Conserved Protein Domain Family
LPLAT_MGAT-like

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cd07987: LPLAT_MGAT-like 
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: MGAT-like
Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this suubgroup are such LPLATs as 2-acylglycerol O-acyltransferase (MGAT), and similar proteins.
Statistics
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PSSM-Id: 153249
View PSSM: cd07987
Aligned: 44 rows
Threshold Bit Score: 113.537
Threshold Setting Gi: 153004613
Created: 5-Oct-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative
Feature 1:putative acyl-acceptor binding pocket
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                   #  #    #                    ####                    
Q3KPP4        84 FKDYFpirlVKTCDLDPQhNYIMGFHPHGVLv---AGAFGnfctnytgfkeLFPGLTPYLhi---lPFWFRCpf-fREYI 156 African clawed ...
NP_961883     69 VDYWFrm-eIDGWENIPDtPPALLVGVHSGApfvwDAWTVglqw----wrrFGPDRPLHGtah-daLMAIPLf---GRYF 139 Mycobacterium a...
NP_215944     37 LKTYHrs-qVHGLDSFPP-GGALVVANHSGGmfpmDVPVFsvdf----ydkFGYDRPVYTls---hDILFMGl--tGDLF 105 Mycobacterium t...
ABV27240     133 YRHYWrv-qTYGIEHVPP-GRVLLIGNHSGQlp-iDGAMVavam----lleANPPRLCRAm----vERWFTTvpllGTLL 201 Candidatus Chlo...
ZP_01085352   31 YRHYFqv-sTSGWEQIPGeGQMLLVGSHNGGlaspDLPMLmldw----frrIGFERRVYGlahpkvWQVFPRa---AQLA 102 Synechococcus s...
ZP_03890834   69 FSRWFrv-eTHGVENVPDtGGGLVVANHSGTvp-fDAMMAtvalh-ddhpaRRRLRLLGA------DLVFDLpv-iGSLS 138 Geodermatophilu...
YP_001634840 192 YSTWWrv-tATGLEHVPAsGRALLVANHSGVlp-wDGAMIatavf--nehpAQNERIVRSl----hLHWFSTlpiiAPTL 263 Chloroflexus au...
YP_001378938  74 RLGWFsf-eVEGVEHVPRaGRVVFAPNHAGWfp-lDAFFLalav----rraLGAEATPYFaaa-daALAAPVl---GRFL 143 Anaeromyxobacte...
ZP_01908608   54 HRYYFrv-vSAGHENVPLdSAGVVVGNHSGVlp-fDGVMVttdv----frhMDPPRLVRFmv---dFFVYSMpv-vGTLF 123 Plesiocystis pa...
NP_969516     36 LRKYFrl-eIEGVENIPRrGAVILAPNHSGYtg-fDAFLLghv------vqQEAKRIPRVlt---hHFWFLTet-tAIPA 103 Bdellovibrio ba...
Feature 1                                       ###                                              
Q3KPP4       157 MSVGLVsaSKKSVNHVLskedgGNVSIIVTGGAEESldahpgsLTLNILKRKGFIKVALKRGAYLVPVFSFGENELFqqv 236 African clawed ...
NP_961883    140 RSMGVLpaAPDAIATALa---eGRDVALWPGGEVDSlrpwterDRANLAGRTGFVKMAIRAGVPIVPIATVGGADAMpvl 216 Mycobacterium a...
NP_215944    106 RRTGYIraTRENAAKALr---sGGVVVVFPGGDYDAyrptfaeNVIDFNGRKGYVSTAVEAGVPIVPAVSIGGQESQlyl 182 Mycobacterium t...
ABV27240     202 QRSGAIvgDPLNCERLLq---kGEAILVFPEGARGSgkv-wkdRYKLVRFGLGFMRLALATNTPIVPFGVIGGEEQApsf 277 Candidatus Chlo...
ZP_01085352  103 AQTGAIpyYPRGAMAVLe---rGDSLLVFPGGGQDAfrphrlrQSIQFRGRTGFIRLALRHNVPIVPLISWGSHDTLivl 179 Synechococcus s...
ZP_03890834  139 RKLGSTlaCNEDAERLLt---gGELVGVFPEGFKGIgkpfrerYTLQRFGRGGFVTAALRTGAPIIPCAIVGAEETYpmi 215 Geodermatophilu...
YP_001634840 264 AALGQVpgIPENAIRLLe---qDELVCVFPEGLKGVgklfkdrYKLARFGRGGFVQAALRTRSPIIPVAVVGAEEIYpml 340 Chloroflexus au...
YP_001378938 144 SRVGAL--PASSFRRPErlppeIRTVGVFPEGVDGNtkp-fweAYRMRPWKRGFVRVAAALDAPIVPVAILGGEESLpva 220 Anaeromyxobacte...
ZP_01908608  124 RSLGQIpgTRRNFDGLIe---eGHLVGIFPEGADALgkp-medRYQLFPFSHGHAELAARHGVPVIPFGVVGAEEQQavi 199 Plesiocystis pa...
NP_969516    104 NKMGFTeaTYENGINALk---kGNAIVLFPEGEQGNfkp-tteRYQLQEFKRGFVRMALEAQCPIVPVVILGAEETHinl 179 Bdellovibrio ba...
Feature 1                                                                                        
Q3KPP4       237 snpkgsll------------------rcvqerlqriMGLAMPLfhargifqy--sfglmpyrmPIHTVVGrpipvke--- 293 African clawed ...
NP_961883    217 irgdrlskalrldrllrlkvfplaislpwgiapaalPQLPLPAki----------------rtRFMPPVEld-------- 272 Mycobacterium a...
NP_215944    183 sr-----------------------------gtwlaRRLGLKRllr---------------sdILPISFGfpfgfsaaip 218 Mycobacterium t...
ABV27240     278 vd-----------------------------ckplaRLLGMPYfp----------------itPTFPWLGvlgmipfptk 312 Candidatus Chlo...
ZP_01085352  180 edcye------------------------pmqrwheRGLPWLFgidpevf-------plylglPWGLAVGplpnlplpak 228 Synechococcus s...
ZP_03890834  216 gn-----------------------------vktlaRLLGLPYfpvtptfpalgplgllplpsKWLIAFGepiet----- 261 Geodermatophilu...
YP_001634840 341 an-----------------------------aegiaKLLGFPYfp----------------ltPFFPWFGllgviplptr 375 Chloroflexus au...
YP_001378938 221 wtvrflep------------------llgssvglpvFALPLPA--------------------RWKVVFH---------- 252 Anaeromyxobacte...
ZP_01908608  200 sn-----------------------------meplaRAFGLPFvp----------------ltRTFPLFGplgllpkpvr 234 Plesiocystis pa...
NP_969516    180 kklkftkf------------------lkgsviplplNVIPLPAkwri------------rflePITLPYKp--------- 220 Bdellovibrio ba...
Feature 1                                                                      
Q3KPP4       294 --------------------tshptqeEIESLHQQYLg-------------ALQELFEEHKK 322 African clawed frog
NP_961883    273 --------------------------nDPARVQDDEYver--------kyrEVQDSIQQGMD 300 Mycobacterium avium subsp. paratu...
NP_215944    219 pnlplpakivmqvldpinltkqfgedpDVDAVDEHVRsvm---------qqALNDLAAKRRF 271 Mycobacterium tuberculosis H37Rv
ABV27240     313 yriyf-------geplifrgnpddrdeVIQRKVDRVKr-------------EIRRLIDRGLE 354 Candidatus Chloracidobacterium th...
ZP_01085352  229 ihtrvcr----piqfersghaasrdrsYVQSCYTRVVaem---------qeQLDELAGTSRS 277 Synechococcus sp. WH 5701
ZP_03890834  262 ----------------------asygpAAAEDPMLVFnl----------tdQVRETIQQSLY 291 Geodermatophilus obscurus DSM 43160
YP_001634840 376 wsi-----------tfcppiatdeydaDAADDPITVLal----------seQVRETIQEVIN 416 Chloroflexus aurantiacus J-10-fl
YP_001378938 253 ---------------------------PPVTVGARGRaalvdseyssavarAVQGTVQDTLD 287 Anaeromyxobacter sp. Fw109-5
ZP_01908608  235 y----------------yihygppltiDPAALRSVEVrarev----ervreAVNAQIELGLE 276 Plesiocystis pacifica SIR-1
NP_969516    221 ---------------------------SAVDDADLVHeiaqdi--qermqtAVEEEIQKRGN 253 Bdellovibrio bacteriovorus HD100

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