Conserved Protein Domain Family
LPLAT_LPCAT1-like

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cd07991: LPLAT_LPCAT1-like 
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LPCAT1-like
Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lysophosphatidylcholine acyltransferase 1 (LPCAT-1), glycerol-3-phosphate acyltransferase 3 (GPAT3), and similar sequences.
Statistics
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PSSM-Id: 153253
View PSSM: cd07991
Aligned: 52 rows
Threshold Bit Score: 136.582
Threshold Setting Gi: 157777224
Created: 5-Oct-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative
Feature 1:putative acyl-acceptor binding pocket
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                            #  # #               ####                   
Q1LWG4        97 MRAMWfsggfHWVRVKGRpalp----seapILTMAPHSSYFDAIPVtm---tmASIVMKAEskdiPVWGTLIKFi-rPVF 168 zebrafish
XP_638792     92 AKIAMg----IKTTYNGIenlpkkgdknsaRILVCNHLTDFDPYPLfgileenHVMVGSHIrd-vPIVGKLYERf-nTIY 165 Dictyostelium d...
XP_001666678  72 LRTMCsi-lgIVVEKRGErde-------taRVLCANHVSILDHLAIdi---ltPCLLPSVWdi-pSVIRWCFGYvdlGAA 139 Caenorhabditis ...
XP_786775     62 LRTLYtv-lgFIVYPSNLqhrn-----qnvKVIVANHVSVLDHVIIgl---ifPSVVPNVWsl-pPFLNWALGYtnmGAS 131 purple urchin
XP_001696468 174 CCAWVaa-whGVIRYHGPkptp-----gpnRIWVSNHTSMIDYVVLcsy--spFAVIMQLHhgwiAFLQKRILSslgCLW 245 Chlamydomonas r...
ABK24251     136 CSVFVas-wtGVVKYHGPrpsv-----rprQVFVANHTSMIDFIILeqm--taFAVIMQKHpgwvGLLQSTVFKslgCIW 207 Sitka spruce
Q9FF57       124 CSFFVas-wtGVVKYHGPrpsi-----rpkQVYVANHTSMIDFIVLeqm--taFAVIMQKHpgwvGLLQSTILEsvgCIW 195 thale cress
XP_001771507 118 CSVFVas-wtGVVKYHGPrpsr-----rtkQVFVANHTSMIDFVILeqm--tgFSAIMQKHpgwvGFLQTTVLEslgCIW 189 Physcomitrella ...
XP_001707002 190 YHLTLls-igAVVLIHGSipht-----qsgRIYVANHTTIMDAIILssi--kqFAIVGQKYsgllGIIEERILGcldPVW 261 Giardia lamblia...
NP_586146     99 AKSLTla-mnARIKHLGEkkkl-----sepHIYVANHTSFVDLFLLssh-rfpHACVSERHgglfGFLFKSILIrngSIA 171 Encephalitozoon...
Feature 1                                           ###                                          
Q1LWG4       169 VSRSdqdsrrkTVEEIKRRAssng-ewpQIMIFPEGTCT-NRSCLIAFKPGAFIPGVPVQPVVLRYpne------ldTIS 240 zebrafish
XP_638792    166 VDQNn------KAKARIDVLdslsntdfPLLIYPEGGLNnGKTGLMMFNKFVFGLGHSICPIAMRLhnnw----pveTDY 235 Dictyostelium d...
XP_001666678 140 RGRDhl---vnGAKKLLAKEte-----mPLLAFPEGIITsGEKALIKFNTWAFEVAPIVQPVSVRVwrpypwkvavsVLG 211 Caenorhabditis ...
XP_786775    132 QGRQvf---ldAVRKHCQHNt------rPVLAFPEGAMTnGKAGLLKFSTWAFALERDVQPITVTIsrpl----inmKAE 198 purple urchin
XP_001696468 246 FNRTevndravVATRMREHVnnp--dgiPLLIFPEGTCV-NNEYTVMFKRGAFDIGATVCPVAIKYnki------fvDAF 316 Chlamydomonas r...
ABK24251     208 FNRTeakdrhiVSDKIKQHIegh--dnnPLLIFPEGTCV-NNQYTVMFKKGAFELGCTVCPIAIKYnki------fvDAF 278 Sitka spruce
Q9FF57       196 FNRSeakdreiVAKKLRDHVqga--dsnPLLIFPEGTCV-NNNYTVMFKKGAFELDCTVCPIAIKYnki------fvDAF 266 thale cress
XP_001771507 190 FNRTeandrhaVAQKLKNHVndp--danPLLIFPEGTCV-NNEYTVMFKKGAFELDCVVCPIAIKYnki------fvDAF 260 Physcomitrella ...
XP_001707002 262 FNRSdrterteAATKIKNRIydeg-akaPLLLFPEGVLV-NNRFIIMFKKGAFELGAEICPIAIKYnet-----lssHAY 334 Giardia lamblia...
NP_586146    172 FKRSekidrqlVVEKVKEHVwsg---gaPMLIFPEGTCV-NNKFSVLFQKGPFELGVAVCPVAIRFqrr------lfDPY 241 Encephalitozoon...
Feature 1                                                                                  
Q1LWG4       241 WTWQGPgafkiLWLTLCQLHNFVEIEYLPTytpseeekKDPALFASNVRRIMAka-----lGLPIIDYSFEDCQ 309 zebrafish
XP_638792    236 INSSWFk---nFFWWILIPYHHFELTFLPHesi--kqdETDSQFATRVQTIIAnk-----lSLEPTLYNYTQKR 299 Dictyostelium discoid...
XP_001666678 212 ATWWTD-----LFYFFALPFTVISVEYLPKmek--keeESLDEFTARVAETLAanlkisvsKFGISDASEAAKR 278 Caenorhabditis briggs...
XP_786775    199 VLGSSLwq--dLLWFLFVPFTVYRVKVLPVekr--sdfENADEFSRGVQQIMAne-----mRLTPTPFTSADKA 263 purple urchin
XP_001696468 317 WNSRREsfgkhLFRLLTSWALVCDIYFLEPqal--regETPQEFAGRVQAMIAky-----aNLRIVPWDGYLKY 383 Chlamydomonas reinhar...
ABK24251     279 WNSKKLsftmhLVRLMTSWAVVCEVWYLEPqtl--qpgETPIEFAERVRDIISmr-----aGIKKVPWDGYLKY 345 Sitka spruce
Q9FF57       267 WNSRKQsftmhLLQLMTSWAVVCEVWYLEPqti--rpgETGIEFAERVRDMISlr-----aGLKKVPWDGYLKY 333 thale cress
XP_001771507 261 WNSKKQsftmhLVRLMTSWAVVCDVWYLEPqti--kkgETPIEFSERVRDLICtr-----aGIKKVPWDGYLKY 327 Physcomitrella patens...
XP_001707002 335 WSSRDVsfyryLFDLMTNWILIVDVWFLPPtsi--qdgETPEEFAERVKLSIAra-----aRLIPRPWDGYLKY 401 Giardia lamblia ATCC ...
NP_586146    242 WNRRSHgftmhMFYLMTRWRLEAEITWMEPvri--mkdETSTQFSHRVKTIISke-----aGLRNTLWNGFLKS 308 Encephalitozoon cunic...

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