Conserved Protein Domain Family
PASTA_pknB

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cd06577: PASTA_pknB 
PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis. PknB is a receptor-like transmembrane protein with an extracellular signal sensor domain (containing multiple PASTA domains) and an intracellular, eukaryotic serine/threonine kinase-like domain. The PASTA domain is found at the C-termini of several Penicillin-binding proteins (PBPs) and bacterial serine/threonine kinases. The name PASTA is derived from PBP and Serine/Threonine kinase Associated domain.
Statistics
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PSSM-Id: 119328
View PSSM: cd06577
Aligned: 634 rows
Threshold Bit Score: 34.427
Threshold Setting Gi: 29611820
Created: 3-Sep-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ZP_02042686 465 KVPDVTGKSEADAQKQLEDKGfvva----setDYSDSVPQGYVISTNPTAGTEWae---gNTVTMVVS 525 Ruminococcus gnavus ATCC 29149
ZP_02429150 502 VLGNYVGMDQNKAKEALTKLGfdv-----tikETSSEQAVGTVVEQSLKEGHKVdpdekdRTITLTVS 564 Clostridium ramosum DSM 1402
ZP_02429150 434 VLEDYTGKKEDVAKKALEKLKfev-----eieYEISSKTKGTVIDQSIEKGTKVdptekdRKIILTVS 496 Clostridium ramosum DSM 1402
ZP_03176512 537 MVPDVQYKYLKSAQACLRAGGwkwt----vekVDNNTFGDGTVISQKPEPNKDVdkk-nrPTITLRVS 599 Streptomyces sp. SPB74
Q81ZX8      483 KIPDFTFKNIDSVKKCLQAAGwpyd----pkkVDENTFGEGTVMEQYPAAGDDVdpk-dmPDIVLKIS 545 Streptomyces avermitilis
NP_268044   435 KMKDFVGEKIDEAMATLLKDYgidesqvtqtsVPSDSYPAGTIIKQSPKKGSSFdtk-gsEKITFEVS 501 Lactococcus lactis subsp. la...
ZP_02918446 648 TLPNYVGQKASEAKSALEKLGfsvk---issqLTLDSSQDKKVASQDPVGGTEVrlr-qeDGTPTTVT 711 Bifidobacterium dentium ATCC...
Q9S2C0      487 QVPDFTFKYIGSVKECFNAAGwqmk----vveVDENTYGEGSVRDQFPTAGTDVdpe-nmPEIQLKVS 549 Streptomyces coelicolor
EDX23212    498 TAPDFRYKDILSVKACIQAAGwkyk----vveKDEAVYGQDIVLEQNPAALDKVdk--egTEFTLTVS 559 Streptomyces sp. Mg1
O51090      200 HVKNYVGIYYKDAIASLLSDSinf------diDLANIGDFGNIISQSIPPGTKIne---sDKILITIA 258 Lyme disease spirochete
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