Conserved Protein Domain Family
bacterial_phosphagen_kinase

?
cd07930: bacterial_phosphagen_kinase 
Phosphagen (guanidino) kinases found in bacteria.
Phosphagen (guanidino) kinases are enzymes that transphosphorylate a high energy phosphoguanidino compound, such as phosphocreatine (PCr) or phosphoarginine, which is used as an energy-storage and -transport metabolite, to ADP, thereby creating ATP. This subfamily is specific to bacteria and lacks an N-terminal domain, which otherwise forms part of the substrate binding site. Most of the catalytic residues are found in the larger C-terminal domain, however, which appears conserved in these bacterial proteins. Their functions have not been characterized.
Statistics
?
PSSM-Id: 153077
View PSSM: cd07930
Aligned: 63 rows
Threshold Bit Score: 233.941
Threshold Setting Gi: 15618611
Created: 28-Aug-2009
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
Feature 1:ADP binding site [chemical binding site]
Evidence:
  • Comment:by similarity to other members of this superfamily

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1             # # #                                                            #         
P37570        22 SDIVLSSRIRLARNFEHIRFPtrySNEEASSIIQQFEDQFSeqeipgiGKFVLIRMNDaqpLEKRVLVEKHLISPNLT-E 100 Bacillus subtilis
B2TIE4        12 EDIVINSNISLSRNLKEKPFSnklNEIEARENVGFIYQIVKse---lkDESCIYQLWNedkELINSYLDKQLISKELIkN 88  Clostridium bot...
BAB82148      10 NSIVIASKVKILRNIKGIKFTkllNEEEFNDLLSMVLGRLKeid--ilDKCYVVKLKDgeeKIIDYYKENFGLIKYFE-N 86  Clostridium per...
NP_220194     20 ETPRPICTLSLSRNLSVSKFVpclSKENKRDVLETIAKQFSai---egEEFFVLPLKDlpiWQRECLLEHYLFPYHLGsY 96  Chlamydia trach...
NP_972640     16 TDVVLYSRCDIARNISGFLFPnkiNLSDSADVVSLVFSFFCslg--dsSYFKKLKLRAmdpLSIKLLEERGIILPDMP-E 92  Treponema denti...
YP_001307268  11 FGAVLSSKVLLARNFSNLPFPnklNYIKGRENGKEVYNVLKnel--dnEEITLYEIWNtkeEFSKQYLERDLISKELLkN 88  Clostridium bei...
ZP_02951220   11 NDIVISTKIQLSRNIEKIPFPeklTVADGRKNVETIYNSIKdsf--esDDLELYEIWErdkRLFNEYLDKNLISDTLLkN 88  Clostridium but...
YP_002251190  20 REVVVSTRIRIARNLEDFVFPsqlLESQRKRILNKVEWVYKnet--rfSEYDFLKLEKlpnIVLDALVEKHLISSDHLeN 97  Dictyoglomus th...
YP_002930150  12 SDVVISSRVRLARNINGYNFSykmSDTDAKKLVKNVTDQLKtvs--piSGYNSYNFDYldaYQKMGMRERHVISPYLE-K 88  Eubacterium eli...
ZP_03462988   16 SDVVISSRVRLARNIRDYNFSlklDGKSASDMIDKTMTELSgcm--efADYTGYNFKDlneYQKHAMEERHTISRFLM-E 92  Bacteroides pec...
Feature 1                        #       #                                                  # ###
P37570       101 SPFGGCLLSENeEVSVMLNEEDHIRIQCLFPGfQLLEAMKAANQVDDWIEEKVdYAFNEQRGYLTSCPTNVGTGLRASVM 180 Bacillus subtilis
B2TIE4        89 KDKTAFVLNSEeTLSIMINEDDHLKLRCITAGfDLETAFDNITKLDDKIEKRVhYAFDENLGYLTTSPTNLGTGMRASVN 168 Clostridium bot...
BAB82148      87 KDNLIFIMNKNgEFNILLNEEEHIGIECTNSGlSLREVYSKVDKLDDLIEEKIhYSFDSELGYLTSNIKNLGTALRTKVF 166 Clostridium per...
NP_220194     97 LEGEALIVNQAgTLLAGINLRDHLVIHGVDFVwQPEVLLQKLIDLDIRLQQSLsFAFSSDFGFLTADPLRCGTALIARAF 176 Chlamydia trach...
NP_972640     93 KIEKAVLVHENgSLYIGLNLEDHINITSFAAGmDPEEVYARASFVELKMREKIkFAEDRDLGFLTSNLMKIGTGLKFSVL 172 Treponema denti...
YP_001307268  89 SDKGSFILNKEeDLSIMINEKDHINLQCVSDGlKLEEIFERATVIDDKIEENFdYAFDETLGYLTASPENIGTGMKASVV 168 Clostridium bei...
ZP_02951220   89 SDKASFILNRDeTMSIMINEEDHIKIQCITSGlNLEEVLQNVVKIDEEIEKNVkYAFDEEFGYLTSRIENVGAAMKVQVL 168 Clostridium but...
YP_002251190  98 IRGAGLLVDKSgKLSVMINEEDHFRLQVLSSGlELKESWKKLLSLEEIFSDYFkFAFDDKFGYLTSCITNLGCGVRISFV 177 Dictyoglomus th...
YP_002930150  89 QDYAAGFVAPDeDVSIMINEEDHIRIQAFAAGmNMQKAYTLADKMDDVIGDVLdYSYDQKFGYLTTLPSNAGTGMRASYM 168 Eubacterium eli...
ZP_03462988   93 QKYAAGLVSPEeDVSVMINEEDHIRIQSFVSGrDMKSAYQKASSADDIIGRHVpYAYHEKYGYLTTCLSSVGTGMRASYM 172 Bacteroides pec...
Feature 1                                    # # ##          #                                
P37570       181 MHLPALVLtrqINRIIPAINQL--GLVVRGIYGEGSEAVGn-IFQISNQITLGksEQDIVEDLNSVAAQLIEQERSA 254 Bacillus subtilis
B2TIE4       169 IHLPALNFndeISNFSKGLTQI--GMDMKGLYEEGNKAYGn-MYKISNQVTLGltEEEIIDNLKGAVLNVISEEKKF 242 Clostridium botuli...
BAB82148     167 IHLPLLSSnnlIRIIKNALKEE--GITLKSIYNSGNKDVGn-IYEVSNIKTLGmsEKDILDSLISITNKLILREKNQ 240 Clostridium perfri...
NP_220194    177 VHVPALKY---GDALSELLVPYqrEFASSSLLPLSQESLGd-ILCLSNICSLGlsEEQILSSLRLVVSKILSAEREA 249 Chlamydia trachoma...
NP_972640    173 CSFPGILYsncLGSVLELTKQN--NLNVAGYYSPNSKSSIgaLFLISNAVSAGdnEEIQTEDFISCVNSIIEIEREK 247 Treponema denticol...
YP_001307268 169 LHLPALSMseeINNISKRLGKL--GIAIKGVHLDGTKVFGn-LYRISNKVSLGltEENIINKLKEAVWSIIIEENKF 242 Clostridium beijer...
ZP_02951220  169 IHLPAITMseeVENLSKRLNNK--GLEIKGLYLEGSDSLGn-IYIISNKASLGvtEENIICTMKEEVLKLIADEYKF 242 Clostridium butyri...
YP_002251190 178 VHLPALTYsgkIKDFLKKLRSN--KILIRGIYGERSKPIAg-FYQITSRSSLGiaEEELIEKMEKVARKIIDEEVIV 251 Dictyoglomus therm...
YP_002930150 169 LHLPALAGndkISGLIPEVGRF--GLVLKAMEGDNNRALGd-IYQLTNLVTLGksEKDIIDNLDNIAEQIIAQERNY 242 Eubacterium eligen...
ZP_03462988  173 LHLPALSGtgqLAGIIGELGRF--GLKMTSVFGEGSSSPGd-IYRISNQTTLGltEQELIDNLDNIAGQIIEQERLG 246 Bacteroides pectin...

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap