Conserved Protein Domain Family
LPLAT_DUF374-like

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cd07983: LPLAT_DUF374-like 
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374
Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are the uncharacterized DUF374 phospholipid/glycerol acyltransferases and similar proteins.
Statistics
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PSSM-Id: 153245
View PSSM: cd07983
Aligned: 61 rows
Threshold Bit Score: 170.857
Threshold Setting Gi: 19704604
Created: 5-Oct-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative
Feature 1:putative acyl-acceptor binding pocket
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                          #  # #               ####                    
ZP_01018483  24 IRLVEglVRWDRVGhehyqsl--iasgapFICAFWHARLMMMPIIqrqqgrpLAVLVSEHRDGemIAQVMTHFSIDTRRG 101 Parvularcula ber...
13476831     23 VRLVRltSPLVAGSarfsgga--yaefepGIIALWHGQHLLTPAYypk-rkpLVAMVSRSADAelNALMLEKFGIEAVRG 99  Mesorhizobium lo...
NP_697454    18 LRFVWwsSRNTAGRnetnpl----aqagpCIVAMWHGQMFLAAFArpp-ekkFVAAVSKSRDGelVAQMLGKLGIRAIRG 92  Brucella suis 1330
NP_945418    24 SKIYFkfVMWTGRYdrqav-----pipepYILAMWHGRLIMAPMLqtk-skpLVALISGHRDGkiISRVGAAFGIQTAVG 97  Rhodopseudomonas...
ZP_00953007  37 MSLVKatTRWEVRGlehaqsl--wssgdgVICGVWHGRILMTIAAwpknvqpPAILISRSREGdvVTKVAAHHKVEVIRG 114 Oceanicaulis ale...
ZP_01048141  26 LWLVWrtNRFSYDPeevydi---vepqmpVILAFWHGQHFMTPFIrra-hhrGKVLISRHRDGefNALAAERLGIETIRG 101 Nitrobacter sp. ...
ZP_01089911  20 IRHWLdtLDLRVAYhdpqldpahpsndrpRIYIFWHEYISFPLYLrpy--cnIAMLLSKHRDAewLAHTATMMGFDTVRG 97  Blastopirellula ...
CAM77836     30 IRLIWltGRWRVENghipasy--wdrgqpFILSFWHGRLLMMMKSwrr-glpISMLTSEHRDGqlIARTAAPFGIGTITG 106 Magnetospirillum...
ZP_01853233  20 IRMIFktTRLEFVGdsldrcpfadtgserYLYSVWHDSVIPPLFCnve--hnSVALISQHRDAdtIEAMLKAARMGAIRG 97  Planctomyces mar...
ZP_02191896  23 VRMINatTRWEHVAdpaaaal--lagdqpVIGAFWHNRLMLISAVwpk-gkpIAMVQSEHGDSriLGIAVSEYITRPIWG 99  alpha proteobact...
Feature 1                                           ###                                         
ZP_01018483 102 SGADPrkpeknkggasALKALTRILkegkNAGITPDGPRGPr-RQAQGGAAQLSrlsgaPIIPIAISVrwg-lrLNSWDR 179 Parvularcula ber...
13476831    100 SGGRDnarhldkggakALIALKKSLtagkNVAMIADIPHGTp-RDAGLGIVLLArlsgrPLLPVAIATsrrkvlEKSWDK 178 Mesorhizobium lo...
NP_697454    93 SGAGQrkgnr-qggaaALRQMLYALrngeSIVMAAETNKKV--FRCGEGVIALArlsgcPIYPASARTsft-rtLNSWDR 168 Brucella suis 1330
NP_945418    98 SSSKGgm--------rAAREMMRLGksghSLFVTPDGPRGPrmRINSEGVLDMArltglPILPVSVSLsrh-klLRSWDR 168 Rhodopseudomonas...
ZP_00953007 115 SSRNKkktkq-kgglsAFREMVRWVegggCMALTPDGPRGPr-MRAGLGAVKLAratgaPLLGLGWSTsna-liFKSWDR 191 Oceanicaulis ale...
ZP_01048141 102 SGDHGsafsr-kggvgAFKEMVRALeegyNMALTADVPKRS--RIAGLGIIMLAresgrTIMPFAMATsrf-irLNNWDR 177 Nitrobacter sp. ...
ZP_01089911  98 SSQRGga--------sALLELLEKSkn-mHLAITPDGPRGPr-RRLAPGAIFLAsrlglPLIPMGFGFdrp-krAKTWDQ 166 Blastopirellula ...
CAM77836    107 SSTRGga--------gGLRALLKALkagaYVGITPDGPKGPr-MRATDGIITLAklsgvPIIPLTYSAspr-wlLKSWDR 176 Magnetospirillum...
ZP_01853233  98 STTRGga--------sAMKKLMTSAeg-kHVVITPDGPRGPh-HQMKPGIVFLAshsgrSIIPNAFAAsrswkfQGSWTS 167 Planctomyces mar...
ZP_02191896 100 SSRRNpm--------aALKGMLRALqeglSVGITPDGPRGPr-MRCRPGLIHAAkrsgvPIVPGAWSVsrr-svARSWDR 169 alpha proteobact...
Feature 1                                                          
ZP_01018483 180 FLIPLPvpFGKGAIVFGPPltiprtg---------lsidaasRRITDALNQ 221 Parvularcula bermudensis HTCC2503
13476831    179 TTINLP--FGRSAVTIGAPifvaadad-------daemerkrQEITTALNA 220 Mesorhizobium loti MAFF303099
NP_697454   169 AELPMP--FGRRSVVIGEPifvprdas-------deeleqyrLQVEQVINQ 210 Brucella suis 1330
NP_945418   169 LMLPGL--FAKVAIRFGEPitveags----------ptaemaERLQAALTA 207 Rhodopseudomonas palustris CGA009
ZP_00953007 192 FVLPLP--FGKGVIVWAEPvridadad-------kaaletarATLEARLIA 233 Oceanicaulis alexandrii HTCC2633
ZP_01048141 178 TTINLP--FGRGALVGGEPisvpadad-------armmemlrARLEATLND 219 Nitrobacter sp. Nb-311A
ZP_01089911 167 FAIPRL--FSRGRGLMGPGitippnqt-------rdqleqhrQRVERILNQ 208 Blastopirellula marina DSM 3645
CAM77836    177 FLVPGL--FGQGVFIWGEPihvardad-------eaqmehwrLHLENALNG 218 Magnetospirillum gryphiswaldense MSR-1
ZP_01853233 168 IWIPKP--FATVYYLVGNPihvpedisreemreytdlvqekmEELEQELEQ 216 Planctomyces maris DSM 8797
ZP_02191896 170 FIIAWP--FGRGVIVLGAPirvpadad-------etgleacrRQVEDALNA 211 alpha proteobacterium BAL199

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