Conserved Protein Domain Family
BAR_SH3P_plant

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cd07607: BAR_SH3P_plant 
The Bin/Amphiphysin/Rvs (BAR) domain of the plant SH3 domain-containing proteins
BAR domains are dimerization, lipid binding and curvature sensing modules found in many different proteins with diverse functions including organelle biogenesis, membrane trafficking or remodeling, and cell division and migration. This group is composed of proteins with similarity to Arabidopsis thaliana SH3 domain-containing proteins 1 (SH3P1) and 2 (SH3P2). SH3P1 is involved in the trafficking of clathrin-coated vesicles. It is localized at the plasma membrane and is associated with vesicles of the trans-Golgi network. Yeast complementation studies reveal that SH3P1 has similar functions to the Saccharomyces cerevisiae Rvs167p, which is involved in endocytosis and actin cytoskeletal arrangement. Members of this group contain an N-terminal BAR domain and a C-terminal SH3 domain. BAR domains form dimers that bind to membranes, induce membrane bending and curvature, and may also be involved in protein-protein interactions.
Statistics
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PSSM-Id: 153291
View PSSM: cd07607
Aligned: 7 rows
Threshold Bit Score: 342.537
Threshold Setting Gi: 168046811
Created: 13-May-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
dimer interface
Feature 1:dimer interface [polypeptide binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                #  ##   # ##  ## ##         ## ##  ## ##  #               #  ##         
ABR18100      47 QHLERLYISTRAAKHFQRDIVRGVEGHISagskqmeYAIKLADDCCKYANDgpnsnsa-lsrasfYFGSSHNAMEKERED 125 Sitka spruce
XP_001752175  33 QELERLYTSTRAAKHFQKDVVKGVEGLVStgkrqleIEIRFGQDCTKYGLEgasvtes-lsratqHYGSARGRMEKEREN 111 Physcomitrella ...
XP_001774026  21 LELERLHASTRAAKHFQRDVVKAVEGIIStgakqleVTTKLAEDCRKYGSEapsgitealsratlQYSSARNRMDTERDN 100 Physcomitrella ...
NP_174429     45 QKLQDLYSSTKAAKRLQRNIVRGLEGFIAtgtkvveIGLKFAEDFKKYGDEnpdantp-lsrvahHFGTSYKSVEGERET 123 thale cress
XP_001775866  46 QQLEKLYASTRAAKHFQRELVRGVEGIVStgskqleVANKLADECKKYGTEgvgvgga-lskaslQYGTAKIQMEKERDS 124 Physcomitrella ...
AAP06881      46 QNLQRLYNSTRAAKHFQRSIVRGVEGFIAvstkqmeIVKKLAEDCCRYGNDnqnfgfi-larasvEFGNSHSQMEKEREN 124 Japanese rice
NP_567969     45 QKLEKLYISTRAAKHYQRDIVRGVEGYIVtgskqveIGTKLSEDSRKYGSEntctngnvltraalNYGRARAQMEKERGN 124 thale cress
Feature 1                                                                                        
ABR18100     126 LHRIFGVQVTEPLRAMVvGAPLEDARHLAQRYDRIRQEVEVQTAEvarrqlkskeagatadnafKLQAAESKLADLISTM 205 Sitka spruce
XP_001752175 112 FHRVISLQVAEPLKAMVqGSPLEDARHLKQKYDRLRESVDSHASEvqkrktkda--ngnpehaaKLRAAEQKLDEIISAM 189 Physcomitrella ...
XP_001774026 101 MHRALAAQVSEPLKTMVaGSPLVDARHLKQKYDRLHESADAQAAEvnrrrskeg--ggnsdnaaKLQSAEQKLDQITAAM 178 Physcomitrella ...
NP_174429    124 LLGVLSEQVCEPIRTMIySAPLEDARHLVNHYDRLRQEVEAQATDvlrrrsklkesdiseeayiKLKNSESRLAELKSSM 203 thale cress
XP_001775866 125 MHRVLSTQVADPLRAMVnGAPLEDARQLTQRYDRLRQEAETQASEvskrrtkd---agglenvvKLQVAETKMQELSSSM 201 Physcomitrella ...
AAP06881     125 LLKFLGEQVFEPLREMImSAPLEDARLLTYRYQRIRQDMESQIADvmrkqlkskessgnadnsvKLQHAESKLSELRTTL 204 Japanese rice
NP_567969    125 MLKALGTQVAEPLRAMVlGAPLEDARHLAQRYDRMRQEAEAQATEvarrqakaresqgnpdilmKLESAEAKLHDLKSNM 204 thale cress
Feature 1                   #  ## #    #  ## ##  ##  ## ##  ## ##  
ABR18100     206 SALGKEAASAMMAVEAQQQrltLQRLLAMVEAERTYHEHLAEILDKLHAQ 255 Sitka spruce
XP_001752175 190 NTMGKNATSAMSVVETQQQqttLHKMLSMVEAERAYFQRVTSILDTLHHE 239 Physcomitrella patens subsp. patens
XP_001774026 179 NTMGTSAIFAMNKVESQQQtvtLHRMLAMVEAERAYFQTVCSVLDQLHAD 228 Physcomitrella patens subsp. patens
NP_174429    204 KTLGKEATKAMLEVDDQQQnvtSQRLRALVEAERSYHRNALDILDKLHSE 253 thale cress
XP_001775866 202 AVLGKEAASAMTAVEAQQQrltLQRIIALVHAEQAYHQRAAEILDQLQDH 251 Physcomitrella patens subsp. patens
AAP06881     205 SALGREATAAMEAVEVQQQqvtFDRLLAMVDAERAYHQNAADILNKLHDE 254 Japanese rice
NP_567969    205 TILGKEAASALASVEDQQQkltLERLLSMVESERAYHQRVLQILDQLEGE 254 thale cress

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