Conserved Protein Domain Family
ChtBD1_GH16

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cd06923: ChtBD1_GH16 
Hevein or Type 1 chitin binding domain subfamily that co-occurs with family 16 glycosyl hydrolases
This subfamily includes Saccharomyces cerevisiae Utr2p, also known as Crh2p, which participates in the cross-linking of chitin to beta(1-3)- and beta(1-6) glucan in the cell wall, and S. cerevisiae Crr1p, a putative transglycosidase which is needed for proper spore wall assembly. ChtBD1 is a lectin domain found in proteins from plants and fungi that bind N-acetylglucosamine, plant endochitinases, wound-induced proteins, and the alpha subunit of Kluyveromyces lactis killer toxin. This domain is involved in the recognition and/or binding of chitin subunits; it typically occurs N-terminal to glycosyl hydrolase domains in chitinases, together with other carbohydrate-binding domains, or by itself in tandem-repeat arrangements.
Statistics
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PSSM-Id: 211314
Aligned: 12 rows
Threshold Bit Score: 99.7476
Created: 20-Nov-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
carbohydrate
Feature 1:carbohydrate binding site [chemical binding site]
Evidence:
  • Comment:based on related proteins with structure
  • Comment:Sequence variations in the binding site can affect binding specificity and binding affinity.
  • Comment:Glycines stabilize the site and may not directly contact the substrate

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                         # ### #   #                    
NP_010874     25 TFCNA-TQACPEDKPCCSQYGECGTGQYCLNNCDVRYSFSHDSCMPVP 71  baker's yeast
XP_455302     30 IGCSL-ENNCPAEWPCCSQFGQCGTGPFCVGGCNPRLSHDPGSCLGQP 76  Kluyveromyces lactis NRRL Y-1140
NP_013314     29 ISCSP-NNPCPAEWPCCSPYNECGAGPICVGGCNVRSSFDEESCAPIP 75  baker's yeast
XP_566898     26 QTCNT-TNLCPSAAPCCSEYGYCGTGSYCLGGCEPLYSHEVTSCRPNP 72  Cryptococcus neoformans var. neoformans JEC21
XP_001824008  23 IKCDA-NNQCPEKYPCCSQYGECGTGAYCLGGCDPMQSFSLDSCMAEP 69  Aspergillus oryzae RIB40
EDK36475      21 IACNE-TSQCPEDAPCCSQYGECGTGAYCLGGCDIRFSYNLSACMPMP 67  Pichia guilliermondii ATCC 6260
XP_445272     26 IYCNA-TSQCPEEFPCCSQFGQCGTGQYCINNCNPKFSFSIDSCVPMP 72  Candida glabrata CBS 138
XP_455839     25 TTCSE-DSHCPEDNPCCNQYGTCGTGSYCLGGCNPKFSYKKEACMPLP 71  Kluyveromyces lactis NRRL Y-1140
XP_001643754  33 IHCSS-DSHCPKEWPCCSQYGECGLGPLCVTNCNPKFSFKQDSCIAMP 79  Vanderwaltozyma polyspora DSM 70294
XP_001832292  23 ATCNE-TSPCPLSSPCCSEYGFCGTGHFCLGGCNPFSSRALDSCKPNP 69  Coprinopsis cinerea okayama7#130
XP_001644186  21 IYCNE-TQACPEELPCCSLTGICGSGTFCLGSCNPKYSFGLDSCLPVP 67  Vanderwaltozyma polyspora DSM 70294
XP_448096     32 VRCSIrDGSCPAEWPCCSPYGVCGSGPTCIGGCNPQYSFREDSCVPSP 79  Candida glabrata CBS 138

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