Conserved Protein Domain Family
Peptidases_S8_10

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cd07494: Peptidases_S8_10 
Peptidase S8 family domain, uncharacterized subfamily 10
This family is a member of the Peptidases S8 or Subtilases serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.
Statistics
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PSSM-Id: 173819
View PSSM: cd07494
Aligned: 6 rows
Threshold Bit Score: 430.36
Threshold Setting Gi: 83593302
Created: 15-Apr-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
active sitecatalytic triad
Feature 1:active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                    #                                   #               
YP_723854    158 PDDICQGINAHRLHdqgitGSGVKVVMVDTGWYRHPf-FESHGYQGKVvldgg-avnpeLDENGHGTGESANLFaiapnv 235 Trichodesmium e...
YP_445143     90 PDEVATILRATRVHrngitGSKVEVAMPDTGFYEHEf-YERRGYRTRStilgpgasnpsQDNYGHGTGEAANIFaaapda 168 Salinibacter ru...
YP_001859897 196 PADVALKLNATPVHqqgitGKGVRIAMIDSGFAHGHpyFKAHGYASSVvlapg-atdrrTDGNGHGTGESANIFaiapga 274 Burkholderia ph...
YP_427054    140 PEDLSALLGARDLHqrgetGRGVRVAVVDSGFYAHPw-FGSRDLGVRVllapg-arapaCDEIGHGTMVCAALLslapga 217 Rhodospirillum ...
YP_001415995 171 PNDLANLLNASGPAvrgmsGAGVRVAMVDTGFSLDHpyFLNRRFSVLTapga----dgtRDRDGHGTAMCANLFaiapdi 246 Xanthobacter au...
ZP_03274624  162 PDCLAKGLNAKQAHdggidGRGVKVVMVDSGWYNHPf-FTHHNYQGQVilapg-stdkhIDANGHGTGESANLFavapgv 239 Arthrospira max...
Feature 1                              #                      #                                  
YP_723854    236 ELTMVKakskk------salvnSVGAFKkavs----lnpDIISCSWGddqrdpp------------lsafakvMSAIVSD 293 Trichodesmium e...
YP_445143    169 QLIPVKmg------------ndAVGAFNkacn----qspDIITNSWGwsvdspgtswsdirnrsrslyntlkaMEAAIAN 232 Salinibacter ru...
YP_001859897 275 TFIGVKldneadpssgasvlegLQEALKhd--------pQVISVSLGydlrgpgntp------lktlpnglvaLEAEIQA 340 Burkholderia ph...
YP_427054    218 QVTLVKqng----------ddeVFVAFKlals----lspDIVQNTWGyslaegr------------lgaaedlIAATLED 271 Rhodospirillum ...
YP_001415995 247 DFIGISlglp--------dgsvPIDALHggillalahqpDILVLSIAydlrsditdle-----aerlpgscvaLALQLQN 313 Xanthobacter au...
ZP_03274624  240 DFIMVKadvairg---kfrnvnSIAAFRtaia----qrpDIISCSWGsnqrsse------------lspynkvLAAVVAD 300 Arthrospira max...
Feature 1                     #                                                                  
YP_723854    294 AVNRGIIVVFSAGNGgwsf--pgqhPDVISAGGVymssdgkleasdy----asgfrsrifpqrTVPDVCGlvgklp---r 364 Trichodesmium e...
YP_445143    233 AVNNGIVVCFSAGNGpggygfpashPDVIAVGGVhvnypdldleass---yaasfdsslysgrQVPDLCGmvgddvsslp 309 Salinibacter ru...
YP_001859897 341 AVKRGIVIVFSAGNGhysf--pgqmPEIISAGGVfvdqngamrasdy----asaftsliysgrSVPDVCGlvgllp---h 411 Burkholderia ph...
YP_427054    272 AIARGILVVFAGGNGglly--psqrPEVLAIGGVfqgedgarqaasy----asgylsklfpgrRLPDFCAlvgmap---m 342 Rhodospirillum ...
YP_001415995 314 AVARGVTVVCAGGNGqfaf--pamlPEVIAAGGCvvdaggevrasni----asgfrsniypgrTVPDVCGiagsle---k 384 Xanthobacter au...
ZP_03274624  301 AVRRGIIVIFSAGNGhwsf--paqhPNAIAAGGVyqhldgptkgeleasnyssafhspvypgrQVPDVCGlvgqrp---h 375 Arthrospira max...
Feature 1                                                   #                                    
YP_723854    365 atyiMLPVQPGSlmdvtrgarnigypygdetlpkdgwAVFSGTSAAAPQLAGICALM-KQVYPQISPQQARDFLKKTARD 443 Trichodesmium e...
YP_445143    310 apllMLPVPPGSrldtsst-----------gaaddswGLFSGTSAAAPQVAGVVALMlEKNNSLSPSDVKKKLVNQAAKD 378 Salinibacter ru...
YP_001859897 412 atyiSLPVSPGCeidrenaaf-------dgttsndgwGVFSGTSAAAPQLAGLCALL-LQADPHLSPGDIKSILRRTARD 483 Burkholderia ph...
YP_427054    343 gvylAMPTQPGGqidrafaqqpyp--egddtpptdgwVVISGTSAASAQVSGLLALL-RARAPGLSQERARALLAKTARA 419 Rhodospirillum ...
YP_001415995 385 qaylMLPCPPGSwldrscaglp------dgtgvndgwCFTGGTSAAAPQVAAVCALM-LQANPKLTARDIRSVLNRTASD 457 Xanthobacter au...
ZP_03274624  376 aayiMLPVPPGSsndikcaefe------dgtepndgwAAFSGTSAAAPQVAGVCALL-KQLDPGLSPVRAKIILEKSAID 448 Arthrospira max...
Feature 1                      
YP_723854    444 IFTGKSSLSTGGNQ 457 Trichodesmium erythraeum IMS101
YP_445143    379 VTKGQSAMGDSAGP 392 Salinibacter ruber DSM 13855
YP_001859897 484 VTKGHANPASDPKG 497 Burkholderia phymatum STM815
YP_427054    420 VHHGASAQGNPAGP 433 Rhodospirillum rubrum ATCC 11170
YP_001415995 458 VAFGTSSAMTGGRA 471 Xanthobacter autotrophicus Py2
ZP_03274624  449 VVKGSSNYYFSRPT 462 Arthrospira maxima CS-328

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