Conserved Protein Domain Family
ALDH_PhpJ

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cd07146: ALDH_PhpJ 
Streptomyces putative phosphonoformaldehyde dehydrogenase PhpJ-like
Putative phosphonoformaldehyde dehydrogenase (PhpJ), an aldehyde dehydrogenase homolog reportedly involved in the biosynthesis of phosphinothricin tripeptides in Streptomyces viridochromogenes DSM 40736, and similar sequences are included in this CD.
Statistics
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PSSM-Id: 143464
View PSSM: cd07146
Aligned: 9 rows
Threshold Bit Score: 647.109
Threshold Setting Gi: 111225712
Created: 2-Jan-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
AAU00094      14 TTVHDRWTGEPVGtvp---rdGAEEAAAAVAALAAGRRa-TTPQQRSAVLTRAADMLTARAEEFSTLITAESGVcrkETL 89  Streptomyces vi...
YP_716506     20 AEVRNPYTDEVVGtvv---raSPEQALEAARGLAGVRSe-LTAYDRSNILTATAELLHRERDDFASTISQESGLaimDAR 95  Frankia alni AC...
AAT47201      11 LLIKNPYTGETIHel----evDSISAISEIIDTSYNYRshLSRSQRADILKKCAMYLEKDKDEAASLITSETGLskkDTC 86  Edwardsiella ic...
ZP_02358218   28 LIVSNPYDGEAIAel----plENGDDARRKLQTAARFTstLSRHDRIAVFEKAIALLAAEKRDASILITLESGLcrkDTM 103 Burkholderia ok...
YP_550033     35 IEVKHPYSGKIVAtv----pkATLDDVRRALRIARDYRstLTRHDRYRILMKAGELVAHRRDEIARLITLESGLclkDTQ 110 Polaromonas sp....
ACB13626      24 IEVLYPYTDEVVGtv----paGTAEHARKAFEIAANYKskLTRYERSEILKKAGRLIGEKREDLAKWLTLELGIchqHAI 99  uncultured alph...
YP_001613189  26 ILVRYPFTGEVIGsv----prLDEGTVLEALASVSSGPprLSRHERSEILLRAAAHIEAQAGAVARLITWESGLclkDTA 101 Sorangium cellu...
ZP_02930899   20 LEVFNPWDGSRVGsv----arITRSQLDEVIASHLAPHgpLTRYERATILNRTHDLLNGRREELARIITREAGLclkETR 95  Verrucomicrobiu...
ZP_01166002    5 YSLVNPFDNSPLGeyeytpwaTLENQLAMLKEGQLSQRk-TAAFQRAGVLNKLAALLKEHSEEMATLITQETGKtilDSR 83  Neptuniibacter ...
Feature 1                                                               #                        
AAU00094      90 REVSRAAGNLRVAAAEAeriRGESIPLpd----gtRLAVTLPEPV-GVVLGITPFNRPLNQVVVKAAPALAAGCPLLLKP 164 Streptomyces vi...
YP_716506     96 REVDRAATQLRYCAEEGkriTGEAIRTdvtsarqrRLAITTREPI-GVVCAVTPFNRPLNQVVTKVAPAIAANNRVVVKP 174 Frankia alni AC...
AAT47201      87 YEIGRTINVLLSGVNEIlssEESIMDCdlyegfkeRKIISIREPLdGIIYAITPFNHPINQVAHKVIPAIATNNRIILKP 166 Edwardsiella ic...
ZP_02358218  104 YEIERVINVLRAAIAELnrdDSQTFSCdnattadkRKIFTVREPLrGVVAAITPFNHPMNQIAHKICPAIASNNRVVLKP 183 Burkholderia ok...
YP_550033    111 YEVGRASDVMLFAANQAlvdDGQVFSCdltahgksRKVYTLKEPLlGAITAITPFNHPLNQVIHKIAPAVATNNRVVLKP 190 Polaromonas sp....
ACB13626     100 YETKRAQDVYDFAAAQVlndDGEIFSCdlthngkaRKIFTKREPV-KAISAITPFNHPLNMVSHKIAPSIATNNCMVCKP 178 uncultured alph...
YP_001613189 102 YEVRRALDVLRFSAYEAlrdDGQCLAFdisangkpRRGYTLREPL-RLVTAITPFNHPLNQVAHKVAPSVASGSSMVLKP 180 Sorangium cellu...
ZP_02930899   96 YEVGRACDVFSFAAMEAlrdDGQTFSCdisptgkaRKIFTHREPL-SLVAAITPFNHPLNQVAHKLAPAIAAGAPIILKP 174 Verrucomicrobiu...
ZP_01166002   84 VEMMRAYNAAIASAEEArqiQGESLDSdayapaggKIGVVCWKPL-GTILCITPFNFPINIAIHKIGPAYAAGNTILFKP 162 Neptuniibacter ...
Feature 1                                                                               #        
AAU00094     165 SEKTPLTALAFAELLVEaGCAKDMLAVVTGEPGevGPPLAAHPdVAMVTFTGSVATGHAVAAQAAGKRQLLELGGNDPLF 244 Streptomyces vi...
YP_716506    175 SEKTPLSAIRLVDALLRsGLPPDLIALVCGEPGelVDALIHSGhIDMLTFTGSTRVGRLLAASAGMIRQTYELGDSGALV 254 Frankia alni AC...
AAT47201     167 SEKTPLSAIYFRDLLYKcGLPKEMFSLVIGNPKilYERMISDLrISMVTFTGGVDVGKSIACTAGYRKIVLELGGNDPLI 246 Edwardsiella ic...
ZP_02358218  184 SEKTPLSALYLLDLFREaGLPEPMFDVVIGAPDvvGAELVRNDqVELVAFTGSVAVGKRIAEMAGYRRTILELGGNDPLI 263 Burkholderia ok...
YP_550033    191 SEKTPLAAYLIADILYEaGLPPQMLSVVTGDPAeiADELLTSPdVDLVTFTGGVAIGKYIAGKAIYKRQILELGGNDPII 270 Polaromonas sp....
ACB13626     179 TELTPLTCLALADILYEaGLPPEMFQVVTGLPQdiGEEMITNEnIDIITFTGGVPVGKIIADKAGYKRQALELGGNDPLI 258 uncultured alph...
YP_001613189 181 SEKTPLSAIYLASVLHEsGLPPGMLSVVTGDPAeiGRALVTHPaVELVSFTGGVEIGKRIASLLGYRRAVLELGGNDPLI 260 Sorangium cellu...
ZP_02930899  175 SEKTPLTAARLAEVLYEaGLPGWMLSVVHGSLEeiTTPLIQDErVELVTFTGSASVGKKIAATAGYKKLCLELGGHSPMI 254 Verrucomicrobiu...
ZP_01166002  163 GPQNTASAQLLVKLCYEaGMPENTLQLCMPEFSd-LDRLNAHPdVNAINFTGGTAAANAISAAAGYKKLLLELGGNDPLI 241 Neptuniibacter ...
Feature 1                                 #  #                                                   
AAU00094     245 VLPDa---DLRRAAKLAADGSCATAGQSCRGIKRVFVWeeVADEFTALLEPAVAAKrAGDPRREdTDLGPLVSEEAALVV 321 Streptomyces vi...
YP_716506    255 IMADa---DIPAAVAAATAGAFATSGQSCRGVKRIIAHedVADEFVRELAAAASALvVGDPGDPaTDIGTLIDRHAASEV 331 Frankia alni AC...
AAT47201     247 IMPDa---DLERATDLVVRGSYSNSGQRCTAVKRVLAHksIVHDLNYLVAEKSKAWvTGDPMQSaTMMGTVIDEEAAIRI 323 Edwardsiella ic...
ZP_02358218  264 VMEDa---DLDRAAQLAVKGSYKNSGQRCTAVKRILVErtVAGRFTELLVEHSRRWkIGDPMDEhVDIGTLIDDAAAIEC 340 Burkholderia ok...
YP_550033    271 VMDDa---DIEEAATLAASGSYKNSGQRCTAIKRILVQesVADRFVELLVEKTRALkYGDPFDPaMDMGTVIDEPAAIHF 347 Polaromonas sp....
ACB13626     259 ICNDlsdaDLEKAATIAVAGATGNSGQRCTAIKRILVQesVADRFVPLVLEKAKKIkFGDPQNPaTELGCVIHSTAAELF 338 uncultured alph...
YP_001613189 261 VLDDa---DLDEAVRLAAYGCYRNSGQRCTAVKRLIVSerVADELAGRLAAASAQIkVGDPLDPaTDMGTVISEAAARQL 337 Sorangium cellu...
ZP_02930899  255 ILEDa---DLDLAAKLACEGSFRNSGQRCTAVRRLLVHekVIQEFTDRFVKLAATYvHGDPAEEsTVVGTVIDEPAAIAL 331 Verrucomicrobiu...
ZP_01166002  242 VMDDg---DLEAATTAAINHRFATAGQRCTAAKRLFIHanVYEAFRDLLVEKSSKLvVGDPMKDdTFVGPVINQGAADQI 318 Neptuniibacter ...
Feature 1                                                                                        
AAU00094     322 ERRIARAVrdGARLVTGGERdGALVRPAVLDHVppdTELVTEETFGPVAPVIRVRd-ADEAVRLSNGTAYGLQAGVLTRd 400 Streptomyces vi...
YP_716506    332 EARVARAVaaGARVLCGARRvGAQYWPTVLDHVprdADLVRLETFGPTAPVIRVKd-FPEAVEVVNDSRYGLQAGIFTNn 410 Frankia alni AC...
AAT47201     324 QNVVNGAIdqGARLLSGNQRnGALLSPTVLTNVdpkMQLVTQETFGPVTPIITFEt-ISEAIAIANSTAYGLSSALCTNr 402 Edwardsiella ic...
ZP_02358218  341 ARRVDEAIdaGARVLLGHRRdGAAYAPTVLDRVdpaLRLVQQETFGPVSPVIAFSg-LDEAVAIANSTRYGLSSGVCTNr 419 Burkholderia ok...
YP_550033    348 EKVVNEAIaqGAKLLVGNVRrGALYAPTVLDHVrpgMTVVREETFGPVSPVIRFKt-LDEAIAIVNGTAYGLSSSLCTNr 426 Polaromonas sp....
ACB13626     339 ENRVLDAEkqGAKILYHPGRqGALLPPIVIDYVpheCELVMEETFGPIIPIVRVPdnDEEVMAISNSTEFGLSSGVCTNd 418 uncultured alph...
YP_001613189 338 EAAAEDTLarGARLLFGNERrGALYGPTVMDHVprdAPSVQRETFGPHAPILRVRd-IDEAIAVANGTSYGLSAGVCTNd 416 Sorangium cellu...
ZP_02930899  332 EGAVLEAVgkGAAVLLGGSRqGAQMAPTILENVprsAYLATNECFGPLAPIFPVKd-LDDALEFSNATAYGLSSAIVTNs 410 Verrucomicrobiu...
ZP_01166002  319 RTLIEQAIedGASVALGNQYeGAFVYPTILENVsptSEIMVEEAFGPVMPLYKFEs-VEEIIPIINNTAYGLQAGVFSQn 397 Neptuniibacter ...
Feature 1                                                                    
AAU00094     401 sAAFWDIAArLRVGAVNLGEGPHFDSPHIPFGGVKSSG-VGREGIRYAIAEMTVTKTVTL 459 Streptomyces viridochromogenes
YP_716506    411 lEHARRAAElFDVGAVVVNGGPQFESPNIPFGGVKDSG-IGREGARYAIEEMTRVKTLVI 469 Frankia alni ACN14a
AAT47201     403 lDWIKEFSSrLNVGTMNVWEVPGFRTELSPFGGIKDSGlGLKEGVRESMKNYTNIKTISL 462 Edwardsiella ictaluri
ZP_02358218  420 lDYITHLIAnLDVGTVNVWEVPGFRLESTPFGGVKDSGlGSKEGMQEAIKNFTNLKTYSL 479 Burkholderia oklahomensis EO147
YP_550033    427 lDTITRVVQeLHVGSVNVREVPGYRLEMTPFGGIKDSGlGYKEGVLEAMKSFCNTKTYSL 486 Polaromonas sp. JS666
ACB13626     419 lHRAISYINgLDVGTCNIWEQPGYRIETSPFGGIKDSGnGVKEGVTEAMKFFTNVKTYSL 478 uncultured alpha proteobacterium 01...
YP_001613189 417 lGRVHRLVReLRCGTVNVREVPGYRSELSPFGGIKDSGiGIKEGVVEAMKAMTNVKLYTV 476 Sorangium cellulosum 'So ce 56'
ZP_02930899  411 mDAVIKTVKtLKVGTVNVNEIPGYRLELSPFGGVKDSGlGIKEGVIEAMKFMTTVKTFSL 470 Verrucomicrobium spinosum DSM 4136
ZP_01166002  398 lATIKELYEqLDVGTLAANDGPGFRTEHFPFGGVKESG-IGREGIKYAIREMSYTKTLVI 456 Neptuniibacter caesariensis

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