Conserved Protein Domain Family
ALDH_EutE

?
cd07121: ALDH_EutE 
Ethanolamine utilization protein EutE-like
Coenzyme A acylating aldehyde dehydrogenase (ACDH), an NAD+ and CoA-dependent acetaldehyde dehydrogenase, acetylating (EC=1.2.1.10), converts acetaldehyde into acetyl-CoA. This CD is limited to such monofunctional enzymes as the Ethanolamine utilization protein, EutE, in Salmonella typhimurium. Mutations in eutE abolish the ability to utilize ethanolamine as a carbon source.
Statistics
?
PSSM-Id: 143439
View PSSM: cd07121
Aligned: 21 rows
Threshold Bit Score: 611.934
Threshold Setting Gi: 198256520
Created: 1-Jan-2009
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
putative
Feature 1:putative catalytic cysteine [active site]
Evidence:
  • Comment:conserved cysteine that aligns with the catalytic cysteine of the ALDH superfamily

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
P77445        31 GVFasLDDAVAAAKVAQQgl---kSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTPGVEcL 107 Escherichia col...
YP_066775     38 GVFdeLDDAVAAAKAACKli---dTVAMRTRVVEVMRRAARMNARPLAEKAVAETGMGNIEDKVLKTLLVANSTPGPEiL 114 Desulfotalea ps...
ZP_01222600   34 GIYptLDGAVAAAKSAQRei---rTLALRDDIILAVRRTAKKHAKELSEMAVAETGFGRVEDKVAKHLLVAHRTPGTEiL 110 Photobacterium ...
NP_865037     37 GIFgnASDAVAAARRAFEqlr-qrPMEDRKRVIDIIRKISIENCEELGLMEMRETGIGRPEHKIEKLRALGELSPGTEfL 115 Rhodopirellula ...
ZP_01855336   39 GVFrsVDQAVAAATAGQKqll-naTLADRAKALEIVRQICTSQADELGRMEMEETKIGRLDHKIEKLHLIKSIPGMEF-L 116 Planctomyces ma...
Q716S8        35 GVFenVENAISSAVHAQKilslhyTKEQREKIITEIRKAALQNKEVLATMILEETHMGRYEDKILKHELVAKYTPGTEdL 114 Clostridium bei...
ZP_02169447   60 GVFpdVDQAVHAAAGSQKewv-krPVSERRVILEAMKQTVDSQKERYSELAVEETGLGNVADKIAKHELIITKTPGVEdL 138 Bacillus seleni...
NP_464690     36 GVFdtVDEAVQAAVIAQNsyk-ekSLEERRNVVKAIREALYPEIESIAARAVAETGMGNVADKILKNTLAIEKTPGVEdL 114 Listeria monocy...
YP_001311120  16 GVFssVNDAVLAAVGAYNqys-kfTLNERQEIINSIKEKLLSRVEEIAYMTVEETGMGNVHDKIEKLILAIKKTPGIEdL 94  Clostridium bei...
CAJ87625      29 AIFqtVDEAVCAAHQAFLrfq-qcPLKTRSAIISAIREELMPRLTELAEESASETGMGNKEDKYLKNKAALNNTPGIEdL 107 Escherichia coli
Feature 1                                                                                        
P77445       108 SPQVLTGDnGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAPHPaaKKVSQRAITLLNQAIVAAGGpeN 187 Escherichia col...
YP_066775    115 QPTAITGDdGFTLIENAPWGVIASVTPSTNPGSTVINNGISMISGGNAVVFAPHPaaKRITQEAIKLMNKAIAEETGinN 194 Desulfotalea ps...
ZP_01222600  111 VPQAVSGDaGMSLMENAPWGVIASVTPSTNPSCTVINNAISMIAAGNAVVFAPHPaaKKVSQYAIQLVNKASESVGGpaN 190 Photobacterium ...
NP_865037    116 QTKAFSGDhGLAIIERAPFGVIAAITPVTHSLPTITGNAVSMIAGGNAVVVNPHPsgRLVAAEGVRRFNEEIAREVGidN 195 Rhodopirellula ...
ZP_01855336  117 KTEAVSGDyGVSLTEYAPFGVIGAITPVTHSLPTLACNFINMVAAGNTLVVNPHPggAKIACEGVRRFNRAIYQATGlqN 196 Planctomyces ma...
Q716S8       115 TTTAWSGDnGLTVVEMSPYGVIGAITPSTNPTETVICNSIGMIAAGNAVVFNGHPcaKKCVAFAVEMINKAIISCGGpeN 194 Clostridium bei...
ZP_02169447  139 RTDAVSGDhGLTIEEDAPFGVIGAVTPVTNPTTTVIHNSLVMLAAGNAVVFNVHPssKATCQRVVSDLNAAIKDAGGpqN 218 Bacillus seleni...
NP_464690    115 YTEVATGDnGMTLYELSPYGVIGAVAPSTNPTETLICNTIGMLAAGNAVFYSPHPgaKNISLWLIEKLNTIVRESCGvdN 194 Listeria monocy...
YP_001311120  95 ITEVRTGDnGMTLYELSSYGVICAIHPCTNPCATLISNTIGMLAAGNGVVHCPHPraIKVSKYVTEIISIAIRERCGidN 174 Clostridium bei...
CAJ87625     108 TTTALTGDgGMVLFEYSPFGVIGSVTPSTNPTETIINNSISMLAAGNSVYFSPHPgaKYVSLKLITTIEDIAFRCSGihN 187 Escherichia coli
Feature 1                                                                                        
P77445       188 LLVTVANPdietaqRLFKFpgigLLVVTGGEAVVEAARKHTnKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNI 267 Escherichia col...
YP_066775    195 LLVCIKEPsldaaqRLFTYpginLLTVTGGEAVVKAARKVTdKRLIAAGAGNPPVVVDETADLARAAESIYIGASFDNNL 274 Desulfotalea ps...
ZP_01222600  191 ICTSVATPslenaqALFTYpgigLLVVTGGDAVVDAARKVTdKRLIAAGPGNPPVVVDETADLERAAISIVQGASFDNNI 270 Photobacterium ...
NP_865037    196 LICVIAEPtlesaaELFGHrdvaLICVTGGPAVGRAALNSG-KRAIVAGPGNPPVVVDETADLDNAARCIIQGGAYDNNL 274 Rhodopirellula ...
ZP_01855336  197 LVTIVETPtletadEIFNHrgipLLVVTGGPGVARAALAAK-KRAIVAGPGNPPVVVDETADIENAAKSIIIGAAYDNNL 275 Planctomyces ma...
Q716S8       195 LVTTIKNPtmesldAIIKHpsikLLCGTGGPGMVKTLLNSG-KKAIGAGAGNPPVIVDDTADIEKAGRSIIEGCSFDNNL 273 Clostridium bei...
ZP_02169447  219 LITMIAEPtldtlnQLAGHqeirLLVGTGGQGLVRSLLQSG-KKAIGAGAGNPPVIVDETADIEAAAKAIILGASFDNNI 297 Bacillus seleni...
NP_464690    195 LVVTVEKPsiqaaqEMMNHpkvpLLVITGGPGVVLQAMQSG-KKVIGAGAGNPPSIVDETANIEKAAADIVDGASFDHNI 273 Listeria monocy...
YP_001311120 175 LVVTLNENsitctnEIMTHpdisMVVTTGGNNVLRQAMASG-KKVIGAGPGNPTTIVDETGDIKKAARDIVRGASFDNNI 253 Clostridium bei...
CAJ87625     188 LIVTVSEPtfaateQMMAHpkisVLAITGGPGIVAMGMKSG-KKVIGAGAGNPPCIVDETADIVKAAEDIINGASFDYNL 266 Escherichia coli
Feature 1         #                                                                              
P77445       268 ICADEKVLIVVdsVADELMRLMEGQHAVKLTAEQAQQLQPVLLkniderg-----------kgtvsrDWVGRDAGKIAAA 336 Escherichia col...
YP_066775    275 ICANEKEIIVVesVADQFKREFVAAGAFEISLEQAEAIGKTVLldygtd------------kcranpKWVGRDAYKLAEL 342 Desulfotalea ps...
ZP_01222600  271 VCATEKEIIAVasIADELKAQMCRHGAYEVTPEQAEAIARVVLkcypgd------------kptanpKWVGRDAAKLAEA 338 Photobacterium ...
NP_865037    275 LCIAEKEVFVVdsVFDDMMAAMRRAGAVQLDQAQIAKLTSVAItqvgddn-----------hdaaakDFIGKDASVLAAA 343 Rhodopirellula ...
ZP_01855336  276 LCIGEKEVFAVesIFDQLMSAMGRHGGFQLNAQQVEQLTSLAFappkepg----------ghailnrDLIGKDAAVLAGM 345 Planctomyces ma...
Q716S8       274 PCIAEKEVFVFenVADDLISNMLKNNAVIINEDQVSKLIDLVLqknnetq-----------eyfinkKWVGKDAKLFLDE 342 Clostridium bei...
ZP_02169447  298 LCIAEKEVFALdvIYDDLIYHLLQEGAYMLSESELSQVMKTVLvgdapieaakscsvsvrpdlhiakAWVGKEASAILKA 377 Bacillus seleni...
NP_464690    274 LCIAEKSVVAVdsIADFLMFQMEKNGALHVTNPSDIQKLEKVAvtdkg---------------vtnkKLVGKSASEILKE 338 Listeria monocy...
YP_001311120 254 MCISEKSIVAVssIADLLVEELVRNKVYYVDNDEEMLKLTVATltsdm---------------tlnkTLEGKSANEILKA 318 Clostridium bei...
CAJ87625     267 PCIAEKSLIVVasVADYLIQQMQSFGALLLNHEQTEKLRAICLpdgs-----------------ankKLVGKSPSALLEA 329 Escherichia coli
Feature 1                                                                                        
P77445       337 IGLKVPQETRLLFvet--taeHPFAVTELMMPVLPVVRVANVadAIALAVKLEGGCHHTAAMHSRNIENMNQMANAIDTS 414 Escherichia col...
YP_066775    343 IGVTIPAGCKLLFvdvkgdarHPFAVTEQMMPLIPVVRARNFdqALEWALMLERGLSHTAGLHSTNIHNMERMAKAVNTS 422 Desulfotalea ps...
ZP_01222600  339 AGIDVPADTRLLIfda--dksHVFAVIEQMMPILPLIRAANAdqAIDWAVELESGNRHTAAIHSKNIDVLTRMAYEMDCS 416 Photobacterium ...
NP_865037    344 AGVKVPESCELIFget--dehHPFVSVEQMMPFIPFVRARDVdhAIAMAKHYEHGFRHTAIIHSRNVHNMTKMGKELDTT 421 Rhodopirellula ...
ZP_01855336  346 IGVSVPAGTELLYget--dtnNPFVPEEQMMPFVPFVRCRNAdhGIELAKEFEHGFRHTSMIHSRNIETITKMGRIMDTT 423 Planctomyces ma...
Q716S8       343 IDVESPSNVKCIIcev--nanHPFVMTELMMPILPIVRVKDIdeAIKYAKIAEQNRKHSAYIYSKNIDNLNRFEREIDTT 420 Clostridium bei...
ZP_02169447  378 ATGKDLPVKLLICdve---atHPFVQLEQMMPVLPIVRMPDFdaAVEAAVKAEKGNRHTAVIHSKNVDRLTQFARRIETT 454 Bacillus seleni...
NP_464690    339 AGIACDFSPRLIIvet--ektHPFATVELLMPIVPVVRVPNFeeALEVAIELEQGLHHTATMHSQNISRLNKAARDMQTS 416 Listeria monocy...
YP_001311120 319 AGIVCERDIKLIVvnt--ikqHPFATVEMLMPLVPLIRVKNFeiALDTALEIEQGFRHTATIHSQSIERLNVAAKVMQTA 396 Clostridium bei...
CAJ87625     330 ASLPLPAKAPRLLiavv-dadDSWVTCEQLMPMLPIVKVNDFdsALALALKVEDGLHHTAIMHSQNVSRLNLAARVMQTS 408 Escherichia coli
Feature 1                                                       
P77445       415 IFVKNGPCIaGLGLGGEGWTTMTITTPTGEGVTsARTFVRLRRCVLV 461 Escherichia coli K-12
YP_066775    423 LFVKNGPHIaGLGAGGEGWTSMTISTPTGEGVTnAATFVRLRRCALV 469 Desulfotalea psychrophila LSv54
ZP_01222600  417 LLAKNGPAIaAIGAGGEGWTTMTISTPTGEGVTnALTFTRKRRCTAV 463 Photobacterium profundum 3TCK
NP_865037    422 LYVKNGPCMaALGLGGEGYLSFSIAGPTGEGVTtPDTFTRERRCSMI 468 Rhodopirellula baltica SH 1
ZP_01855336  424 LFVQNGPCGaALGNGGEGYASFSIATPTGEGVTnPMTFTRFRRSTTV 470 Planctomyces maris DSM 8797
Q716S8       421 IFVKNAKSFaGVGYEAEGFTTFTIAGSTGEGITsARNFTRQRRCVLA 467 Clostridium beijerinckii
ZP_02169447  455 IFVKNASSLaGVGFGGEGYATMTIAGPTGEGITsPRTFTRKRRCVLA 501 Bacillus selenitireducens MLS10
NP_464690    417 IFVKNGPSFaGLGFRGEGSTTFTIATPTGEGTTtARHFARRRRCVLT 463 Listeria monocytogenes EGD-e
YP_001311120 397 VFVKNGASLvGIGCNGEGDTSFTIATITGEGTTtARHFARRRRCSLT 443 Clostridium beijerinckii NCIMB 8052
CAJ87625     409 IFVKNGPSWaGIGVGGEGFTTFTIATPTGEGTTsARTFARSRRCVLT 455 Escherichia coli

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap