Conserved Protein Domain Family
ALDH_y4uC

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cd07149: ALDH_y4uC 
Uncharacterized ALDH (y4uC) with similarity to Tortula ruralis aldehyde dehydrogenase ALDH21A1
Uncharacterized aldehyde dehydrogenase (ORF name y4uC) with sequence similarity to the moss Tortula ruralis aldehyde dehydrogenase ALDH21A1 (RNP123) believed to play an important role in the detoxification of aldehydes generated in response to desiccation- and salinity-stress, and similar sequences are included in this CD.
Statistics
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PSSM-Id: 143467
View PSSM: cd07149
Aligned: 26 rows
Threshold Bit Score: 655.05
Threshold Setting Gi: 33597690
Created: 2-Jan-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
Q53197        58 IAVHSPYDGSLLGsveatdpaDIDRLLATARRGAEISRnLPRHKRASILEGAAQMVESRHDAFAEIIVREAGKtIVQARK 137 Rhizobium sp. N...
YP_552843     17 QSLTDKYHGNEYGrmavasaaQVTQAVDGALAGFRAST-LSPYERFRILMEAARIVESRMPMLIDLMRDEAGFtHADGEN 95  Burkholderia xe...
NP_885333     31 FPVLDKYTLAPAAevsrasrrQVAQAVSQCKAAADRGA-PAARERAAILRRAAGLLDAYRQDFEAVMMVEGGFtVHDISA 109 Bordetella para...
YP_922622     29 LEVRAPYGGELLAriaestpdEVDAAVTLAARTFARNE-LTPHERADILRRTSQLIAQRAEEFAHSVVAEAGKpLRDARA 107 Nocardioides sp...
YP_886517     29 TTLTAPFDGRELAvipv-ggrRDVERAVQAAHNARRTG-LPLDRRLTILEAVAASIAARSEDFARAIALECAKpIKTARA 106 Mycobacterium s...
NP_213133     19 IEVIYPYTRKPIGrvpkgdekDVEKAIERAKEGFKEIFsLTAYERYEILMRAAQLLKERAEEFAKTLVLEVGKtIREART 98  Aquifex aeolicu...
YP_002121209  19 LDVIYPYDNTKIGksyvvndsYVEKAIEKAKIGLKKLSsLSAFEKYEILYKTSELLRKNKEEIARTIVYEVGKtIKEARV 98  Hydrogenobaculu...
ZP_01855572   30 IDVINPFDQSVIDtipqgsgdDVLKAVSVLEQGARIMKsMTAYDRSLILQKASELMLERKDDFARTISLEEGKiLAESQV 109 Planctomyces ma...
NP_694161     22 QEIKNPFTGEVIGeqyfaqsdDVEIALATAYKGKKQVKnIPIIERSKILKKAAYLLEENKEKFAKLLSSELGKpLKDTLG 101 Oceanobacillus ...
NP_242604     23 IEVIDPGTNHVIAtvpaateaDAKAAIEAAKEGAEIARqMPIHERAAILKRTAEIVTRDRELFAQTIAKEGSKtIREARS 102 Bacillus halodu...
Feature 1                                                             #                          
Q53197       138 EVLRCVNTLKLSAEEAKrNAGEIVPFdaytGSEQRQGWFTRDPLGIITAITPYNDPLNLVAHKLGPAIAGGNAVMLKPSN 217 Rhizobium sp. N...
YP_552843     96 EVRRCVQTFELSAEEGKhLAGELVPMeaaaGVRNRMGFTIRVPRGVVCAITPFNSPLNTLAHKVGPAIAGGNAVVIKPSN 175 Burkholderia xe...
NP_885333    110 EFTRAKVTLELSADEALrLTGSMVPFqaspGAEHKLGFTVRVPVGVVAAITPFNAPLNTVLHKVAPAFAAGNSVVLKPSA 189 Bordetella para...
YP_922622    108 EVARAVLTFELCAQEATrLAGEVVPVegtpGSENRRAFTIRRPAGVVCAITPFNGPVNQLSHKVPTAIAAGCTVVVKPAE 187 Nocardioides sp...
YP_886517    107 EVLRAIDTIKFSVAAARtLGSESVPLdataAGAGKVTFTKRVPVGVVAAIAPFNFPLNLVVHKVAPALAVGCPVVLKPAT 186 Mycobacterium s...
NP_213133     99 EVQRAIQTLIFSAEEAKrVNGETFPIdahpNGKGKLGFYIRVPVGIVSAITPFNFPLNLSMHKVAPALAAGNAVILKPSE 178 Aquifex aeolicu...
YP_002121209  99 EVDRAIETFRFSAEEAKrIYGKTYPVdahpNGKSKFGFYIRVPAGIVVAISPFNFPLNLTAHKVGPAIAAGCPVIVKPSE 178 Hydrogenobaculu...
ZP_01855572  110 EATRSAEVIRLSGEEARrMTGEMIPLegnaGGQNKLGFTLRIPCGIVAAITPFNFPLNLVCHKVGPAIAAGNAILIKPAS 189 Planctomyces ma...
NP_694161    102 EVDRSIETLELSGEEAKrLHGETIPGssseRGLNTIASIYRVPVGVVAAITPFNAPLNLVCHKVGPAFAGGNVTLLKPAP 181 Oceanobacillus ...
NP_242604    103 EVRRCIETLTLSGEEAKrLHGETIPFsqmpGHERRVGYFYRFPIGIIVAITPFNDPLNLVAHKIGPAIAAGNSLIIKPSS 182 Bacillus halodu...
Feature 1                                                                             #          
Q53197       218 lTPFSAIKLVGALREAGLPEEVITISHGDREl-VTAMIAAReVRMVSFTGGFATGEAISRAAgLKKLAMELGGNAPVIVM 296 Rhizobium sp. N...
YP_552843    176 vTPLSAVELCKVLIDAGLPANLLALVHGSGSaiGRQLLADPrIAFYAFTGSTQVGREIQQAAgLRGMQLELGSIASTIVC 255 Burkholderia xe...
NP_885333    190 fTPLTSALLARVLLEAGMPPEFLAVVQGEGDdvGTWLLEEQdVAFYTFTGSTRVGRIIQRAAgLRRTQMELGSIASTIVC 269 Bordetella para...
YP_922622    188 vTPLSAIKVVQAMLDAGLPPGHVTVVQGRGEtvGQQLLEDPrFAVYSFTGSTAVGAHIRRTVgLRKTLLELGNNSANIVH 267 Nocardioides sp...
YP_886517    187 qTPLSALLLAEVFHEAGLPAGWLNVVCGSGAevGGALATHPdVAYVTFTGSPQVGWGIAEAApKKKVRLELGSNAPLIVD 266 Mycobacterium s...
NP_213133    179 rTPLTPLMLGEILLEAGVPPKALSVIPGYGDv-GKAMTTHPdVRVVSFTGSRKVGDIIARQVgIKKLVLELGSNSAIILH 257 Aquifex aeolicu...
YP_002121209 179 kTPLSPIIMGELLLEAGLPKEAISVLPGYGGl-GKALTTHKdVRVVSFTGSKMVGELIAKQAgIKKLVLELGSNSALVIH 257 Hydrogenobaculu...
ZP_01855572  190 dTPLSALKLTELLLEAGLPKEAIACITGPGGeiGRAICTDTrIRKISFTGSYEVGTKICEMAgLKKVTMELGSNSPVIIM 269 Planctomyces ma...
NP_694161    182 qTTLIATAFLQLLFEAGFPKNAIHMLLGGVDv-GQQIVKDErINVISFTGGLVASRNISQIAgIKKTLFELGGNAATIVH 260 Oceanobacillus ...
NP_242604    183 fTPLSALRLVKALEEAGLPKKIVQVITGHGSviGPTLTKHRdVRLISFTGGYETGEKIARSAgVKKLAMELGSNSPTIVL 262 Bacillus halodu...
Feature 1                            #  #                                                        
Q53197       297 NDcDFDKAVEGCVSGAFWAaGQNCIGAQRILIQselYGRFRDAFVAATKKLkAGDPLQEdTDVGPMISKQVAERTEAAVN 376 Rhizobium sp. N...
YP_552843    256 EDaDIDLAIPKIVNAGFRKaGQVCTSVQRLFVArgiADEFIPRFVAAVKATpYGDPADPkTILGPMISVQHAQRAAAWVR 335 Burkholderia xe...
NP_885333    270 ADaDLEAAVPRIANAAFRKaGQVCTSIQRLYVEdalKNELIERLSRYLDDMpAGDPRAVaTRVGPMISEAAATRAQAWIA 349 Bordetella para...
YP_922622    268 ADaDLGLAAKVLAKSSTAYaGQVCISAQRILVHedvFEEFSALLADQVSALsVGDPSDEgTDVGPMISLDAARRAEQWVA 347 Nocardioides sp...
YP_886517    267 REsDWEAAADQAVFGAFVQaGQSCVSTQRIFVHedvVDAFTERMAAATRGLvVGDPLDEtVDVSAVINEGEAIRVEKWIA 346 Mycobacterium s...
NP_213133    258 KDgNLEKAVEKTVQGGYAIaGQVCISVQRVFVHedlYDEFIKRLKERVSKLkVGDPMNEdTDLGPMIAPSELERIQEWIS 337 Aquifex aeolicu...
YP_002121209 258 KDaDLEKAATKAVQGGFSMaGQVCISIQRIFVHeyvLEPFLRLLEEKISNIkIGDPMDEeVDMGPMIDKNQVERVKQWIK 337 Hydrogenobaculu...
ZP_01855572  270 DDaDLEKAATAVSMAGYANaGQVCISAQRILTSsaiKSDFVDLLKSKVDVLhTGNQLEEtTKIGPMVRETDATRVEQWVN 349 Planctomyces ma...
NP_694161    261 QDaDIETAARLCAKTGYSNsGQSCISVQRIYVQeeiKDNFIELLKQEVSKLkVGDPLDPhTDIGTLVDEKAAGRVIEWIN 340 Oceanobacillus ...
NP_242604    263 QDaELMEAVASCVSGAFCAaGQNCIGVQRIYVEqsvFNSFIQSFVAQTKQLrLGDKQSEeTDIGPMISEKEAKRIERWVE 342 Bacillus halodu...
Feature 1                                                                                        
Q53197       377 EAikaGATLLCGNYRe-----GSLYHPTVLEGTpltCRLWHEEVFAPVVMLAPFDtLDKGIEMANDPDYSLHAGIFTNdL 451 Rhizobium sp. N...
YP_552843    336 EAldgGARLLTGGKCe-----GALFEPTVLHGVdatMKVVCQEVFAPVVSIIEFDdIGEAVAGANASDFGLAAGLFTSdL 410 Burkholderia xe...
NP_885333    350 EAveaGARLVRGGERq-----GAVVQPAVLADVpesCSAWSTEVFSPMVSVRGFArFDDVLASANDTPYGLAAGIFTNdH 424 Bordetella para...
YP_922622    348 QAiddGAKLVCGGSRd-----GQFFVPTVVARPaahSALACQEAFAPVAVLIAYRtLREAIDIANSTEYGLQAAVFTEgL 422 Nocardioides sp...
YP_886517    347 EAeagGAKVVVGGGRs-----GAVVTPTIIRGVdpaAKVQCQEVFGPVVTVNSFAeFTEALAAANDSVFGLNAGVFTTnL 421 Mycobacterium s...
NP_213133    338 EAvqkGAKIEAGGLRca--edETIFSPTIVSLVpedSKLFKEEAFAPVVAVNPYKdIEEAIRWVNSSDYGLQVGVFTNdV 415 Aquifex aeolicu...
YP_002121209 338 EAmekGAKVVQKAKNienikgTNYLLPTLLLDVdkdSTIFKEEAFAPVVNINRYKdIDEVVNIINEGDYGLQIGVYTKdI 417 Hydrogenobaculu...
ZP_01855572  350 EAvsqGARLVTGGTRq-----GAIYAPTILDNTnpeMQVEKDEIFGPAVALSYFDdIEHAIQMANNTNYGLSAGIFTQdL 424 Planctomyces ma...
NP_694161    341 EAvesGAEIIQGGTKn-----GASVEPTVLFNPpkkSKVVCEEVFGPIVSVIPYKnIEEAIQESNDSPFGLQTGIFTNqI 415 Oceanobacillus ...
NP_242604    343 EAkeeGARVLTGGRRt-----GAYFEPTVLTNVspsSRLAKEEAFAPIVIIEGVHsLTEAIARANDVDFGLQAGLFTNnL 417 Bacillus halodu...
Feature 1                                                                  
Q53197       452 NVALEAANrIEVGGVMINDSsdYRFDAMPFGGFKYGSMGREGVRFAYEDMTQPKVVCI 509 Rhizobium sp. NGR234
YP_552843    411 KTAFRTAReLAFGGVHINEAssARIDVMPFGGVKDSGFGREGPAYAIREMTEERLITV 468 Burkholderia xenovorans LB400
NP_885333    425 ARIMSAVRsLRFGTVHINETssARCDVMPFGGVKDSGFGKEGPGYAAREMTEERLIVF 482 Bordetella parapertussis 12822
YP_922622    423 DVAMAVARrLDVGGVIVNDAssYRVDSMPYGGVKHSGTGREGVRYAVEEMTESQLVVL 480 Nocardioides sp. JS614
YP_886517    422 RHALQAIEeLEFGSVYINDVptVRADQQPYGGVKESGNTREGPRYAMEEMTELKFITL 479 Mycobacterium smegmatis str. MC2 155
NP_213133    416 KLAWKCIKeIEAGGVLINEGptFRADHMPYGGVKYSGIGREGPKFAIEDYTEIKTVIF 473 Aquifex aeolicus VF5
YP_002121209 418 NMAMEFVRkCEVGGVNINEGpnFRVDHMPYGGFKFSGIGREGPSFAIEDYTEIKNVLI 475 Hydrogenobaculum sp. Y04AAS1
ZP_01855572  425 DRAMKFAReVESGNLHINWSsqWRADAMPYGGLKHSGTGKEGPKYAIQEMSEEKMVVI 482 Planctomyces maris DSM 8797
NP_694161    416 DLAYRVADeMEVGGIVINGTsnFRLDHLPYGGVKNSGIGREGPRYALEEMTESKMVVL 473 Oceanobacillus iheyensis HTE831
NP_242604    418 TAAFSAIEkLEVGGIMVNDSsdVRIDAMPFGGIKKSGLGREGVRYAIEEMTEQKVVAF 475 Bacillus halodurans C-125

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