Conserved Protein Domain Family
STKc_TEY_MAPK

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cd07858: STKc_TEY_MAPK 
Catalytic domain of the Serine/Threonine Kinases, Plant TEY Mitogen-Activated Protein Kinases
STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. Plant MAPKs are typed based on the conserved phosphorylation motif present in the activation loop, TEY and TDY. This subfamily represents the TEY subtype of plant MAPKs and is further subdivided into three groups (A, B, and C). Group A is represented by AtMPK3, AtMPK6, Nicotiana tabacum BTF4 (NtNTF4), among others. They are mostly involved in environmental and hormonal responses. AtMPK3 and AtMPK6 are also key regulators for stomatal development and patterning. Group B is represented by AtMPK4, AtMPK13, and NtNTF6, among others. They may be involved in both cell division and environmental stress response. AtMPK4 also participates in regulating innate immunity. Group C is represented by AtMPK1, AtMPK2, NtNTF3, Oryza sativa MAPK4 (OsMAPK4), among others. They may also be involved in stress responses. AtMPK1 and AtMPK2 are activated following mechanical injury and in the presence of stress chemicals such as jasmonic acid, hydrogen peroxide and abscisic acid. OsMAPK4 is also called OsMSRMK3 for Multiple Stress-Responsive MAPK3. In plants, MAPKs are associated with physiological, developmental, hormonal, and stress responses. Some plants show numerous gene duplications of MAPKs; Arabidopsis thaliana harbors at least 20 MAPKs, named AtMPK1-20. The TEY MAPK subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.
Statistics
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PSSM-Id: 143363
View PSSM: cd07858
Aligned: 16 rows
Threshold Bit Score: 659.447
Threshold Setting Gi: 66807963
Created: 24-Sep-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                     #### ## #            # #                #             #            
NP_172492     26 FEIDTKYMPIK-PIGRGAYGVVCSSVNSDTnEKVAIKKIHNVYENRIDALRTLRELKLLRHLRHENVIALKDVMMPihkm 104 thale cress
Q5Z859        26 FEIDTKYVPIK-PIGRGAYGIVCSSINRATnEKVAIKKINNVFDNRVDALRTLRELKLLRHLRHENVIALKDIMMPvhrr 104 Oryza sativa Ja...
Q40517        26 FEIDTKYVPIK-PIGRGAYGIVCSSVNRETnEKVAIKKINNAFENRIDALRTLRELKLLRHLRHENVIALKDVMMPihrr 104 common tobacco
NP_564746     26 FEIDTKYVPIK-PIGRGAYGVVCSSVNRESnERVAIKKIHNVFENRIDALRTLRELKLLRHLRHENVVALKDVMMAnhkr 104 thale cress
BAB18271      52 FECPAKYLPIK-PIGKGAYGVVCSAKNLDNqEKVAIKKIANAFDNVIDAKRTLREIKLLRHLQHENIVQIKDIIPPtnrd 130 Chlamydomonas r...
XP_637704    143 FTVPRRYSIVK-CIGHGAYGVVCSAKDNLTgEKVAIKKISKAFDNLKDTKRTLREIHLLRHFKHENLISIKDILKPnske 221 Dictyostelium d...
CAL55559      95 FEVDAKYAPIK-PVGKGAYGVVCSAREVETnRKVAIKKIVNVFENVVDAKRTLREIKLLRHLRHENVIDIIDCVRPeamd 173 Ostreococcus tauri
XP_001776547  26 FEIDTKYAPIK-PIGKGAYGVVCSAKNNETgDRVAIKKITNAFENTTDARRTLREIRLLRHLFHENIIAVKDIMKPvgrq 104 Physcomitrella ...
Q39026        56 FEVTAKYKPPImPIGKGAYGIVCSAMNSETnESVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPplrn 135 thale cress
Q40532        53 FEVTAKYKPPImPIGKGAYGIVCSALNSETnEHVAIKKIANAFDNKIDAKRTLREIKLLRHMDHENIVAIRDIIPPpqre 132 common tobacco
Feature 1                ####  # ##                                   # # ## #         ##  #     
NP_172492    105 sFKDVYLVYELMDTDLHQIIKSSQVlSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARASN 184 thale cress
Q5Z859       105 sFKDVYLVYELMDTDLHQIIKSSQPlSNDHCQYFLFQLLRGLKYLHSAGILHRDLKPGNLLVNANCDLKICDFGLARTNN 184 Oryza sativa Ja...
Q40517       105 sFKDVYLVYELMDTDLHQIIKSSQTlSNDHCQYFLFQLLRGLKYLHSANILHRDLKPGNLLINANCDLKICDFGLARTSS 184 common tobacco
NP_564746    105 sFKDVYLVYELMDTDLHQIIKSSQVlSNDHCQYFLFQLLRGLKYIHSANILHRDLKPGNLLVNANCDLKICDFGLARTSN 184 thale cress
BAB18271     131 aFKDLYVVYELMDTDLHQIIRSPQAlSNDHSQYFLYQLLRGLKYIHSANILHRDLKPSNLLVNANCDLKICDFGLARTST 210 Chlamydomonas r...
XP_637704    222 qFEDVYIVSELMDTDLHQIITSPQPlSDDHCQYFVYQMLRGLKHIHSANVLHRDLKPSNLLINEDCLLKICDLGLARVED 301 Dictyostelium d...
CAL55559     174 aFEDVYLMYDLMDTDLYQIIRSSQSlTDEHCQYFLYQILRGLKYIHSADVLHRDLKPGNLLLNANCDLKICDFGLARTAL 253 Ostreococcus tauri
XP_001776547 105 tFNDVYIVYELMDTDLHQIIRSSQTlTDDHCQYFIYQLLRGLKYVHSANVLHRDLKPSNLLLNASCDLKICDFGLARTGS 184 Physcomitrella ...
Q39026       136 aFNDVYIAYELMDTDLHQIIRSNQAlSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS 215 thale cress
Q40532       133 aFNDVYIAYELMDTDLHQIIRSNQGlSEEHCQYFLYQILRGLKYIHSANVLHRDLKPSNLLLNANCDLKICDFGLARVTS 212 common tobacco
Feature 1                 # #### #                                      #                        
NP_172492    185 TKg---QFMTEYVVTRWYRAPELLLCCDN-YGTSIDVWSVGCIFAELLGRKPIFQGTECLNQLKLIVNILGSQREEDl-e 259 thale cress
Q5Z859       185 TK----GQFMTEYVVTRWYRAPELLLCCDnYGTSIDVWSVGCIFAELLGRKPIFPGTECLNQLKLIVNVLGTMSEADi-e 259 Oryza sativa Ja...
Q40517       185 GKd---QFMTEYVVTRWYRAPELLLCCDN-YGTSIDVWSVGCIFAELLGRKPVFPGTECLNQLKLIINILGSQREEDi-e 259 common tobacco
NP_564746    185 TKg---QFMTEYVVTRWYRAPELLLCCDN-YGTSIDVWSVGCIFAELLGRKPVFPGTECLNQIKLIINILGSQREEDl-e 259 thale cress
BAB18271     211 SNe--kEFMTEYVVTRWYRAPELLLSCSG-YTTAIDVWSVGCIFAELLGRKPLFPGKDYVHQLSLITKVIGSPSEEEl-g 286 Chlamydomonas r...
XP_637704    302 ATh--qGFMTEYVATRWYRAPEVILSWNK-YTKAIDIWSVGCIFAELLGRKPLFQGKDYIHQITLIIETIGSPSEEDi-c 377 Dictyostelium d...
CAL55559     254 VDaeasEFMTEYVVTRWYRAPELLLSCAE-YTSAIDVWSVGCIFAELLGRKTLFPGKDYVHQLNLIMRVIGTPRDDSeld 332 Ostreococcus tauri
XP_001776547 185 DKg---QFMTEYVVTRWYRAPELLLSCDE-YTSAIDMWSVGCIFAELLGRKPLFPGKDYIHQLKLIISIIGSPDETDl-h 259 Physcomitrella ...
Q39026       216 ES----DFMTEYVVTRWYRAPELLLNSSD-YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEEEl-- 288 thale cress
Q40532       213 ET----DFMTEYVVTRWYRAPELLLNSSD-YTAAIDVWSVGCIFMELMDRKPLFPGRDHVHQLRLLMELIGTPSEAEm-- 285 common tobacco
Feature 1                                                                                        
NP_172492    260 FIDNPKAKRYIRSLPYSPGMSLSRLYPGaHVLAIDLLQKMLVFDPSKRISVSEALQHPYMAPLYDPNANPpaqVPIDLDV 339 thale cress
Q5Z859       260 FIDNPKARKYIKTLPYTPGIPLTSMYPQaHPLAIDLLQKMLVFDPSKRISVTEALEHPYMSPLYDPSANPpaqVPIDLDI 339 Oryza sativa Ja...
Q40517       260 FIDNPKARKYIKSLPYSPGTPFSRLYPHaHPLAIDLLQRMLVFDPSKRISVIEALQHPYMSPLYDPNTDPpaqVPINLDI 339 common tobacco
NP_564746    260 FIDNPKAKRYIESLPYSPGISFSRLYPGaNVLAIDLLQKMLVLDPSKRISVTEALQHPYMAPLYDPSANPpaqVPIDLDV 339 thale cress
BAB18271     287 FITSEKAKRYIRSLPRSERVDFGQLWPHvTKTALDLIDKMLVFDPTKRITVEQALEHPYLASLHDVSDEPvcpTPFTFDF 366 Chlamydomonas r...
XP_637704    378 NIANEQARQFIRNMGNQPKVNFANMFPKaNPDAIDLLERMLYFDPSKRLTVEEALAHPYFQSLHDPSDEPiclHKFSLNF 457 Dictyostelium d...
CAL55559     333 FINNEKARRYIKSLPVTARCNFRKLFPNaSPKAVDLVDKMLVLDPARRITVEDALAHPYLESLHDEVDEPcaeTPFTFNF 412 Ostreococcus tauri
XP_001776547 260 FIQSQKARSYIRSLPFTPRVSLARLYPRaNPLAIQLIDKMLVFDPRKRITVHEALEHPYLSMLHDATVEPsapAPFEFDF 339 Physcomitrella ...
Q39026       289 EFLNENAKRYIRQLPPYPRQSITDKFPTvHPLAIDLIEKMLTFDPRRRITVLDALAHPYLNSLHDISDEPectIPFNFDF 368 thale cress
Q40532       286 EFLNENAKRYIRQLPLYRRQSFVEKFPHvNPAAIDLVEKMLTFDPRRRITVEDALAHPYLTSLHDISDEPvcmTPFNFDF 365 common tobacco
Feature 1                                 
NP_172492    340 DEd---lREEMIREMMWNEMLHYHP 361 thale cress
Q5Z859       340 DEn---lGVDMIREMMWQEMLHYHP 361 Oryza sativa Japonica Group
Q40517       340 DEd---lGEETIREMMWSEILEYHP 361 common tobacco
NP_564746    340 DEde-dlGAEMIRELMWKEMIHYHP 363 thale cress
BAB18271     367 DSeh--lTPDVVREVILQDMAELHT 389 Chlamydomonas reinhardtii
XP_637704    458 EAwd--lNRDLLKELIYNEMLAYHP 480 Dictyostelium discoideum AX4
CAL55559     413 EEdgrylTGTDIRELIYTELCSLSD 437 Ostreococcus tauri
XP_001776547 340 EDed--lKEDALRERVWNEMLFYHP 362 Physcomitrella patens subsp. patens
Q39026       369 ENha--lSEEQMKELIYREALAFNP 391 thale cress
Q40532       366 EQha--lTEEQMKELIYREGLAFNP 388 common tobacco

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