Conserved Protein Domain Family
GT8_like_2

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cd06430: GT8_like_2 
GT8_like_2 represents a subfamily of GT8 with unknown function.
A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed.
Statistics
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PSSM-Id: 133052
View PSSM: cd06430
Aligned: 7 rows
Threshold Bit Score: 542.826
Threshold Setting Gi: 108872658
Created: 11-Jun-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative ligandmetal binding
Feature 1:putative ligand binding site
Evidence:
  • Comment:annotation is based on homology to other subgroups of the superfamily

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1             ### ##                                                                     
AAH39145      85 MHLAVVACgERLEETMTMLKSAIIFSik--pLQFHIFAEdQLHHSFKGRLDNWsflq--tfnYTLYPITFPsen-aaeWK 159 human
Q5SP46        79 MHLAAVACgERHGEVVNMLKTAVTLSqr--aLRFHIFAEqQLQTSIKADLDSWpafiqgkfsYVLHPISFPheh-heeWS 155 zebrafish
EAT36883      60 IAIVVVACgERHNEALNMIKSAIMFNrnqapLRFIVVAEeQLKQNFVEKLDDWqeindniftYEIHSLTFPean-kdeWK 138 yellow fever mo...
AAH77307      92 MHLAVVACgDRLEETVTMLKSAVLFSfk--kIKFHIFAEdSLKSDFQMKLEIWpqqisrkieYKIYPITFPggn-tqeWK 168 African clawed ...
XP_789869    237 INLSVVCCgDRTNETLVMLKSATVLTqq--lMHFHIFAEdELQAGIAQRLNAWpsvyrrkfaFSLHPISFPpgedpakWK 314 purple urchin
NP_001025907 109 MHLAVVACgERLEETITMLRSAIIFSik--pLHFHIFAEdQLHESFKDILDDFpyeg--kvnYTLYPITFPseg-akeWK 183 chicken
XP_624895     55 VTICVVVCgDRVDEALTMLKSALVFThr--fLQFIILAEtNLIPAFNEKLAEWkllsnktfdFIVKPITFPkgsdaamWK 132 honey bee
Feature 1                 #              # ###                           #                       
AAH39145     160 KLFKPCASQRLFLPLILkevDSLLYVDTDILFLRPVDDIWSLLKKFNSTQIAAMAPEHEEPRIGWYNRFARHPYYGKTGV 239 human
Q5SP46       156 QLFKPCASQRLFLPMILrelDSLLYVDTDVLFLQPVELIWDMLMLFNSTQLIAMAPEHEEPRIAWYSRFSWHPYYGKMGI 235 zebrafish
EAT36883     139 KLFKPCAAQRLFLPSLLphiDSVLYVDSDTIFLSPVQELWSMFRNFNASQFAGMAPEHEDKNAGWYNRFARHPYYGDLGV 218 yellow fever mo...
AAH77307     169 KLFKPCAAQRLFLPMLLqdvDSLLYVDTDVLFLRPLDHVWAFLRRFNDTQLAAMAPEHEISKIGWYSRFARHPFYGTTGV 248 African clawed ...
XP_789869    315 KVFKTCATQRLFLPDLLpnvDSLLYVDTDILFIRPVEEIYSFFKQFNSTQMAALAPEHEAKNIGWYNRFARHPYYGETGM 394 purple urchin
NP_001025907 184 KLFKPCASQRLFLPLILkdvDSLLYVDTDILFLRPVDDIWSFLRKFDSTQIAAMAPEHEEPRIGWYNRFARHPYYGVTGI 263 chicken
XP_624895    133 KLFKPCAAQRLFLPSVLntiDAVLYVDTDTLFLAPPEKIWDEFKKMNSSQLAALSPEHEDPNTGWYNRFAKHPYYGKLGV 212 honey bee
Feature 1        ###                                           ##                        ##      
AAH39145     240 NSGVMLMNMTRMRrkyfkndmttvrLQWGDILMPLLKKYKLNITWGDQDLLNIVFFHNPesLFVFPCQWNYRPDHCIYGS 319 human
Q5SP46       236 NSGVMLMNLTRMRitqfkndmtpvgLHWDELLMPLLQKYKLNITWGDQDLINIIFHYNPemVYTLPCHWNYRPDHCIYGS 315 zebrafish
EAT36883     219 NSGVMLMNLTRMRd-----------FKWEEHIMPIYKEYRLKLVWGDQDIINILFHHHPdmLYIFPCDWNYRADHCMYMS 287 yellow fever mo...
AAH77307     249 NSGVMLMNLTRIRnqhfknnmipagLTWEEMLHPLYQKYKNYITWGDQDLLNIIFYFNPemLYVFPCHWNYRPDHCMYGS 328 African clawed ...
XP_789869    395 NSGVMLMNLTRMRr-----------FGWTQTIVPLYHEYKLKITWGDQDLINILFHDYPqgLFPYACEWNYRPDHCMYSN 463 purple urchin
NP_001025907 264 NSGVMLMNMTRIRrkyfkndmtsvrLRWAEILMPLLKKYKLNITWGDQDLLNIMFFHNPesLYVFPCQWNYRPDHCIYGS 343 chicken
XP_624895    213 NSGVMLMNLTRMRe-----------FRWIEYVIPIHKQYKLKITWGDQDIINIIFHYHPekLYVYSCRYNYRPDHCMYMP 281 honey bee
Feature 1                     # ##  #                                                 
AAH39145     320 NCqeaeeggIFILHGNRgVYHDDKQPAFRAVYEALRNCSFEDDnirsllkpl--elelqktvhTYCGKI 386 human
Q5SP46       316 NCapaedegVFVLHGNRgVFHSDKQPAFRAVYEAFEQYTFGEDlrqsllsrl--evalnetthTYCGKA 382 zebrafish
EAT36883     288 VCdap--dgVKIIHGNRgYFHSFVQPIFNVLYTTIEEYAFRTDihsnfirtv--edsltlpsnSNCDKL 352 yellow fever mosquito
AAH77307     329 NCkaaeeegVSILHGNRgVYHDEKQPAFKAFYEVIRDYTFDDNlfqsmyfpl--qskflesvhTLCGRI 395 African clawed frog
XP_789869    464 NChrtnehgIAVIHGNRgVYHNMKQPAFRAIYESFRDYTFGADlekglieplkhhlsahniekNYCAKA 532 purple urchin
NP_001025907 344 NCkeaeeegIFILHGNRgVYHDDKQPTFRAVYEAIKNYSFGDDlvrsllqpl--elelqktvhTYCGRV 410 chicken
XP_624895    282 VCikaekegALVLHGSRsTFHSEKQPPFKAIYRAMQEYQLGTDpydyllvpm--rnylalehkSNCGKV 348 honey bee

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