Conserved Protein Domain Family
Glyco_transf_WecG_TagA

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cd06533: Glyco_transf_WecG_TagA 
The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common antigen (eca) synthesis. B. subtilis TagA plays a key role in the Wall Teichoic Acid (WTA) biosynthetic pathway, catalyzing the transfer of N-acetylmannosamine to the C4 hydroxyl of a membrane-anchored N-acetylglucosaminyl diphospholipid to make ManNAc-beta-(1,4)-GlcNAc-pp-undecaprenyl. This is the first committed step in this pathway. Also included in this group is Xanthomonas campestris pv. campestris GumM, a glycosyltransferase participating in the biosynthesis of the exopolysaccharide xanthan.
Statistics
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PSSM-Id: 119439
View PSSM: cd06533
Aligned: 224 rows
Threshold Bit Score: 99.0807
Threshold Setting Gi: 84685615
Created: 8-Jan-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P27620       57 LSSSNFILPDGIGVVMMSRLTNnr----lQSRIAGYDVFKELLGVAnkkkkRIFLYGAKKDVikgvvskissEYPNIKIA 132 Bacillus subtilis
ZP_01013512  53 TSGDDHVVIDGGTTARIVSKLTgvp--ceSLSFDYAGVACAAMDRLaqrgaRLGLIGGTSDEvsrvatflrdRHPGLRVV 130 Rhodobacterales ...
NP_355329    71 LRQADQIHADGMSLVIFSRKFCrq---alRERVATTDLVHAVAKRAeetgsRFYFLGGSEEVnraaveemqrLYPRLVFS 147 Agrobacterium tu...
NP_949917   116 LMEADAIHADGMPLVFVSRFRCgq---slPERVATTDLFHEVAREAskrgaTMYMLGANEESnrravermqrRYPGLRLV 192 Rhodopseudomonas...
ZP_01155365  71 LAAADIVHADGGFLVTLSRHRAgp---aiPERSATTDMIHDFARAFsdgtgSFYLLGGPEEInaacarelrrRYPGLAIA 147 Oceanicola granu...
YP_435807    64 MNNVDLVHADGQSVVTLSRWFSer---piAERSATTDMIHDIPVHYap-tlKHFFLGGLKDVveqaakiysdTYANAEIV 139 Hahella chejuens...
O52500       76 FRGADLINADGQPLVADSKLQSwf---plPERVATTDLFHVVARKAeavgrTFYMFGASEAEnaaavenvrtMYPNLKIV 152 Bradyrhizobium j...
ZP_02969795  56 TSKYDYFIPDGMPLIWCLNRAGag----lKDRVYGPTFMREFLSKVpk-qyTHYLLGGSEECgsrikeifqkLNPGIQFV 130 bacterium Ellin514
YP_750066    67 LLQADLIHADGQSVVTFSKWVKgr---niPERTATTDMIHDIPNYFes-niNHFLLGCENDIvenacklmskRYKNFKIS 142 Shewanella frigi...
YP_832095    60 YEDSDVVLLDGAPVLWLWGRSGeadgpvmDYRLGSTDWIPALGSVEgl--eRIAVIGAGAEAnaravarlagIVPNAKVA 137 Arthrobacter sp....
P27620      133 gy----sDGYVQDRtlv--------akQIARANPDMVFVALGyPHQEKFIHNyrhlf-pkavsIGLGGsFDVFSGNVKRa 199 Bacillus subtilis
ZP_01013512 131 laa-sgyHPSHRQLm-----------sDVAVARPDVLLVSMGsPRQEALALAlkarldhptaiVTCGA-FVHQTARHPYy 197 Rhodobacterales ...
NP_355329   148 gr----rNGYFSRAeeda------vlaDITTSKTDILWVGFGiPLEQRFVSRnldrlsgiaviKTCGGlFDFLAGRNSRa 217 Agrobacterium tu...
NP_949917   193 gh----rHGYFANEaeei-----avcrEIGALAPDILWVSMGvPREQAFVVRnrhrlttvgviKTSGGlFDFLSGSKPRa 263 Rhodopseudomonas...
ZP_01155365 148 gr----rHGFFGHEdehg------iidHINRSGADIVWIGLGkPREQAIARRwrdrl-tarwvITCGGcFNYVTGHYRRa 216 Oceanicola granu...
YP_435807   140 gv----rDGYFSAAdeln------iveEINQSGADVLWVGLGkPKEQEFCIRhkdkl-kvpvvISCGGcYNFLTGHYKRa 208 Hahella chejuens...
O52500      153 gh----sHGYLRGEslra------kveEINALAPDYLWVALGvPNEQAFVEQytplltnvgviKTSGGlFNFLSDSRSRa 222 Bradyrhizobium j...
ZP_02969795 131 ga----fHGRCGLDgildgnseqmvmaDLARLSPDFIWVGFGtPKQQAWTRKhkqli-rrgviLTVGFaFDVNAGMKPDa 205 bacterium Ellin514
YP_750066   143 gf----nDGFFSIEeede------iidKINSSRVDVLWVGLGkPKEQEFCIRnkekl-nvsviITCGGcYNYITNDYPRa 211 Shewanella frigi...
YP_832095   138 gmpgegwNSALEGEav----------aWLQELRPQMVLLGLGmPLQEMVLRRrlsvl-ppavyCAVGGaIEQIAGIQKLa 206 Arthrobacter sp....
P27620      200 PSWMirlNLEWFYRLILNPWR-WKRM 224 Bacillus subtilis
ZP_01013512 198 PEVYtrrNLRWLYRALNTPHI-APRI 222 Rhodobacterales bacterium HTCC2654
NP_355329   218 PQWMqdmGLEWLYRAMLEPKRlGKRY 243 Agrobacterium tumefaciens str. C58
NP_949917   264 PQWMqkvGLEWLWRMALEPRRlGVRY 289 Rhodopseudomonas palustris CGA009
ZP_01155365 217 PGWMqraNLEWLHRLCTDPRRlARRY 242 Oceanicola granulosus HTCC2516
YP_435807   209 PEWVqnnGLEWVHRMVLNPRKlFWRY 234 Hahella chejuensis KCTC 2396
O52500      223 PQWMqkfGLEWAWRTWLEPRRlFWRY 248 Bradyrhizobium japonicum
ZP_02969795 206 PIWMqrlGLTWVFRLLSEPKRlASRY 231 bacterium Ellin514
YP_750066   212 PVWMqkiGFEWLHRMSTNPRKlFYRY 237 Shewanella frigidimarina NCIMB 400
YP_832095   207 PRWLgrlGLEWAWRLMLHPRRvAYRV 232 Arthrobacter sp. FB24
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