Conserved Protein Domain Family
STAS_SulP_like_sulfate_transporter

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cd07042: STAS_SulP_like_sulfate_transporter 
Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
The SulP family is a large and diverse family of anion transporters, with members from eubacteria, plants, fungi, and mammals. They contain 10 to 14 transmembrane helices which form the catalytic core of the protein and a C-terminal extension, the STAS (Sulphate Transporter and AntiSigma factor antagonist) domain which plays a role in the function and regulation of the transport activity. The STAS domain is found in the C-terminal region of sulphate transporters and bacterial anti-sigma factor antagonists. It has been suggested that this domain may have a general NTP binding function.
Statistics
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PSSM-Id: 132913
View PSSM: cd07042
Aligned: 447 rows
Threshold Bit Score: 49.9326
Threshold Setting Gi: 27379046
Created: 16-Oct-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P50443       569 YKNLQTKPGIKIFRFVAPLYYINKECFKSALYKQTVnpilikvawkkaakrkikekvvtlggiqdemsvqlshdplelhT 648 human
NP_956061    453 PKVKVSDHGVIVLEIDNGLNFTSTEHLSRLVYKHALhas-------------------------------------pprS 495 zebrafish
XP_789420    490 QQLQVGAESVAVVTVDSSIRYPSIDYISEQITELSSsvd-------------------------------------hptK 532 purple urchin
BAE75799     463 PQIKVSDHGVLLMELASGLSFPATEHLSRIIHTEALqaa-------------------------------------sprS 505 mefugu
XP_780092    475 LTSKEVDQSVVIIQMERGLRFPAVSELQNLLDDKALiqe-------------------------------------kppS 517 purple urchin
XP_001842365 477 TILLDSSCHTLLVRPASDLTFSSAEYLRDRITRAVAeaye-----------------------------------apidV 521 southern house ...
Q86WA9       471 PETKVSEGPVLVLQPASGLSFPAMEALREEILSRALevs-------------------------------------pprC 513 human
XP_969859    458 EIRDNQGNQYIYIKPEVGLYYAATDYLTTNVIEAYNnrr--------------------------------------nlP 499 red flour beetle
BAG55918     482 EVIKTNCGNYVLLKVQGNLNYPGVEHVNTETQKASQtdp-------------------------------------hppA 524 purple tipped a...
XP_002116719 497 PRIEMFADEVYVLKINGNLNYPGVERFINYIQNKIFgrkg-----------------------------------atrkC 541 Trichoplax adha...
P50443       649 IVIDCSAIQFLDTAGIHTLKEVRRDYEaigIQVLLAQCNpTVRDSLTNGEYckkEEENLLFYSV 712 human
NP_956061    496 LVLDCSQISSIDFTVIHELTDLLKQFQirgAALIFTGLKpSVLQVLLLADLpafRHTDTVDEAL 559 zebrafish
XP_789420    533 LVLDFSRVNMIDYTVVQGMSDLMVDLRragVKAAFANVLpSIKEQLNKGDIyqlRMFDSVQDAI 596 purple urchin
BAE75799     506 VVLDCHHVSTIDYSVISELKDLLRQFKlreVELVFCRLQpSVLQVLLAADLqglRSTDSLEAAL 569 mefugu
XP_780092    518 AILDFSNVSSMDYSVIEGLKDIFKSFSkknSTLVLAGVRpSMRTLIDKAKIkdvVIYDTVDDAL 581 purple urchin
XP_001842365 522 VVLDGAGVNFVDTTVAKNLLCVETDLRakeVGLVLWRWSrATAGALVRLDRnflPLLRDDKELG 585 southern house mosquito
Q86WA9       514 LVLECTHVCSIDYTVVLGLGELLQDFQkqgVALAFVGLQvPVLRVLLSADLkgfQYFSTLEEAE 577 human
XP_969859    500 IVLDCSNIIRVDYAACQTIDNLVKTFNktnKKVTLMNVKpHIFNIWRQTIDfdhLKVCQSVDNI 563 red flour beetle
BAG55918     525 IVVDLSVVTSIDFSVTQALLTVLEEMKnesILVFFFGVQdDVRNMMIRSGIdseIINQGEQRVI 588 purple tipped acropora
XP_002116719 542 VVIDCSHIFMIDYTTTQGFNQILEEFKrfdSKLHFAEVHpRIRRTLIAAGVddgIIFPTVDAAT 605 Trichoplax adhaerens
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