1J0A


Conserved Protein Domain Family
ACCD

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cd06449: ACCD 
Click on image for an interactive view with Cn3D
Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia.
Statistics
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PSSM-Id: 107210
View PSSM: cd06449
Aligned: 9 rows
Threshold Bit Score: 392.94
Threshold Setting Gi: 31615397
Created: 9-Jul-2008
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
catalyticpyridoxal
Conserved site include 1 residue -Click on image for an interactive view with Cn3D
Feature 1:catalytic residue [active site]
Evidence:
  • Comment:pyridoxal 5'-phosphate (PLP) forms an internal aldimine bond (Schiff base linkage) with the catalytic residue lysine
  • Structure:1JOA_A; catalytic residue (lys) and cofactor (PLP)
    View structure with Cn3D

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                        #                                            
1J0A_A     22 TPIQYLPNIsrei--gadVYIKRDDLTGlg-iGGNKIRKLEYLLGDALskgaDVVITVGAvhsNHAFVTGLAAkklgLDA 98  Pyrococcus horikoshii
Q9WY68     10 TPVQFLKRLseky--gfnIYVKRDDLTElv-gSGNKIRKLEYLLWEALkkgaTTVFTCGGlqsNHARATAYVSrrygLKP 86  Thermotoga maritim...
Q8XBC7     19 TPLEYLPRFsdyl--greIFIKRDDVTPma-mGGNKLRKLEFLAADALregaDTLITAGAiqsNHVRQTAAVAaklgLHC 95  Escherichia coli O...
Q0K1H0     16 TPIHPLSRLseslggkveLYAKRDDCNSglafGGNKTRKLEYVIPDVLaqgaDTLVSIGGiqsNHTRQVAAIAahlgLKC 95  Ralstonia eutropha...
Q98AM7     15 TPIEKLDRLgkhlggkveIYAKREDCNSglafGGNKLRKLEYVIPDAIasdaDTLVTVGGvqsNHTRMVAAVAakigMKC 94  Mesorhizobium loti...
Q9URX3     16 TPITSMKRLsktlggkveIFAKREDCNSglafGGNKIRKLEYLIPEAIdggyDTLVSIGGiqsNQTRQVAAVAahlgLDC 95  fission yeast
Q4ZVH4     16 SPITPLKRLsehlggkveLYAKREDCNSglafGGNKTRKLEYLVPEAIdggyDTLVSIGGiqsNQTRQVAAVAahlgMKC 95  Pseudomonas syring...
Q5KMX3     23 SPISYLPNLtavlggkvkLYAKREDCNSglayGGNKVRKLEYLVADAKakgcNTLVSVGGvqsNHTRAVTAVAvasgLKA 102 Cryptococcus neofo...
Q7M523     16 SPISNLNRLsqhlgskvnVYAKREDCNSglafGGNKLRKLEYIVPDIVegdyTHLVSIGGrqsNQTRMVAALAaklgKKC 95  Williopsis saturnus
Feature 1                                                                                     
1J0A_A     99 ILVLRgke----------elkGNYLLDKIMgiETRVYdakdsfeLMKYAEEIAeelkreGRKPYVIPPGga-sPIGTLGY 167 Pyrococcus horikoshii
Q9WY68     87 VLFLRkgek---------vlnGNLLLDILLgaEIVEVspeeyerIDEIFDVHKkmrekkGEKVYVIPEGgs-nSLGAFGY 156 Thermotoga maritim...
Q8XBC7     96 VALLEnpigtta---enyltnGNRLLLDLFntQIEMCdal--tdPNAQLEELAtrveaqGFRPYVIPVGgs-nALGALGY 169 Escherichia coli O...
Q0K1H0     96 VLVQEnwvnysd---avydrvGNIQMSRIMgaDVRLVsegfdigIRPSWEEAMesvrkaGGKPYPIPAGcsehPLGGLGY 172 Ralstonia eutropha...
Q98AM7     95 LLVHEswvphed---vvydrvGNILLSRILgaEVRLVddgfdigIRRSWEKALyevkarGGRPYAIPAGasvhPNGGLGY 171 Mesorhizobium loti...
Q9URX3     96 VLIQEdwvdykd---tmydrvGNIELSRIVnaDVRLDsskfdigIRPSFKNALeeltkkGKKPFPIPAGcsehPYGGLGF 172 fission yeast
Q4ZVH4     96 VLVQEnwvnysd---alydrvGNIEMSRIMgaDVRLDsagfdigIRPSWEKAMadveesGGKPFPIPAGcsehPYGGLGF 172 Pseudomonas syring...
Q5KMX3    103 VTVQEkwvpidp---plysetGNILLSRLMggDVRLNqetfdirHKKATEDAFkdveakGGKPYYIPAGasdhPLGGLGF 179 Cryptococcus neofo...
Q7M523     96 VLIQEdwvpipeaekdvynrvGNIELSRIMgaDVRVIedgfdigMRKSFANALqeledaGHKPYPIPAGcsehKYGGLGF 175 Williopsis saturnus
Feature 1                                                                                     
1J0A_A    168 VRAVGEIATQSev---kfDSIVVAAGSGGTLAGLSLGLSIlnediRPVGIAVgrfgevmtskldnli----keaaellgv 240 Pyrococcus horikoshii
Q9WY68    157 FNAVLEMKDQLnle--sfDAIVCAVGSGGTIAGLSAGISFleyhvPVVGVNVttknsdyfvgkvkrii--sgmeeyglrv 232 Thermotoga maritim...
Q8XBC7    170 VESALEIAQQCega-vniSSVVVASGSAGTHAGLAVGLEHlmpesELIGVTVsrsvadqlpkvvnlqq---aiakelelt 245 Escherichia coli O...
Q0K1H0    173 VGFAEEVREQEaglgfrfDYIVVCSVTGSTQAGMVVGFAAdgradRVIGIDAsakpeptraqilriarhtaelvglgrdi 252 Ralstonia eutropha...
Q98AM7    172 VGFAEEVRAQEeqlgfafDYMVVCTVTGSTHAGMLVGFAKdgrqrNVIGIDAsatpaktkaqvlsiarhtatlvelgsel 251 Mesorhizobium loti...
Q9URX3    173 VGCVEEIYEQEkqlgfkfDKIVVCTVTGSSFAGIIVGMALtgrqkDVIGIDAsatpektkaqvlriaqntakliglekel 252 fission yeast
Q4ZVH4    173 VRFADEVRQQEeelgfkfDYIVVCSVTGSTHAGMLVGFAAdgraqRVIGIDAsakpektraqvlriaqntaklvelgrei 252 Pseudomonas syring...
Q5KMX3    180 TNWVVELAKQEkelgvffDVVIVCSVTGSSHAGTVVGAVAegrkrKIIGIDAsgkpeatrnqvlkiarntaallderlei 259 Cryptococcus neofo...
Q7M523    176 VGFADEVINQEvelgikfDKIVVCCVTGSTTAGILAGMAQygrqdDVIAIDAsftsektkeqtlrian--ntakligveh 253 Williopsis saturnus
Feature 1                                                                             
1J0A_A    241 kvevrpELYDYSFGeygkitGEVAQIIRKVGtreGIILDPVYTGKAFYGLVDLarkg--elgeKILFIHTGG 310 Pyrococcus horikoshii
Q9WY68    233 netvfeVVDDYRGPgyaipsSEDVEILKEVAsieGIILDPVYTAKAFRGMIEMfrn----sekNVLFIHTGG 300 Thermotoga maritima MSB8
Q8XBC7    246 asveilLWDDYFAPgygvpnDEGMEAVKLLArleGILLDPVYTGKAMAGLIDGisqkrfkdegPILFIHTGG 317 Escherichia coli O157:H7 s...
Q0K1H0    253 teadvvLDTRYGGPeyglpsAGTLEAIRLSArleGMMTDPVYEGKSMQGMIDMvrrgefpqgsKVLFAHLGG 324 Ralstonia eutropha H16
Q98AM7    252 aeddvvLLEDYAHPrygipsEETKEAIRLCArleGMITDPVYEGKSMQGMIDLvqkgffpagsRILYAHLGG 323 Mesorhizobium loti MAFF303099
Q9URX3    253 tesdvnIDTRFAHPaygipnEGTIEAIKLCGateGVLTDPVYEGKSMQGLIHLvrnneiaegsKVLYIHLGG 324 fission yeast
Q4ZVH4    253 taedvvLDTRYAYPeyglpnDGTLEAIRLCArleGVLTDPVYEGKSMHGMIDMvrngefpegsKVLYAHLGG 324 Pseudomonas syringae pv. s...
Q5KMX3    260 keedviLDDRFHAGiygipdDETIAAMKLAAqtdAFITDPVYEGKSMAGMIRLvkegaikegsNVLYIHLGG 331 Cryptococcus neoformans va...
Q7M523    254 efkdftLDTRFAYPcygvpnEGTIEAIRTCAeqeGVLTDPVYEGKSMQGLIALikedyfkpgaNVLYVHLGG 325 Williopsis saturnus

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