Conserved Protein Domain Family
ALDH_HBenzADH

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cd07151: ALDH_HBenzADH 
NADP+-dependent p-hydroxybenzaldehyde dehydrogenase-like
NADP+-dependent, p-hydroxybenzaldehyde dehydrogenase (PchA, HBenzADH) which catalyzes oxidation of p-hydroxybenzaldehyde to p-hydroxybenzoic acid and other related sequences are included in this CD.
Statistics
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PSSM-Id: 143469
View PSSM: cd07151
Aligned: 16 rows
Threshold Bit Score: 773.015
Threshold Setting Gi: 21221847
Created: 2-Jan-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                       
AAA75634     18 GEWRVGkagrdldvlDPFTQEkllqiplanreDLDEAYRSARQAQVAWAacGPSERAQVMLNAVRIFDERRDEIIDWIIR 97  Pseudomonas putida
ZP_02990684  12 GEWVNGsseksidnvNPFSNEtlfsiqsadeeDLNRAYEAAKASQTDWAdmLPQVRRELIEKFAQLTMDNKDFIVDWLVK 91  Exiguobacterium ...
NP_242876    12 GEWIEGastqtitnyNPYTGEkiheikgasldDLDQAYRAAKNAQKEWEqtLPAQKQEVLEKAAALLAERKDEVIERLVN 91  Bacillus halodur...
NP_691405    14 GEWRDGqgettyevkNPYNDEvlqeikmaskeDIDEAYKSAEQAKKKWAkfNPFERSSIMEKAVQIIDARREEFVNHLIR 93  Oceanobacillus i...
NP_388616    14 GKWQEGsspnvlenkNPYTQKtfttfrkatadDVDEAYRAAALAKKKWDavNPFEKRTILEKAVTYIEENEEAIIYLIME 93  Bacillus subtili...
NP_627626    15 GEWRPGtgswdiidfNPYDNEklasitiatvdEVDAAYRAAERAQRQWAatNPYARRAVFEKALRLVEEREAEIGEAIVA 94  Streptomyces coe...
NP_391762    13 GKWTGGesgrtedilNPYDQSvittaslatgkQLEDAFDIAQKAQKEWAksTTEDRKAVLQKARGYLHENRDDIIMMIAR 92  Bacillus subtili...
ZP_03227939  12 GEWQKGtgegtidvqNPFTQEsilsisaaskeDVKNAYEVAKLAQKDWKntLPQKKQEILYKAIDIVESERDVIVEWMIK 91  Bacillus coahuil...
NP_601867    17 GQWVEGnsdristniNPYDDSviaeskqasiaDVDAAYEAAKKAQAEWAatPAAERSAIIYRAAELLEEHREEIVEWLIK 96  Corynebacterium ...
NP_736689    26 NGWVDGtserstttlNPFNGEevatirnasqeDVDKAYATAAEVQKEWAavPPVKKARILNKAAQVIEDNRDAIVELIRR 105 Corynebacterium ...
Feature 1                                                                    #                  
AAA75634     98 ESGSTrIKAQIEWGAARAITQESASLPSrv-hGRILASdvpGKESRVYREPLGVIGIISPWNFPLHLTARSLAPALALGN 176 Pseudomonas putida
ZP_02990684  92 ESGSTrIKAESEFAASMAIIKEAATFPFrm-dGLIKPSivpNKENRVYRKPLGVIGIISPWNFPFHLAVRSIVTALATGN 170 Exiguobacterium ...
NP_242876    92 EAGSSiIKASIEWGATLQTIKVAATFPLrm-eGKILPSnipGKENRIYRSAKGVIGVISPFNFPLVLAMRSVAPALATGN 170 Bacillus halodur...
NP_691405    94 EGGSShLKANVEIDFVIAITREAASFPLrm-sGEIVPSlipGKENRIYRSPLGVVGVIGPFNFPMYLAMRSVAPALAVGN 172 Oceanobacillus i...
NP_388616    94 ELGGTrLKAAFEIGLVKNIIKEAATFPIrm-eGKILPStidGKENRLYRVPAGVVGVISPFNFPFFLSMKSVAPALGAGN 172 Bacillus subtili...
NP_627626    95 ELGGTrLKAAFELHLAKEFLREAVHLALap-eGRIIPSpvdGKENRVYRVPVGVVGVISPFNFPFLLSLKSVAPALALGN 173 Streptomyces coe...
NP_391762    93 ETGGTiIKSTIELEQTIAILDEAMTYTGelggVKEVPSdieGKTNKIYRLPLGVISSISPFNFPMNLSMRSIAPAIALGN 172 Bacillus subtili...
ZP_03227939  92 ETGSTfMKSMGEVDVSLNIMREAATYPFrm-eGKVLPSiteGKENRVYRDPLGVVGVISPWNFPFHLAVRSIITALATGN 170 Bacillus coahuil...
NP_601867    97 ESGSTrSKANLEITLAGNITKESASFPGrv-hGRISPSntpGKENRVYRVAKGVVGVISPWNFPLNLSIRSVAPALAVGN 175 Corynebacterium ...
NP_736689   106 ESGSTaLKANIEAGLAMASLREAATFPAri-tGQILPSntpGKSNYVFREPLGVVGVISPWNFPFALSMRSVAPALACGN 184 Corynebacterium ...
Feature 1                                                                                       
AAA75634    177 ACVIKPASDtPVTGGLLLAHIFEEAGLPKGVLSVVVGSGsEIGDAFVEHEvPGFISFTGSTQVGRNIGRIAAggeHLKHV 256 Pseudomonas putida
ZP_02990684 171 TAVVKPATAtPVTGGLLFASLFEEAGLPKGVLNVVVGRGsEIGDAIVEHPiPRLISFTGSTEVGQGIAEKAGr--LLKKT 248 Exiguobacterium ...
NP_242876   171 AVVLKCSSDaPITSGLLIAELFEEAGLPKGVLNVVVGKAaEIGDAFVTHPiPKLISFTGSTEVGRHIAQLAAr--ELKET 248 Bacillus halodur...
NP_691405   173 GVVLKPDDQtAVTGGILLAKVFEEAGLPKGVFNVVVPNIeDIGDAFVEHPiPRLISFTGSTPVGRHIGEICGr--NIKKV 250 Oceanobacillus i...
NP_388616   173 GVVLKPHEEtPICGGTLIAKIFENAGIPAGLLNVVVTDIaEIGDSFVEHPvPRIISFTGSTKVGSYIGQLAMk--HFKKP 250 Bacillus subtili...
NP_627626   174 AVVLKPHQNtPIVGGTLVAKILEDAGLPGGLLNVVVTDIaEIGDAFIEHPvPKVISFTGSDKVGRHVATVCAa--NFKRS 251 Streptomyces coe...
NP_391762   173 SVVHKPDIQtAISGGTIIAKAFEHAGLPAGVLNVMLTDVkEIGDGMLTNPiPRLISFTGSTAVGRHIGEIAGr--AFKRM 250 Bacillus subtili...
ZP_03227939 171 AVVVKPSTKsPVTGGLIFASIFEEAGLPKGLLNVVVGKSsEIGDEVIVNPiPRLISFTGSTDVGQHIGELAGk--HLKKT 248 Bacillus coahuil...
NP_601867   176 AVVIKPASDtPVTGGVIPARIFEEAGVPAGVISTVAGAGsEIGDHFVTHAvPKLISFTGSTPVGRRVGELAInggPMKTV 255 Corynebacterium ...
NP_736689   185 GVVLKPASDtPIVGGTLLAHIFEAAGLPTGLFNVVVGAGsEIGDYFVEHRiPRLISFTGSTPVGKQVGATATggkYIKKV 264 Corynebacterium ...
Feature 1         #                              #  #                                           
AAA75634    257 ALELGGNSPFVVLADADLDQAVNAAVVGKFLHQGQICMAINRIIVEdsvYDEFVNRYAERVKSLpYGDPSKPeTVVGPVI 336 Pseudomonas putida
ZP_02990684 249 ALELGGNNVFVVLDDADLDRAVESAVYSKFFHQGQICMSTNRILVAesiHDEFVERYVERVKQLkAGDPNEKdTQVGPLI 328 Exiguobacterium ...
NP_242876   249 ALELGGNNVMIVLDDADIEKAAEKAAVGKFLHQGQICMALNRIIVDasiYDSFVEVFKEKVSQLqTGNPAEPaTLIGPLI 328 Bacillus halodur...
NP_691405   251 ALELGGNNPLVVLEDAKVENAVNSALFGKFMHNGQICMAINRIIVHkdiYEEFVEKFVEKAKKIkVGNPSEKdNLIGPLI 330 Oceanobacillus i...
NP_388616   251 LLELGGNSAFIVLEDADIEYAVNAAVFSRFTHQGQICMSANRVLVHssiYDKFLELYQAKVESLkVGDPMDPdTIIGPLI 330 Bacillus subtili...
NP_627626   252 VLELGGNSALVVLDDADVDYAVDAAVFSRFVHQGQVCMAANRVLVDravADEFTEKFVAKVSGLkVGDPRDPsTVIGPVI 331 Streptomyces coe...
NP_391762   251 ALELGGNNPFAVLSDADVDRAVDAAIFGKFIHQGQICMIINRIIVHqdvYDEFVEKFTARVKQLpYGDQTDPkTVVGPLI 330 Bacillus subtili...
ZP_03227939 249 ALELGGNNVFIVLEDADIEQAVESALFGKFYHQGQICMSINRFMIDekiANDFTEAFLKRVKELeFGDPSAKtTHIGPLI 328 Bacillus coahuil...
NP_601867   256 ALELGGNAPFVVLADADIDAAAQAAAVGAFLHQGQICMSINRVIVDaavHDEFLEKFVEAVKNIpTGDPSAEgTLVGPVI 335 Corynebacterium ...
NP_736689   265 ALELGGNAPMVVLSDADINKAVAAASMGSFLHQGQICMAVNRIIVEapvYDQFLEGFAARVSKVaYGDQLDDaTMVGPIV 344 Corynebacterium ...
Feature 1                                                                                       
AAA75634    337 NAKQLAGLQDKIATAKseGARVMVEGEAqGNVLPPHVFADVTadMEIAREEIFGPLVGIQRARDEAHALELANSSEYGLS 416 Pseudomonas putida
ZP_02990684 329 DHDQVDRILDQIEKTVdaGATVHTGGTAdGNVLEPTVLSGVTndMPLAKNEIFGPVAVILSFKDDEEAARLSNELPYGLS 408 Exiguobacterium ...
NP_242876   329 NYKQIGRIQQLVKESVaqGAVKVLEGHVqGNLMSPTILSEVTndMPVAKEEIFGPIAPIIKAKDEAEAIAIANDSPYGLS 408 Bacillus halodur...
NP_691405   331 NRQAIDRILEQIESAKeqGAEVVLEGKVeGNVMHPYILTGSNd-VATAQNEMFGPVATIISAESDEEAIRIANDTPFGLS 409 Oceanobacillus i...
NP_388616   331 NSRQTDGLMKTVEQAIeeGAVPVKLGGFnGTIVEPTILKDVKpfMSIAKEELFGPVVSFMKFDSEDEAVDIANETPFGLS 410 Bacillus subtili...
NP_627626   332 NSSQADALSGVVEQALaeGATALVRGSVtDNLVEPSVLTGLPadSALLRQEVFGPVAFLVPFDGEEEAVRLVNDTPYGLS 411 Streptomyces coe...
NP_391762   331 NERQIEKALEIIEQAKtdGIELAVEGKRvGNVLTPYVFVGADnnSKIAQTELFAPIATIIKAGSDQEAIDMANDTEYGLS 410 Bacillus subtili...
ZP_03227939 329 SRDQVDRILDLVEESTkeGATLLHGGQAeGNVLEPTILTDVKqsMSIVQNEIFGPVAAIMTFQSEDEVLSLANELPYGLS 408 Bacillus coahuil...
NP_601867   336 NDSQLSGLKEKIELAKkeGATVQVEGPIeGRLVHPHVFSDVTsdMEIAREEIFGPLISVLKADDEAHAAELANASDFGLS 415 Corynebacterium ...
NP_736689   345 NDSQVESVSGKIDLAReqGARAVVSGPIeGRVIAPHVFADVTpdMELFREEIFGPVVGVVKADNEEHALELANDTEFGLS 424 Corynebacterium ...
Feature 1                                                                           
AAA75634    417 SAVFTSsLERGVKFARgIRAGMTHINDIpVNDEPNAPFGGEKNSGLGRFNGDWAIEEFTTDHWITVQH 484 Pseudomonas putida
ZP_02990684 409 GAVHGS-VYRATNFARkVETGMIHINDQsVNDEPHMPFGGEKNSGLGRFNGEWVLEEFTTLQWVSIMH 475 Exiguobacterium sp. AT1b
NP_242876   409 GSIFTGsLHRGVQVAKqIDTGMIHVNDQpVNEEAHISFGGEKDSGIGRFGGEWVLDKFTTVKWISIQE 476 Bacillus halodurans C-125
NP_691405   410 GAVHAGsPERGVEVAKqITSGMVHVNDQsVNDEPLIAFGGEKASGLGRFGGKWSLEEFTTVQWISVQT 477 Oceanobacillus iheyensis HTE831
NP_388616   411 GAVHTSnLERGVAFAKrIETGMIHVNDTtINDEPNVAFGGEKQSGLGRLNGEWSLEEFTTLKWISVQH 478 Bacillus subtilis subsp. sub...
NP_627626   412 GAVHTGdVERGVNFAKrIDTGMFHVNDGtVHDEPIVPFGGEKHSGLGRLNGDTMLDAFTTQKWISVQH 479 Streptomyces coelicolor A3(2)
NP_391762   411 SAVFTSdLEKGEKFALqIDSGMTHVNDQsVNDSPNIAFGGNKASGVGRFGNPWVVEEFTVTKWISIQK 478 Bacillus subtilis subsp. sub...
ZP_03227939 409 GAIHSRdLDRAMRIAReVETGMIHINDQpVNDEPHMPFGGEKKSGLGRFNGEWALEEFTTVKWVSIQR 476 Bacillus coahuilensis m4-4
NP_601867   416 AAVWSKdIDRAAQFALqIDSGMVHINDLtVNDEPHVMFGGSKNSGLGRFNGDWAIEEFTTDRWIGIKR 483 Corynebacterium glutamicum A...
NP_736689   425 SAVFTEdLQRGINFARrVEAGMTHINDItVNDEAHVMFGGEKNSGLGRFNGEWAIDEFTTDHWVSVTT 492 Corynebacterium efficiens YS...

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