Conserved Protein Domain Family
LPLAT_DHAPAT-like

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cd07993: LPLAT_DHAPAT-like 
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like
Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Statistics
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PSSM-Id: 153255
View PSSM: cd07993
Aligned: 39 rows
Threshold Bit Score: 181.232
Threshold Setting Gi: 126648663
Created: 5-Oct-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative
Feature 1:putative acyl-acceptor binding pocket
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                             #  # #                       ####           
O15228        134 FSKVCvn---eeGIQKLQRAIqe-----hPVVLLPSHRSYIDFLMLSFLLYn---yDLPVPVIAAGMDFlgmkmvgELLR 202  human
XP_002186212 1301 FNEVSvdl--fsFAEAIREAEntg--rpiRIVLTPTHRSVFDFILLSFLAFslpelQVDIPFVAAAEDFrqlpiigWLCS 1376 Phaeodactylum...
O53207        248 DPEFDyd---eyQVAAMRAALea-----hPAVLLFSHRSYIDGVVVPVAMQd---nRLPPVHMFGGINLsfg-lmgPLMR 315  Mycobacterium...
AAK45868       71 AYDVLvd---edQITQLRKLDrk-----aTLAFAFSHRSYLDGMLLPEAILa---nRLSPALTFGGANLnff-pmgAWAK 138  Mycobacterium...
ZP_01625503   255 EKALNyn---pqDLERVRSIVrd-----hPSALLWTHKTYIDGFVVPKLLFd---nNFPIPHFFAGANLnip-llgFLGR 322  marine gamma ...
YP_615251     255 APDMEid---aaELAKLRGILre-----hPTCILFTHKTYIDGATPSRLAYe---nDLPMLHSFGGANLdfa-vmgEFFR 322  Sphingopyxis ...
XP_756965     231 HQGIHis---vpQVLELRRVAayaaerkqSILFLPCHKSHIDYLTVSWLMFr---lGIALPHIIAGENLdlp-vlgDVLR 303  Ustilago mayd...
EEH22617      182 HQGIHvsseevlRLRFVAEAAakk---kqSIVFLPCHRSHVDYVSLQIICYr---lGIGLPVVVAGDNLnip-llgSFLQ 254  Paracoccidioi...
XP_844466     604 FDRVSln---asAFERLHAATtqp---rtHVMLLPAHRSYIDFIIMTYLLLv---mGLTLPHVCAGDDFlrmgqitKLMR 674  Trypanosoma b...
YP_629927     470 TSDVTfd---rpSFERAMAQVpp----gtLVVLAPTHRSYFDFLLTSYLCFqhpelGISMPHIAAAEEFgripvvgPILK 542  Myxococcus xa...
Feature 1                                                   ###                                   
O15228        203 MSGAFFMRRTfg-gNKLYWAVFSEYVKTMLrngyaPVEFFLEGTRSRsaktLTPKFGLLNIVMEPFfkr--evfDTYLVP 279  human
XP_002186212 1377 CARAIFIRRGtgqvDPDSNQQIQAIGIHRHgp-vpVMEVFIEGTRSRdgrfAKPKTGVLKCLHQSGi-------DSLIVP 1448 Phaeodactylum...
O53207        316 RSGMIFIRRNig-nDPLYKYVLKEYVGYVVek-rfNLSWSIEGTRSRtgkmLPPKLGLMSYVADAYldg--rsdDILLQG 391  Mycobacterium...
AAK45868      139 RTGAIFIRRQtk-dIPVYRFVLRAYAAQLVqn-hvNLTWSIEGGRTRtgklRPPVFGILRYITDAVdei--dgpEVYLVP 214  Mycobacterium...
ZP_01625503   323 RAGGIFIKRSfa-dNPVYKAALRQYIGYLMek-rfPLTWSFEGTRSRlgklMPPKYGVLKYVIEGChsa--gskDVHIIP 398  marine gamma ...
YP_615251     323 RSGMIFIRRSfq-dQPVYKLVLRHYIAWLLak-rfPLSWAFEGTRSRlgklMPPKYGLMKYVLDAAhat--gtrGVHFIP 398  Sphingopyxis ...
XP_756965     304 KGGAFFIRRSfs-gDQLYPAVIKEYVETLLas-gkNLECFIEGTRSRtgklLPPKLGILKYVVEGLldg--rtdDVWICP 379  Ustilago mayd...
EEH22617      255 RAGAMWIRRTfg-dDSLYHTLVQAYVDTLLkn-gfNFECFVEGGRSRtgklLPPKFGILSFLLDSIasg--rvnDAIICP 330  Paracoccidioi...
XP_844466     675 GSGAFFIRRTfr-dDPLYTALFKEYIHNLVlr-kqMIEFFIEGTRSRtgktQRPMLGVLKFIADTLvnaqeaidDVCILP 752  Trypanosoma b...
YP_629927     543 DSQAFFIKRG----VGREVPELGEELRRLTek-naSLMFFVEGQRSRarlmLPPKRGMLRALQNTKr-------QFVVLP 610  Myxococcus xa...
Feature 1                                                                                     
O15228        280 ISISYDKILEetlyvyellgvpkpke--------sttgllkarkilsenfGSIHVYFGDPV--------SLRSLAA 339  human
XP_002186212 1449 VAISYEAIPEqhymekelvtgaslkmst-----pgalqwlldvfdgknsfGNVLVSAGAPLvmnaaektNFKELVW 1519 Phaeodactylum tri...
O53207        392 VSICFDQLHEiteyaayargaektpeg-------lrwlynfikaqgernfGKIYVRFPEAV--------SMRQYLG 452  Mycobacterium tub...
AAK45868      215 TSIVYDQLHEveamtteaygavkrpe--------dlrflvrlarqqgerlGRAYLDFGEPL--------PLRKRLQ 274  Mycobacterium tub...
ZP_01625503   399 VTVSYDLIRDaeeyareqagvpkape--------slgwlvgyirslarpmGKIYVDFGEPV--------VLPEPPS 458  marine gamma prot...
YP_615251     399 FVTSFDLIRDveeyaaeqtgrnkkpe--------slswfigymkslkepsGRIRLDIGDPV--------VIDTAPG 458  Sphingopyxis alas...
XP_756965     380 VSLQYDSVIEsetyvsellgkpkeaes-------llgllsgsssllqlkmGRIDIRFDTPW--------SLQGFIN 440  Ustilago maydis 521
EEH22617      331 VSTQYDKVIEtdellgqpkqkenl------------vdflnsssvlslklGRVDVRFHEPW--------SLKAFVA 386  Paracoccidioides ...
XP_844466     753 VSLSYDELLEtklyaaeqlglskpre--------svgnlvrassvlsrrhGKIHVHVAEPL--------SLRSFCH 812  Trypanosoma bruce...
YP_629927     611 VAISYDRLPEeaslseelsgkprpkmtltgvlswltkltrgqvqlgrvhlSCGAPLALNPDt-------DVRALSH 679  Myxococcus xanthu...

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