2CQK


Conserved Protein Domain Family
LARP_4_5_like

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cd08031: LARP_4_5_like 
Click on image for an interactive view with Cn3D
La RNA-binding domain of proteins similar to La-related proteins 4 and 5
This domain is found in proteins similar to La-related proteins 4 and 5 (LARP4, LARP5). A variety of La-related proteins (LARPs or La ribonucleoproteins), with differing domain architecture, appear to function as RNA-binding proteins in eukaryotic cellular processes.
Statistics
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PSSM-Id: 153400
Aligned: 9 rows
Threshold Bit Score: 137.572
Created: 16-Apr-2009
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
RNA binding
Conserved site includes 10 residues -Click on image for an interactive view with Cn3D
Feature 1:RNA binding site [nucleic acid binding site]
Evidence:
  • Comment:by similarity to other members of this family

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1              #  ##    #  ## #                  ###                                
2CQK_A        15 KECLKKQLEFCFSRENLSKDLYLISQMDsdQFIPIWTVANMEEIKKLTTDpDLILEVLRSSpmVQVDEkgEKVRP 89   human
XP_002110870 102 RISLKNELEYYFSRENVASDAYLLSQMDsdQYVPIKTIATFNTIKQLTSDiDLITEILKECstVQLDEdgEKVRP 176  Trichoplax adhaerens
XP_798222     60 RKLLQRQLEYYFSRENLANDRYLQSQMDsdQYVTIRTIANFNAVKKLTHDlQLVIEVLRESpfVQVDGkgEKVRP 134  purple urchin
XP_002124666  24 LDQVKHQLEYYFSRENLTQDPYLVSQMDsqQFVSILTIANFNAVKKLTLDiNLVIEALKASeyVQVDEkcEKVRP 98   Ciona intestinalis
XP_001635007  12 KNLLQHQLEYYFSRENLSRDTYLLSQMDrdNYVPIWTVANFNQVKKLTKDlELVKEALRDSphLQVDSlcEKVRA 86   starlet sea anemone
O44760       139 KQLLKNQLEYYFSRENLSSDRYLKCQMDsdNYVPINVLAGFPKIMRLTTDvDLIVEALKEStnVELDEkfEKVRA 213  Caenorhabditis elegans
AAQ22587     262 KQMLATQLEYYFSRENLANDTYLLSQMDsdQYVPIYTVARFNLVRKLTNDiNLITEVLRESpnVQVDDkgLRVRP 336  fruit fly
Q92615       157 REVLKKTLEFCLSRENLASDMYLISQMDsdQYVPITTVANLDHIKKLSTDvDLIVEVLRSLplVQVDEkgEKVRP 231  human
EEY68029      15 KEAIKRQVEFYFSRANLANDAYLVSQMNsqMYVPVEVIINFSKITQLTDNtALLVEAVQEStvCSLNSskDAIKP 89   Phytophthora infest...

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