3EMN,2K4T


Conserved Protein Domain Family
Porin3

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cd07303: Porin3 
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Eukaryotic porin family that forms channels in the mitochondrial outer membrane
The porin family 3 contains two sub-families that play vital roles in the mitochondrial outer membrane, a translocase for unfolded pre-proteins (Tom40) and the voltage-dependent anion channel (VDAC) that regulates the flux of mostly anionic metabolites through the outer mitochondrial membrane.
Statistics
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PSSM-Id: 132765
Aligned: 4 rows
Threshold Bit Score: 333.472
Created: 30-Sep-2008
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3EMN_X        18 TYADLGKSARDVFTKGYgfgLIKLDLKTksengleFTSSGSANTe-----tTKVNGSLETKYrwte---ygltFTEKWNt 89  house mouse
Q9QYA2        82 TFEECHRKCKELFPVQMe--GVKLTVNKgls--nrFQVTHTVALgtigesnYHFGVTYVGTKqlsp---teafPVLVGDm 154 house mouse
XP_001320195   3 SGTEYYESMNNLFDNKNf-pGIKFDVELnq---spETTINSSINirh-pyfNIIEKNSQTKIvpspiriaqvvLNHQTSk 77  Trichomonas vag...
2K4T_A         6 TYADLGKSARDVFTKGYgfgLIKLDLKTksengleFTSSGSANTe-----tTKVTGSLETKYrwte---ygltFTEKWNt 77  human
3EMN_X        90 dNTLGTEITVEDqla-rgLKLTFDSSFspn------------tgKKNAKIKTGYKRehINLGCDVDFdi------agPSI 150 house mouse
Q9QYA2       155 dNSGSLNAQVIHqls-pgLRSKMAIQTqq-------------skFVNWQVDGEYRG--SDFTAAVTLgnpdvlvgsgILV 218 house mouse
XP_001320195  78 lSNVILSLGQKNyisyqkSNSNKNTSVrcrcdftstsfipsillENNSKYHNFSIQ--AQTRDMIYI----------ALI 145 Trichomonas vag...
2K4T_A        78 dNTLGTEITVEDqla-rgLKLTFDSSFspn------------tgKKNAKIKTGYKRehINLGCDMDFdi------agPSI 138 human
3EMN_X       151 RGALVLGYegWLAGYQMNFEtsksrVTQSNFAVGYKTd----eFQLHTNVNDgTEFGGSIYQKVNkkLETAVNLAWTagN 226 house mouse
Q9QYA2       219 AHYLQSITpcLALGGELVYHr---rPGEEGTVMSLAGkytlnnWLATVTLGQ-AGMHATYYHKASdqLQVGVEFEAStrM 294 house mouse
XP_001320195 146 DTKMTLRYknFIFTYQNVRNcv-kgNTAYSILLHYKHgl--rdFQAAIMKDNfRTLTLRHKHEINdkLTVGASLTADs-N 221 Trichomonas vag...
2K4T_A       139 RGALVLGYegWLAGYQMNFEtaksrVTQSNFAVGYKTd----eFQLHTNVNDgTEFGGSIYQKVNkkLETAVNLAWTagN 214 human
3EMN_X       227 SNTRFGIAAKYQVDp-dACFSAKVNnsSLIGLGYTQTL-KPGIKLTLSALLDgknvnagGHKLGLGLEFQ 294 house mouse
Q9QYA2       295 QDTSASFGYQLDLPkanFLFKGSVNsnWIVGATLEKKLpPLPLTLSLCAFLNhr---knKFLCGFGLTIG 361 house mouse
XP_001320195 222 LNSKVELAWIAKVNd--AIIHSSIDtkLNVSTVYKQEL-YPQCNILVSTHLDhk---naQYNFGLGFQWV 285 Trichomonas vaginalis G3
2K4T_A       215 SNTRFGIAAKYQIDp-dACFSAKVNnsSLIGLGYTQTL-KPGIKLTLSALLDgknvnagGHKLGLGLEFQ 282 human
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