Conserved Protein Domain Family
ALDH_AldA-AAD23400

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cd07106: ALDH_AldA-AAD23400 
Streptomyces aureofaciens putative aldehyde dehydrogenase AldA (AAD23400)-like
Putative aldehyde dehydrogenase, AldA, from Streptomyces aureofaciens (locus AAD23400) and other similar sequences are present in this CD.
Statistics
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PSSM-Id: 143424
View PSSM: cd07106
Aligned: 49 rows
Threshold Bit Score: 571.009
Threshold Setting Gi: 89056280
Created: 12-Dec-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:catalytic residues [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
AAD23400      19 VVDPATGETFDEAPDqq-pgELDDVVARAQRAWHGWr-aDPAARTAALRGAADAVETAGDDLARLLTREQGKPl---aES 93  Streptomyces au...
ZP_01169854   33 RENPAHPEEIAGYAPvntkeEAIKAIDAAYDAFSGWkvsKVEDRVERMERAIRKIKDATPEIAELLSREHGKAl---wDS 109 Bacillus sp. NR...
AAF75990      21 VVSPADIRVLLGSVPdaapgQVDEAVAAAAMAFPEWssrPLEERQGALLAAAGTIHDMIEEYAPILSRENGKIl---eES 97  Mycobacterium v...
YP_511731     49 IYNPARPDELVGHAAaadadDVDAAVRAADAAFPAWssrTYTERAELLIAIADALSSDDADVARRSRLFCREHgkilrET 128 Jannaschia sp. ...
EDZ44744      20 VINPATEEVFARVPHas-eaHMNEAVAAAKAAQKAWaetPMRERRAKVEALAAAIGEEADELARLITMEQGKPl---pEA 95  Rhodobacterales...
YP_001262562  22 VVNPALGKPFARCPKad-raILDQAVAAAKRAFPGWaatPVDERARLLTGIADALAEKVDEFAAVLTAEQGKPl---dQA 97  Sphingomonas wi...
YP_295673     22 VVNPATGEVFTTVARat-erEAAAAIAAAKAAQPAWgslALEQRRALLLRFADELEANAEDLAASLVLEQGKPl---aEA 97  Ralstonia eutro...
CAJ88625      28 VENPALGEVFAHTPGct-pqQFDAVLDDAVRARPGWaatPLDVRREHLLACHRALLAVVEPMADLLTREQGKPl---rHA 103 Streptomyces am...
YP_001507606  21 VVNPATGEVHADAPDcd-egQLNEAFDAAAKAFTDWr-tDEDARRSILREASKRLSAAADRIAPVLTAEQGKPl---rSA 95  Frankia sp. EAN...
EDY80708      17 VINPATELPFASAPLcg-eqELEDAVSSAQTAFPKWa-aSERDRRAALHACANSIAANSDELARLITFEQGKPl---nEA 91  Verrucomicrobia...
Feature 1                                                            #                           
AAD23400      94 YAEIARTAARLRYFADLap-rTRRIDdg---rpVHSEVRWRPLGPVAAIVPWNFPLQLAAAKFAPALAAGNTVVLKPSPf 169 Streptomyces au...
ZP_01169854  110 KGEIAVSLMWMEFACQNv--kEVTEPqvkehdnGRTLITYDPIGVVSAITPWNYPISLSTIKIAPALLTGNTMVLKPSPf 187 Bacillus sp. NR...
AAF75990      98 HVDLEFASGICGYTAGIs--aEILADqqirdtgGTTLIRRRPIGPVAAITPWNFPVVLAFLKLAPALVAGNTVVLKPAAn 175 Mycobacterium v...
YP_511731    129 HLELSRLGDRFRLSASYa--eRLAADetlqgppFDTIITRQPRGVAALIVPWNWPLSILGAKLPQALMAGNTVVVKPSHn 206 Jannaschia sp. ...
EDZ44744      96 QGEVAWSQGYLAHTATLel-pDRVIQdd---aeFRIETRHKPLGVVAGIIAWNFPLLLCCWKIGPALMAGNAIVLKPAPt 171 Rhodobacterales...
YP_001262562  98 AGEVKGAVNVLRTFAAMrl-ePKVLRdd---arQRIVEHRVPLGVVAGIMPWNFPLVLLINKLGPALMTGNTMVAKPAPt 173 Sphingomonas wi...
YP_295673     98 RQELQFAQAFVRHIAGLsl-pVSVVQdd---atHRIELHHKPLGVVAAIAAWNFPVLIAAYKLAPALLMGNTVVLKPAPt 173 Ralstonia eutro...
CAJ88625     104 RAEVRLAADWFAHTARLdlspQRLVDep----aVRVALERVPHGVVAAIAPSNYPVLLAVCKIAPALLAGNTVVLKPSPd 179 Streptomyces am...
YP_001507606  96 HMEVLGAGYWLRYFSRLei-pREVIQdd---ehVRAEVVHRPMGVVAAITPWNFPIMLSAWKLGPALLAGNTVVLKPSPf 171 Frankia sp. EAN...
EDY80708      92 VSEVAYAVEVLNEYAILkv-pSVDLSls---pkTRSLLLNRPFGIVGLMTPWNFPLGTIAVKLAPALLAGNVVILKPSPn 167 Verrucomicrobia...
Feature 1                                                                             #          
AAD23400     170 TPLATRMLGSVLAtALPEDVLTVVTGREp-lGARLASHPgIRHVTFTGSVPTGRAVAGAAAaSLARVTLELGGNDAALLL 248 Streptomyces au...
ZP_01169854  188 APLAVSRVVEIIAsEFPPGVLNLVHGEAd-vGVELTSNPkVAKIAFTGGTKTAKSIMKAASeTIKKMTLELGGNDAAIVL 266 Bacillus sp. NR...
AAF75990     176 SPLVLAEIIRALQqHFPPGVLNMVTGGDa-vGEALVAHPrIRKIGFTGGIDTGRKVMAAAArDIKRVTLELGGNDPAILL 254 Mycobacterium v...
YP_511731    207 SALAPSQTLRIIAeMLPPGVLSVVTGSAsdiGDPLVRHPlVRFVNFTGSVEVGRHVMRQAAdNLTPVTLELGGNDAALIC 286 Jannaschia sp. ...
EDZ44744     172 TPVAALKLGEICArIFPAGLVNIITDANd-lGPKLTAHPdVAKIGFTGSSETGKRIMASAAdTMKRVTLEMGGNDPAIVL 250 Rhodobacterales...
YP_001262562 174 TPLTTLMFGELCRdVLPAGVLNIICDENd-lGGALSSHPdIAKVSFTGSTATGKKVLASTAeTLKRVTLELGGNDAAIVL 252 Sphingomonas wi...
YP_295673    174 TPLATLQMGAILKdIFPAGVVNIITDANd-lGSFLTSHPdIAKVSFTGSTATGKKVMASAGpGLKRITLELGGNDAAIVL 252 Ralstonia eutro...
CAJ88625     180 TPLSSLMMGDTFReVLPAGTFAVVGGGTe-lGARLTVHPaVRLVSFTGSVDTGRAIARQAAaDLKRIVLELGGNDPAVVL 258 Streptomyces am...
YP_001507606 172 TPLSTLLMGEILSeVLPPGVLNVVSGGDq-lGRWMTSHPvPRKISFTGSTGTGKHIAASAApDLKRLTLELGGNDAAILL 250 Frankia sp. EAN...
EDY80708     168 APLSPLLLGKLLNkILPAGVLNTLSGSKe-lGEAIARHPkIRKLSVTGSISTGKSILKNAAsEIKSVTLELGGNDPAIVL 246 Verrucomicrobia...
Feature 1                              #  #                                                      
AAD23400     249 DDv--DVDRIADRLFWAAFRNcGQVCMAVKRVYVParLHAEVVEALAQRAKTVa-vGPGLDpgtRLGPVNNARQLARVEQ 325 Streptomyces au...
ZP_01169854  267 PSfdvNDGKAMRRMVISNFLTsGQICMIAKRVYVHqsIYKSFVEKYREAADKWirvGDPFNpkvTVGPVNNPGQVKYVKS 346 Bacillus sp. NR...
AAF75990     255 DDv-dLSPETMRQIVKGAFGTtGQVCFGLKRIYVPtrIHDRFVEAFSAAVDEIv-vGPGDDprvTMGPLNNAQQKNLVEK 332 Mycobacterium v...
YP_511731    287 EDa-aLDDGAFMRMYMGAFMSsGQICMALKRLYVHrsRFDEVVDGLEATCNRMv-vGDGLLdgtNMGPVNNAKQLQVVTD 364 Jannaschia sp. ...
EDZ44744     251 PDv--DVKAAAEKVYGGAFLNaGQVCLAVKRAYVHsdIYEAFCSELAALAEQAv-vDDGMKqgtTIGPIQNKAQFDKIKG 327 Rhodobacterales...
YP_001262562 253 DDv--DTKTVARKVFDGAMRNaGQVCIATKRAYVPeaIYDDFCDELGRLARETv-vDDGTRqgaQIGPVQNRQQYEKLTA 329 Sphingomonas wi...
YP_295673    253 DDa--NVDDIAPKIFGSAFYNcGQVCLALKRLYVHasIHNQLCEALAELARQAv-vGNGADegvTIGPLQNAMQYDKAGR 329 Ralstonia eutro...
CAJ88625     259 PGa--DVDAVAGDLFARAMTNsGQFCAAVKRVYVHrtQYHRLAAAMADLASAAv-mGDGLDpatEYGPLVNRAQRDRVAG 335 Streptomyces am...
YP_001507606 251 DDv--DPAAIVRKLFEGAFDNsGQVCSGIKRLYVPesLHDVVVDALAAQAAAAr-vGDGMDpdtQVGPIQNRPQYERVCD 327 Frankia sp. EAN...
EDY80708     247 ADc--DPKTIANNLLDSAWRNaGQVCSAIKRVYVHesIYQKLLVALSEQIPNYi-vGNGLTegvRIGPLTTESSLRRANG 323 Verrucomicrobia...
Feature 1                                                                                        
AAD23400     326 VTEQaladGARAAWGGHRld----gpGYFFAPTILTDvlpgsPVVTEEQFGPVLPVLPYRsLDEAVDAANSTGFGLGGSV 401 Streptomyces au...
ZP_01169854  347 LVEDarskGAEVIQLGKIldpdlmdnGYFLQPTLVLGadphdPIVVEEQFGPTVPIIPYDdEEQVIQLHNESIYGLTSSV 426 Bacillus sp. NR...
AAF75990     333 IVDDarssGATVTTLGQRldsaawdhGHFMMPSVVTAadprlAIVEEEQFGPVVPVLKYDeLDDVIRLVNQSQYGLAASI 412 Mycobacterium v...
YP_511731    365 MINEarhsGTDVRELGQVpdealyatGYFQRPTLVVDpdpslKIVAEEQFGPALPILPFDtEDEAIAAANDSRFGLCSSV 444 Jannaschia sp. ...
EDZ44744     328 FLEDar-aCGKIIAGGTPkd----gpGYFVPPTIVRDvtdgqKIVDEEQFGPVLPVIRFDdIDDVIARANASDYGLGGSV 402 Rhodobacterales...
YP_001262562 330 LIADaa-qSGTIVAGGEPmd----gpGYFIRPTIVRDiaedtPLVREEQFGPVLPVLKYSdIDELLERVNDTEYGLGGTI 404 Sphingomonas wi...
YP_295673    330 FLAAar-hDGKILAGGALln----gdGYFVAPTIVRDlhdqsELVAQEQFAPILPVLRYDaIDEAVVRANASPYGLGGSV 404 Ralstonia eutro...
CAJ88625     336 MVDEavryGARVLAGGRVpd----rpGHFYPPTVVTDlpagtRLEEEEQFGPVVPVVPYDdPQEAIARADASPYGLGCSL 411 Streptomyces am...
YP_001507606 328 LVAEalagGATAAAGGAPid----gpGYFFPPTVLVGaaegtRIVDEEQFGPVLPVLPYRdIDEAVARANATNYGLSGSV 403 Frankia sp. EAN...
EDY80708     324 ILESvsrsGAKSLRNSQSkq----dsGFFVAPSIVYDidplhPLVLEEQFAPILPIISYQtIDQAIEWSNQTNYGLSASV 399 Verrucomicrobia...
Feature 1                                                                        
AAD23400     402 WGtDLDQAETVADRLECGTAWINHHa--eLSLAQPFAGVKDSGVGVAGGPWGLYGNLRPFVVHR 463 Streptomyces aureofaciens
ZP_01169854  427 WG-DEEEAIKVARRIEAGTTMINTAavqgLDVRFPFGGVKQSGVGREYGKEGLKSYLEVHVINI 489 Bacillus sp. NRRL B-14911
AAF75990     413 WTsDEERAFLLGRRFDTGSVFINSHtftsLDPRAPFGGAKASGLGREFSPASLDSYTELQTISR 476 Mycobacterium vanbaalenii PYR-1
YP_511731    445 WTeDRDRAVALSRRIEAGYTYLNAHgpaaQDGRGPFGGFKDSGIGRNLGYEGVIQFQGHHTISG 508 Jannaschia sp. CCS1
EDZ44744     403 HSgDTAKATEIAGRIESGTIWVNQQl--nIGPHIPMAGFKGSGLGVEQSVEGLAEYTQMQVINV 464 Rhodobacterales bacterium Y4I
YP_001262562 405 WAsDVDRASELALRVRTGTVWVNRPq--gVDPRVPFRGAKQSGIGTEMGEAGFEEYTQGQVVSV 466 Sphingomonas wittichii RW1
YP_295673    405 WSaDEDRARAVAQRLQVGTAWVNHHl--hFGPHIPLVGAKESGVGVEFGTEGLAEYAQLSVINI 466 Ralstonia eutropha JMP134
CAJ88625     412 WG-DEGRARALADRPQCGTVWINTHg--dLRHDVPFGGHRDSGIGVEYGPWGLHEYTQLKVRHI 472 Streptomyces ambofaciens ATCC 2...
YP_001507606 404 WSaDPDRAGAVAERLDCGTAWVNAHv--aLGPHQPFGGLKWSGVGVENGPWGLAGYTDLQVQYR 465 Frankia sp. EAN1pec
EDY80708     400 WTsNPSIGYEIAAQIECGRVGINGHr--rAKPSAPFGGFKHSGIGRELGIWGLSEMCETQVVNI 461 Verrucomicrobiae bacterium DG1235

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