Conserved Protein Domain Family
ACD_LpsHSP_like

?
cd06471: ACD_LpsHSP_like 
Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and protect against cell stress, and are generally active as large oligomers consisting of multiple subunits. Transcription of the genes encoding Lp HSP 18.5, 18.55 and 19.3 is regulated by a variety of stresses including heat, cold and ethanol. Early growing L. plantarum cells contain elevated levels of these mRNAs which rapidly fall of as the cells enter stationary phase. Also belonging to this group is Bifidobacterium breve (Bb) HSP20 and Oenococcus oenis (syn. Leuconostoc oenos) (Oo) HSP18. Transcription of the gene encoding BbHSP20 is strongly induced following heat or osmotic shock, and that of the gene encoding OoHSP18 following heat, ethanol or acid shock. OoHSP18 is peripherally associated with the cytoplasmic membrane.
Statistics
?
PSSM-Id: 107228
View PSSM: cd06471
Aligned: 53 rows
Threshold Bit Score: 103.327
Threshold Setting Gi: 89210444
Created: 14-Jul-2008
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
putative dimer
Feature 1:putative dimer interface [polypeptide binding site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1           #####      # # ##                                                 #          
YP_001180832  44 MRTDIKETENEYIIEAELPGVKKEDIKIELYDNKLTIKAEtk-----qEEKEer-enFIRRERRYGAFSRTFYLDNVKED 117 Caldicellulosir...
NP_786069     37 MKTDVVEHDDDYTVTAELPGFDKDAITVKYADEWLTIRAHrs----qdDRNDdg--rVLHRERMDADFTRKFHLTNVVRE 110 Lactobacillus p...
CAA96463      18 LQSDVAEDEHEYTVKIDVPGMSKDDIHLSYTDGILTISAHrst---fkDDSDkk-knLLRQERSEGSVSRSFSLPNVDKK 93  Lactobacillus d...
YP_001039513  46 IKVDIRENDKEYILEADIPGVDKENITVEVNGDVLTISAKw------dEQTEikkenYLRRERRASSMSRSFTLENVDSD 119 Clostridium the...
YP_794314     36 MKTDVVEHDKDYVVTAELPGFKKDDIHVDYHDETLRISGKtevnqsakDDDGr----ILRQERRSQNVARSFYLPGIDLK 111 Lactobacillus b...
YP_519900     47 MRVDIRENEKEFIVEAELPGVNKEDIQIDCTEDRLTITVQkte--steEQKDn----YIRKERKASSMARSFAIANIRHE 120 Desulfitobacter...
ZP_01274018   37 MKTDVTEDDKNYTVKIDMPGFDKKDIHINYANDILTVTGHrdt---fdDDGDkd-gnVLHSERRYGQMSRQYRLPDVNKK 112 Lactobacillus r...
YP_805106     36 LKTDVSESDTDYKVKIDVPGIDKKDIKLDYQDGVLNVEVKkds---faDHEDek-hnVTMTERSYGIMRRSYELPRVKAE 111 Pediococcus pen...
YP_809933     44 MRTDISENDKEYGLKIELPGLDKKDIKIDYSNDNLTVSGVlss---kaEEKDkk-nnVVRSERRYGNYSRSYYVPGVDEN 119 Oenococcus oeni...
NP_964197     44 MQSDVAETDKDYIVKVDMPGMDKKDIKVSYKDGVLNVSGSrds---fdNLDNnn-gnVLHRERSVGHIQRSYRIPDVDSK 119 Lactobacillus j...
Feature 1                ##       
YP_001180832 118 gIKAKYEDGILRIVLPK 134 Caldicellulosiruptor saccharolyticus DSM 8903
NP_786069    111 eIQAHYQAGLLTVTLPK 127 Lactobacillus plantarum WCFS1
CAA96463      94 gISAKLDGGVLTVTLPK 110 Lactobacillus delbrueckii
YP_001039513 120 rITAKHENGVLTLILPK 136 Clostridium thermocellum ATCC 27405
YP_794314    112 nVKATYADGILTLTLPK 128 Lactobacillus brevis ATCC 367
YP_519900    121 eITAKYENGLLTVTLPK 137 Desulfitobacterium hafniense Y51
ZP_01274018  113 dIKAQYKNGVLTITLPK 129 Lactobacillus reuteri 100-23
YP_805106    112 dIKAKVDNGVLSITLPK 128 Pediococcus pentosaceus ATCC 25745
YP_809933    120 kISAKYENGILNLTLPK 136 Oenococcus oeni PSU-1
NP_964197    120 eISAKDVNGVLTITLPK 136 Lactobacillus johnsonii NCC 533

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap