2VY9


Conserved Protein Domain Family
STAS_RsbR_RsbS_like

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cd07041: STAS_RsbR_RsbS_like 
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Sulphate Transporter and Anti-Sigma factor antagonist domain of the "stressosome" complex proteins RsbS and RsbR, regulators of the bacterial stress activated alternative sigma factor sigma-B by phosphorylation
The STAS (Sulphate Transporter and Anti-Sigma factor antagonist) domain of proteins related to RsbS and RsbR which are part of the "stressosome" complex that plays an important role in the regulation of the bacterial stress activated alternative sigma factor sigma-B. During stress conditions RsbS and RsbR are phosphorylated which leads to the release of RsbT, an activator of of the RsbU phosphatase, which in turn activates RsbV which leads to the release and activation of sigma factor B. RsbS is a single domain protein (STAS domain), while RsbR-like proteins have a well-conserved C-terminal STATS domain and a variable N-terminal domain. The STAS domain is also found in the C- terminal region of sulphate transporters and anti-anti-sigma factors.
Statistics
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PSSM-Id: 132912
View PSSM: cd07041
Aligned: 154 rows
Threshold Bit Score: 65.1648
Threshold Setting Gi: 149921384
Created: 16-Oct-2008
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2VY9_A        4 RVPILKVd-dYWVVAIEETLHDQSVIQFKEELLHNITgvagkGLVIDISAL-EVVDsfVTRVLIEISRLAELLGLPFVLT 81  Moorella thermoa...
NP_936637     6 SAISISKlqdVLIASVQVDLTESTLRDFSLDLLDAVKstrakGVMIELSGV-KTLDgeSMHRLLDVVKTVEVMGCRCLLV 84  Vibrio vulnificu...
ZP_01171615 219 SSPLIPVidgITVLPLMGKFEENRSSQLIEKVLSGLLlhkpsTLIVDITGI-NSVDdyILELINNLTKTTTLMGVKPFIV 297 Bacillus sp. NRR...
ZP_03225960 138 STPILKLwdgILVFPIVGSLNEERSKKLVEVALNRIIkdraeHILLDLSSL-NTMDevSIHYLYQLVDTIRLVGSEAYLV 216 Bacillus coahuil...
ZP_01169171 139 SVPMITIwdcTLALPLIGGYDKERSDYVLGRLLEKCVkdkikYVLIDLSGL-YDFQeeTKFELQKLYDCLRLIGTECLLV 217 Bacillus sp. NRR...
ZP_01170631 136 SSPFIHIsdeLVLIPLFGELSEQLINQNKDRLLDMLHdsnvnRILIDFNGV-GSISrdGLIFFQQLLSQFSLLGAESVLI 214 Bacillus sp. NRR...
ZP_01859099 139 SVPIIKVwdrTIALPLIGHFDNDRAERMITAVLHECAsnkieYVLVDLSGI-YELDmnIKYHIQNLCDCLSLIGSQCVIA 217 Bacillus sp. SG-1
ZP_01859046 222 SSPIIPVlegVVVVPLLGKYDENRSEDLITKTLNNLPkhkadYLVIDLTGLhQYISqfTVELLSKLASAASLIGTETILV 301 Bacillus sp. SG-1
ZP_01858508 216 SSPIIPVmdsILVVPLIGRYDELRAEELLDRTLLNLPrykatHLIADLTSL-KGVNdyTLDFIDKFVKATSILGTKCILV 294 Bacillus sp. SG-1
ZP_01170010 218 STPIIPVlkgIVVVPLIGNFNDERLSNFIERSLLEFSrlkanYLLIDLTGV-KGLDsyTIEGIQKLILSIRLIGGECFIV 296 Bacillus sp. NRR...
2VY9_A       82 GIKpAVAITLTEXGLdl-rgXATALNLQKGL 111 Moorella thermoacetica
NP_936637    85 GLRpGVVIGLMDIGIdl-asTLCVADLEQGF 114 Vibrio vulnificus YJ016
ZP_01171615 298 GISpQISIQLTERNItl-ndQHCFATLKHAI 327 Bacillus sp. NRRL B-14911
ZP_03225960 217 GITpELTLSLINKGYkwktfMEAGQALLHII 247 Bacillus coahuilensis m4-4
ZP_01169171 218 GMTaELARTAGDIHPsiqsfRSAHEGLKYLI 248 Bacillus sp. NRRL B-14911
ZP_01170631 215 GISpEQAKFIHNNFPgl--eAKYINSLHKAI 243 Bacillus sp. NRRL B-14911
ZP_01859099 218 GITpEFAKAAGELSGknlifSNAHAGLKYVI 248 Bacillus sp. SG-1
ZP_01859046 302 GISpKLAQEITGTDMql-srFSCFSTLKHGI 331 Bacillus sp. SG-1
ZP_01858508 295 GISsELSIQITQRGHri-dkVPCLSTLQKGV 324 Bacillus sp. SG-1
ZP_01170010 297 GISaDQAIQISHSNIlf-skVQTFSTLQHGV 326 Bacillus sp. NRRL B-14911
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