Conserved Protein Domain Family
cupin_YbfI-like_N

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cd07001: cupin_YbfI-like_N 
AraC/XylS family transcriptional regulators similar to Bacillus subtilis YbfI, N-terminal cupin domain
This family contains bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators, including YbfI, an uncharacterized Bacillus subtilis. In Pseudomonas putida, this protein is thought to regulate the expression of phenylserine aldolase. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.
Statistics
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PSSM-Id: 380405
Aligned: 9 rows
Threshold Bit Score: 98.2313
Created: 4-Dec-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
metal binding
Feature 1: metal binding site [ion binding site], 4 residue positions
Conserved feature residue pattern:H H E HClick to see conserved feature residue pattern help
Evidence:
  • Comment:The four-coordinate metallocenter includes three histidines and one glutamate.
  • Citation:PMID 8612079

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                          # #   #                                 #                  
O31449        15 HIEAYRFKGIMQK--FPNHFHDYYVIGFIEkGQRYLACqdQEYIInPGDLLLFNPrDTHSCEQidgrtLDYRCINVM 89  Bacillus subtilis ...
NP_865637     18 DGITVHQWESVDHt-WPNHSHPEYKLGVSEgGTGTFFNrgQRYFTgPGKLLVIHPnEVHSCTAtgawrYLYAAPNVV 93  Rhodopirellula bal...
NP_347961     18 DYEIYHYSNNDIRs-VSIHHHDFYEFYFFIsGDVTYLIegKSYCLnSGNIILINSrELHQAIIns-qrENYERIVLW 92  Clostridium acetob...
NP_349422     11 DFQLFHLKDRKSQs-FEFHYHDFNKIIIFIsGKVTYLIegKAYELkPWDILLVNNhDVHKPIIds--sKVYERIIIW 84  Clostridium acetob...
NP_814222     19 QYEIFHVKDMVSPekTIYHYHDFYEVHCTLkGVATFFLdgHQFDVeAGTVLLIHYhDLHRIIKqs--tDDFERMYIF 93  Enterococcus faeca...
YP_001087787  15 KIEAYRFKGIMQK--FPNHFHEHYVIGFIEkGQRYLSCknKEYTTsTGDLLLFNPfDSHTCEQiddkvLDYRCINIK 89  Clostridioides dif...
WP_091751902  15 TVEAYRFQGIMQK--FPNHFHDYYVIGFIEnGRRYLSCknKEYTIePGDLLLFNPrDNHTCEQidgrpLDYRCINVQ 89  Propionispora vibr...
PKL04048      15 KIEAYSFKGIMQK--FPNHFHDYYVIGFIEsGERCLSCknRKYTVePGDLLLFNPrDNHTCEQidgrtLDYRCINVH 89  Synergistetes bact...
WP_104434721  15 NVEAYHFQGIMQK--FPNHFHDYYVIGFIDaGQRYLHCknKDYTVePGDLLLFNPrDNHACAQidgkaFDYRCINIQ 89  Bacteroides xylano...

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