Conserved Protein Domain Family
CESA_like_1

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cd06439: CESA_like_1 
CESA_like_1 is a member of the cellulose synthase (CESA) superfamily.
This is a subfamily of cellulose synthase (CESA) superfamily. CESA superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members of the superfamily include cellulose synthase catalytic subunit, chitin synthase, glucan biosynthesis protein and other families of CESA-like proteins.
Statistics
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PSSM-Id: 133061
View PSSM: cd06439
Aligned: 44 rows
Threshold Bit Score: 259.437
Threshold Setting Gi: 119872949
Created: 11-Dec-2007
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
DXD motif
Feature 1:DXD motif
Evidence:
  • Comment:DXD motif in the catalytic site could be in binding the metal ion that is used to corordinate the phosphates of the NDP-sugar in the active site.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
YP_465020     15 TYAGYPLVlavwdgarealaavrfvsggddrrgrategwptvtLLFSAFDEEAWIRRKIENCLALDYPpdrlEILVGCDG 94  Anaeromyxobacte...
ZP_01305264   22 PFLCYPLIlralptraeq---------------pvaaplpsasLLFCAYNEADAMPEKLANIAMLCQRhpdlECLAFDDG 86  Sphingomonas sp...
CAO81406      18 HFVGYGLFlfiitslfkkaki----------sipapdvypsitVICSAYNEEKVIEEKIRSFLQLNYPkdriKMIIISDD 87  Candidatus Cloa...
YP_001038736  19 AMIGYPVSlkligkcyksrk-----------lekdynhqptvtVMVVAHNEEKVILEKLNNILELDYPqdkiEILVASDN 87  Clostridium the...
ZP_01165717   19 HHLIYPIImlrlsadtgnqte----------slktgneyrtitVLVPAYNEAEYIAAKIRNVASLNYPankiKLVIACDG 88  Neptuniibacter ...
YP_001030102  14 LLAIIPYViylfgvtfgkkpae--------mdmdtkktlpaisIVICAYNEERTIARKIQSISSCTYPnelmEVVLVIDC 85  Methanocorpuscu...
YP_001527542  18 HHAVFPALlralarrrgprpv---------pppvpeadlpvitLVVPAYQEAAFIAAKLKDCAALDYPrdrlKVIVACDG 88  Azorhizobium ca...
YP_566262     18 VYMTYILAaitskpkqyp----------------plkslpkisIVIPAYNEEEVIEDRINNLAEIYPIdk-mEIIVSNDG 80  Methanococcoide...
YP_930956     11 LHFGAPALyllylraapkkp------------lqpaaiypkvaVVVPTYNEAPNIEAKLEDIYSQSYPrdrmSIYVVDSA 78  Pyrobaculum isl...
AAL62778      16 VPLGYYAVakrwlrkdwgi-------------kedggyrpkisVIIPTYNEAEHIAQRLENVAQSYPRdk-lEVVVVDGA 81  Pyrobaculum aer...
Feature 1                                                              ###                       
YP_465020     95 CTDRTAEiarevggs------rvkvhalsPRAGKASVLSRLVPQARG-DLVVLTDANVmle-rgaLRALARRFREPGVGA 166 Anaeromyxobacte...
ZP_01305264   87 SSDGTGDliaaagh--------vtllrgpGRSGKAHGMKQLAARARG-DVLIFTDANVlld-pdaIDRLLARYADPAIGG 156 Sphingomonas sp...
CAO81406      88 STDRTNEivqkytdq------nislviqkPRAGKQNAHNLVLPLLDT-DYVLSTDANSiftpdcvQLLVAKMLSDKRIGL 160 Candidatus Cloa...
YP_001038736  88 STDQTNNivkefikkhp--erkirlyevkARKGKTNAQNEAQKTVTT-EYLVMTDANSmld-rnaVKELMAAFTSDDIAY 163 Clostridium the...
ZP_01165717   89 CTDNTAQlarktaqewqnsdldmkviefkNNHGKIAILNALIPEIQS-EIVALSDASAlis-ndaLLIANQHFKAPRLGI 166 Neptuniibacter ...
YP_001030102  86 SDDKTEEvarselanvd---fswkihineQRSGKNTSLNTGIGLTES-ELVIATDADLvwdnrsvEQLVLRILADDRFAA 161 Methanocorpuscu...
YP_001527542  89 CTDGTPEaaraalaseacaglnaevrdfpVNRGKVAVLNEVIAGLPP-GLVALSDVSAsls-pdaLRRAAAHFADPRIGV 166 Azorhizobium ca...
YP_566262     81 SVDNTEEiarsvlkkh----siegkvlthDRSGVNKAINRGINETSQ-DLVIITGSDGlfdkdtiPNLLGVLLSSDDIGA 155 Methanococcoide...
YP_930956     79 STDGTAEaaerwaagrk--dakvvvlrepERRGKAHALNTALAHLADeEVVVVTDADSrwl--drDTLRKAVAYLAAADA 154 Pyrobaculum isl...
AAL62778      82 STDGTAEiaekwaekag---vdvkvvreeRREGKAKSLNRALGLATG-EVVVIADADAlwa-pdaLRRAVAKLADPSVGA 156 Pyrobaculum aer...
Feature 1                                                                                        
YP_465020    167 VVGRLRLFNptr--reFEESLYWKYETAIKYYEGKHGCVlganGGIYAIRRILFs---pLPPDTIVDDfVIPVRIAARGw 241 Anaeromyxobacte...
ZP_01305264  157 VLGSLHYVGadesataSVGSLYWRLEERLKDEESRTGNVlgadGSIFSIRRSLYp----EFPDSVLDDlTVSMAIVFAGr 232 Sphingomonas sp...
CAO81406     161 VSGEVKMVKrgs--kqSGEAHYWKYEAFLKLMDSRLKTLiganGPIYLIKRELFs----EIPSNSPDDfERVLLTLKRRf 234 Candidatus Cloa...
YP_001038736 164 VCGRLSIVNreasdvsSAEAGYWDSDLATREIEGRIQTItagnGALYACRNSEYh---dFDHIQCHDA-AMPLYYALKGk 239 Clostridium the...
ZP_01165717  167 VAATYKLLNpg----sEGEEKYWNYQINIKRGEAAIGSPigvhGALYLFRKSLFe---tLPSDTINDDfILPMKIVSQGy 239 Neptuniibacter ...
YP_001030102 162 GTGDLQPNPgad-rvtSMEKTYRSYFGRMAEWESAHDATpafnGCLLILRKSIVg---gVNETNGADDaNLAYEAIRKGy 237 Methanocorpuscu...
YP_001527542 167 VAGTYALRAag----sAGEAGYWRYQTAIKADEAALAAPigchGAFYMFRRELWa---pLPPHTINDDvILPMRMVAAGa 239 Azorhizobium ca...
YP_566262    156 VSGDLVPVAkgesifsNSEAAYRSIYGKICTWESNVHSTycfnGPVVAFKKEASs---sLNTRRGADDaSMALSVIKKGy 232 Methanococcoide...
YP_930956    155 VSCLKKPAGg-----gPTEEAYRTWYNRLRLAESLVHSTpvfhGELAAFRREAIag--gFPEDVGADDsYAAIRIAIEGg 227 Pyrobaculum isl...
AAL62778     157 VSCVKRPIGg-----pGIEEGYRGFYNALRVAESKAWSTpifhGELAAFKREALeavggFPTDIGADDsHTATLIALRGl 231 Pyrobaculum aer...
Feature 1                                           
YP_465020    242 evpFEPEAVAFEETTedaghefgRRARIGAGNWQA 276 Anaeromyxobacter dehalogenans 2CP-C
ZP_01305264  233 rliKAKDVIARERLVtargdeyrRKVRIAARAWHT 267 Sphingomonas sp. SKA58
CAO81406     235 iaaYEPQAIIYEEVTekateeisRKVRIITQEWCV 269 Candidatus Cloacamonas acidaminovorans
YP_001038736 240 raiCNHDAVAYEKAGeviedefkRKVRMNRTILMA 274 Clostridium thermocellum ATCC 27405
ZP_01165717  240 kaiYDCNLVALELESatlsmdhkRRVRIASGNFQQ 274 Neptuniibacter caesariensis
YP_001030102 238 rtfYETRAAIYEELPenlkkqytQKVRRAKGLIQT 272 Methanocorpusculum labreanum Z
YP_001527542 240 gavYDRAIVATEEERthraqefrRRVRIASGNVQQ 274 Azorhizobium caulinodans ORS 571
YP_566262    233 rcqYVPSAKFYEYVPdkfheqrrQKIRRATRLLEA 267 Methanococcoides burtonii DSM 6242
YP_930956    228 ravTPPDVWCIEAVPqrg--yarWRLRRAQHLIQT 260 Pyrobaculum islandicum DSM 4184
AAL62778     232 raiVADDVLCVETVPeeg--yhaWRIRRAQHLIQH 264 Pyrobaculum aerophilum str. IM2

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