Conserved Protein Domain Family
ALDH_CddD_SSP0762

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cd07138: ALDH_CddD_SSP0762 
Rhodococcus ruber 6-oxolauric acid dehydrogenase-like
The 6-oxolauric acid dehydrogenase (CddD) from Rhodococcus ruber SC1 which converts 6-oxolauric acid to dodecanedioic acid, and the aldehyde dehydrogenase (locus SSP0762) from Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 and other similar sequences, are included in this CD.
Statistics
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PSSM-Id: 143456
View PSSM: cd07138
Aligned: 63 rows
Threshold Bit Score: 573.295
Threshold Setting Gi: 33599734
Created: 2-Jan-2009
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
NAD bindingcatalytic
Feature 1:NAD binding site [chemical binding site]
Evidence:
  • Comment:based on similarity to structure 3B4W: the Mycobacterium tuberculosis aldehyde dehydrogenase with bound NAD

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
AAL14238       9 LYINGSWVAStsktvieVLNPATEEVIGTVPDgtaaDVDAAVAAARAAFDGWa---sTPVDKRAQYLRAIAAGIADRSDE 85  Rhodococcus ruber
ZP_01616382    7 FYIDGQWTAPhgkhvlsILNPATSVPCVAMACa---NETDVNAAAEAAFRAFpawsaTPSDQRALLMMGIADEMENRADD 83  marine gamma pr...
ZP_01078613   12 VYIDGNWRRTkstqlysLINPATQDSIAQVTMasvkDVEDAVAAAHKAFASWs---nTSAQTRANYMNAIADEMQTRYQD 88  Marinomonas sp....
YP_267145      7 LYINGDWQLPntedtidVINPANSELCAKTPSasiaDVDKAIAAAKYAFAQWs---aTTPAERSQLITAIADEMQNRIDD 83  Colwellia psych...
YP_001508807  31 IFIDGEWVSSagtgtltVINPATEEPLATLPRghvdDVDRAAQAAARAFESWs---rSTVDDRIDMLTRIADILDTRAEE 107 Frankia sp. EAN...
ZP_00632263   13 NFVGGKWIPAqatgeieVINPTTEEVFAVVPEgtagDVAPAVEAAATAFPGWs---eTTIEQRADMLRKFARLTEARAEE 89  Paracoccus deni...
ZP_00632219    6 ILVGGTWVPSeaearieAINPATEEVVARIPDgtsgDVDRATAAAVASFERWs---qSSLDERKAVLNRLADLIDRDREP 82  Paracoccus deni...
YP_001508740   7 IYLDGTWVTPdgteevsVPNSTTGKEIGTIRLgsekDVTAAVEAARTAFTTWs---dTPIAERIRILDEMTRILTSRHSE 83  Frankia sp. EAN...
YP_001264776  10 YLAGGAWIEAtanppipVVNPANGAVIGEAPCctadDVDRAVAAARAALPGWa---aTPVADRLARLSALREALAARGDE 86  Sphingomonas wi...
NP_733724     25 HWIDGRAVTGsgp-lidVVNPADESVIAHLHEatadDVDMAVDAAVAAIPGWa---aTPPRHRADVMRRLAEGLQKRSEE 100 Streptomyces co...
Feature 1                                                                     #####              
AAL14238      86 LARTISAEMGAPlsfAQAMQVPLPINSFSHAAAVaeSFPFErt--eGSSVIVREPIGVVGAITPWNYPLHQIAAKVAYAL 163 Rhodococcus ruber
ZP_01616382   84 LVQAHVETMGIPrhqAMEVQIAGPIDAMRYFASLaaTMGEPed--rGGYLISHEPVGVCALINPWNYPLLQMIGKVAPAL 161 marine gamma pr...
ZP_01078613   89 LIEAHVLSMGCPahlVGAYHLDCAIDAMRYYAKL--AFNMEketrrESVLLTQKAIGVCALINPWNYPLHQLVGKLAPAL 166 Marinomonas sp....
YP_267145     84 FASAISTSMGCPkhlAFDIQVQGAIDAFRGYADMtsYVDESst--eHGVMQCHSAVGVCVLINPWNYPLSQLVGKIGPAL 161 Colwellia psych...
YP_001508807 108 LARTIVSEVGTPitlARGSQSATAINDLRIAAASlkDIVWEer--fDDTIVRRIPAGVAGAITPWNGPMRMIALKAGAAI 185 Frankia sp. EAN...
ZP_00632263   90 LTFTGVSEVGQPaaaARVFQTQGAVGELDLMAEIlpEMDWNip--eGKAVVRRVAGGVVGAITAWNGPLRSVISKAGAAM 167 Paracoccus deni...
ZP_00632219   83 LLRNMVAESGLPitpAGRSQVDGASDELRLMAEVvdQIDWAth--yGSSRVVRQAAGVTGAITAWNAPLRSIISKAGAAI 160 Paracoccus deni...
YP_001508740  84 LSDLFSQEVGTPtaqAGAFQGLATSLFGMYAQKAs-TFDYEdr--rGNITVLREPIGVVGAITPWNFPLLLMCLKVAPAL 160 Frankia sp. EAN...
YP_001264776  87 LALLITRQMGTPigfSRAAQIGLPLRTFDITIAA--MAALEee-rtARSRILRDPAGVVAAITPWNFPLHQIAAKVVPAL 163 Sphingomonas wi...
NP_733724    101 LAATITLEMGAPiafSRQAQVGFPVASTLAAIAAaeRFEWSer--iENSLVVREPVGVVGAITPWNFPLQQLVTKVVPAM 178 Streptomyces co...
Feature 1                #                                    #             ####  #  #           
AAL14238     164 AAGNTIVVKPSEvaPLNAWMLAEIIDaAGVPAGVFNLVSGTGpvVGEALASHHeVDMISFTGSTNAGKRVSELAAqtVKR 243 Rhodococcus ruber
ZP_01616382  162 AAGCTMLAKPAEqtPTSDIIMAEIFDkVGLPAGVFNLITGLGaeVGPLMASHPrVDMVSFTGSNRSGISVAIEAAptVKR 241 marine gamma pr...
ZP_01078613  167 AAGCTLIEKPAEqtPLTDLIMAEIMHkVGLPAGVFNLIFGHGheIGPLLAEHPkVNMVSFTGSTRAGIEVAKNAAssVKR 246 Marinomonas sp....
YP_267145    162 ATGCTIVAKPAEqtPLQDLILAEIFDkVGVLAGVFNVITGYGfkIGEHLCSHPdVDMVSFTGSTGAGIKVAQAASttVKR 241 Colwellia psych...
YP_001508807 186 AAGCTMVLKGTEvaPLSAFLFAEAAAeAGLPRGVFNLVSGTGpeIGEALATHPlVDIVSLTGSVRAGSRVMELASrsVKR 265 Frankia sp. EAN...
ZP_00632263  168 AAGCTVVVKPSEvaPMTAYIFAEICEeAGLPPGVFNLVSGTGpvVGEAIVAHPaVDIVSLTGSVRAGRRVMEVAAqdIKR 247 Paracoccus deni...
ZP_00632219  161 AAGCTVVVKPSEvtPLSAIALADLFGeAGAPDGVFNLVLGRGpvIGEAIASHPdIEVVSLTGSVRAGQRVMELASrmVKR 240 Paracoccus deni...
YP_001508740 161 AVGCTAVLKPAHiaPLSAYALAEAADaAGLPRGVLNVVPGGPr-AGEALVAHPdVDMISFTGSTKAGRRISAVAGetIKR 239 Frankia sp. EAN...
YP_001264776 164 AAGCTVVLKPSEitPLDARIFAELVEgCGFPAGVFNMLFGAAe-TGAALVAHPqVDMVSFTGSTAAGRHIGAQAGrdLKK 242 Sphingomonas wi...
NP_733724    179 LAGNTVVLKPSElsPLSARMFAEIATeAGLPNGVFNVVQGTGpvVGEALSRHPkIDMISFTGSTRAGKSVSSAASvtVKR 258 Streptomyces co...
Feature 1           ###                               #                                          
AAL14238     244 VALELGGKSANIVLDDaDIDELMPNAVQWAMINsGQTCSALTRLLVPraiLTEAETAAKTIAEAYtvgapddpdtTLGPL 323 Rhodococcus ruber
ZP_01616382  242 VCQEMGGKSALIITEDaDLHTAVRYGVENVMLNtGQTCDALTRMLVPasrYQEAIDQAVIVADEQvvgdpddpltTMGPL 321 marine gamma pr...
ZP_01078613  247 VCQELGGKSAFIITQDaDIEAAVRYGVEDVMANtGQTCNALTRMLVPksqYQKVIEVAKQVALEHtvgdprlaetNMGPL 326 Marinomonas sp....
YP_267145    242 VCQELGGKSPFIITDDaDLAAAVRYGVEDVMINsGQTCCALTRMLVPeslYQQAIVIAKAVAEENvvgdpqdenvTMGPL 321 Colwellia psych...
YP_001508807 266 VALELGGKSANIILADaDLEKAVVDGLGDAFRNsGQVCGGLSRMLVPrgrLAEAEEIAAAKATSYvigdpldeatTLGPV 345 Frankia sp. EAN...
ZP_00632263  248 VHLELGGKSANILFEDaDIDHAISVGIEDAFRNaGQVCGGLTRILVPrtlLAKVEEAAKAKAESFvigdpfdpatTLGPV 327 Paracoccus deni...
ZP_00632219  241 VHLELGGKSANVVLRDaDVERAVQVGIEDAFRNtGQACGALTRVVVPrpsLAKAEAAAVAKVESYvvgdpmdpatTIGPV 320 Paracoccus deni...
YP_001508740 240 VTLELGGKSALVVLDDaDLQAAVTTGMQSVTTNnGQGCACLTRVVVPrarLAEAEEMARAFAESTvigdprdpatTLGPM 319 Frankia sp. EAN...
YP_001264776 243 AALELGGKSANILLDDaDLSVAVPQAIGQCFVNgGQTCAALTRLIVPrakRAAVEALAVEAAARWlpgdpeqpstRLGPL 322 Sphingomonas wi...
NP_733724    259 VALELGGKAAHIVLPEaDLDSAVARGLAFAWANaGQACGAYVRMLVPedlQTAVVDRLRTAAQEYvvgdpadeatRIGPL 338 Streptomyces co...
Feature 1                                                                 # #                    
AAL14238     324 VSATQLKRVRGYIDRGvqEGATLITGGSEpveglavGYYVKPTIFSEVtpdMTIHREEIFGPVLSIAPYDtEEDAVRIAN 403 Rhodococcus ruber
ZP_01616382  322 ASEQQCQRVRDYIKQGiaEGARMVAGGAElptslegGAYVLPTLFADVrndMVIAREEIFGPVLCIMSYEtIDEAVDIAN 401 marine gamma pr...
ZP_01078613  327 ASAKQHQVVKDYIQLGleEGASLLTGGAElperldkGYYIKPTIFTQVtpeMRIAQEEIFGPVLCILTYDdIEEAITIAN 406 Marinomonas sp....
YP_267145    322 SSSLQQKRVLDYINIGikEGAELVTGGPEiparlqqGAYVMPTIFTNVtndMTIAQEEIFGPVLCMIPYSdEQEAIKIAN 401 Colwellia psych...
YP_001508807 346 VSDAQRDRVRRYIQTGvdEGLRLVAGGPEapehldrGYYVQPTVFTGDn-sSRLAQEEIFGPVVIIIPFDdTDEAVAIAN 424 Frankia sp. EAN...
ZP_00632263  328 ATAAARERIRGYINLGqrQGARMITGGAEppmglnrGFFVKPTVFSGDn-sMRIAQEEIFGPVVVIIPFDgEDDAVRIAN 406 Paracoccus deni...
ZP_00632219  321 ATASQFRRVRDYIDIGqaEGARLLVGGSDrpkglnrGYYVNPTVFTGDn-fMRIAREEIFGPVVVIIPYEdETEALQIAN 399 Paracoccus deni...
YP_001508740 320 ASAEHRDRVDGYIRTGidEGARLVSGGPGapdrwsgGFFVRPTVFTVEdvsATIAQQEIFGPVQVLIPHDgDDDAARIAN 399 Frankia sp. EAN...
YP_001264776 323 SSLRQRERVAAMVARAleDGATALIGGTAapegfekGAWFAATVLSGVtpaMEIAREEVFGPVLVILDHDgEEDAIAIAN 402 Sphingomonas wi...
NP_733724    339 ASETQRRRVDDYIRRGiaDGATLVTGGPGrpegfetGAYVRPTIFSDVapeSVIAQEEIFGPVLVVIPYTdDEHAVEIAN 418 Streptomyces co...
Feature 1                                                  #                            
AAL14238     404 DSEYGLRGGVWSRdVDRARAVAArMRTGQVMINGGeFNPNAPFGGYKQSGTGREFGTHGLEEFLEIKSLQF 474 Rhodococcus ruber
ZP_01616382  402 DSEFGLSSGVFAAnDSDAIAIARrMRAGQCFIQGGfFRLEAPFGGYKQSGNGREWGEAGLAEYQEIKAIIR 472 marine gamma proteobacte...
ZP_01078613  407 DSQYGLSSAVYAKdAETALAIAKrLEAGQSYIQGSyFSMHAPFGGVKQSGNGREWGEEALEEYVETQAIIY 477 Marinomonas sp. MED121
YP_267145    402 DTVFGLSSGVFAKdANAALQIARkIRAGQSYIQGTyFNSHAPFGGFKQSGNGREWGVEGLREFIEVQSIII 472 Colwellia psychrerythrae...
YP_001508807 425 DSDYGLAGAVWAAdPARARDVGRrIRTGRVRINGApIDMRAPHGGLKRSGIGREMGRYGIEEYLEYQSLIS 495 Frankia sp. EAN1pec
ZP_00632263  407 DSAYGLAGGLWCRdVERARAIARrIRTGRVRINGTpLEKRAPHGGFKHSGIGREWGRYGIEEFLEYQSIIG 477 Paracoccus denitrificans...
ZP_00632219  400 DCDYGLAGAVWAAdTDRARAFAQrMRAGRIRVNGTaISKYAPHGGFKLSGIGREWGRYGIEEFLEYQSIHG 470 Paracoccus denitrificans...
YP_001508740 400 ATVYGLAGAVFGTdPDRIRRVTRlMRTGKVDINGTtFDPEAPLGGYRQSGNGREFGDYSLEEFLETKAVAD 470 Frankia sp. EAN1pec
YP_001264776 403 DSAYGLSGGVWSAdPARAERVAArLRTGQVMINGAmLDMEAPFGGVGQSGIGREYGRYGLEEYFNLKAITG 473 Sphingomonas wittichii RW1
NP_733724    419 GTVYGLNAAVTGD-EDHAMAIAVrLRVGQVDVNGGrHNFQAPFGGYKQSGNGREMGRAGLEEFLETKAITS 488 Streptomyces coelicolor ...

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