756  purple urchin
Q21992        324 KEYVRKQIEYYFSEENLQKDFFLRRKMGpeGYLPVALIASFPRVRSLTEDySLILEALKDStkVDMSPdgLQIRA 398  Caenorhabditis ele...
XP_001623976   26 QEYIKRQIEYYFSEANLHKDFFLRKQMDdeGYIPIALIASFYRVQALTHDmNLILETMKDSeiVELNG--TKLRK 98   starlet sea anemone
XP_002112529  326 KDAIRKQIEYYFSQENLLKDFYLRRQMNadGFIPAKTIAVFYRMQKLTKDvNAIVNAVSDSevVEVIG--DQLRC 398  Trichoplax adhaerens
Q659C4        216 KEYIKRQIEYYFSVENLERDFFLRGKMDeqGFLPISLIAGFQRVQALTTNlNLILEALKDSteVEIVD--EKMRK 288  human

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