Conserved Protein Domain Family
NTP_transferase_like_1

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cd06422: NTP_transferase_like_1 
NTP_transferase_like_1 is a member of the nucleotidyl transferase family.
This is a subfamily of nucleotidyl transferases. Nucleotidyl transferases transfer nucleotides onto phosphosugars. The activated sugars are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. Other subfamilies of nucleotidyl transferases include Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase.
Statistics
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PSSM-Id: 133044
View PSSM: cd06422
Aligned: 65 rows
Threshold Bit Score: 191.245
Threshold Setting Gi: 42521789
Created: 13-Dec-2007
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Substratemetal binding
Feature 1:Substrate binding site
Evidence:
  • Comment:Putative substrate binding site based on conserved residues of similar proteins.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1            ###                                           #                             
NP_274838      2 KAMILAAGRGERMRPLTDTTPKPLLDVAGKPLIGWHLCRLKQagftEIVINHAWlGRQIEDALgdg-saYGVNIAYSPEp 80  Neisseria menin...
YP_375892      2 KAFVLAAGFGTRLRPLTEHLPKPLVPVMNIPGLFYTFALLKQagitEIICNIHHhAEQIRRFIees-rlPGLCITFSEEp 80  Pelodictyon lut...
YP_001529873  11 RALVLAAGFGKRLLPYTRLTPKPLFTIDNRPLLEIVLTRLADagcrGAIVNTHHlHEKIESFLwr--qgYPMPVQTRYEp 88  Desulfococcus o...
YP_630272      2 KAMVLCAGLGTRLRPLTERWPKPAMPFLGQPLLRYHLAVLKAagvtAVGINTHHlPDTMEAVAraecarAGLPLHVVNEp 81  Myxococcus xant...
YP_844665      2 KAMILAAGLGTRLRPLTLARPKVLVPLMGTTVLDFWMWRLRDagacAAVVNAHHlGEKLVSTVae--ntWPIPLESRFEp 79  Syntrophobacter...
YP_066677     10 QAMILAAGFGTRLLPFTAIRPKPLFPILDTPLLILTIRRLQHagfrKIIVNCHHlREQIVQAVq-----GIDGLIIQEEe 84  Desulfotalea ps...
YP_466895      5 AGMVLCAGLGTRLRPLTARVPKPAVPVCGVPLVRYSLALLAGagvrRAVVNVHHlPDAMAAEAgaaaraLGLSLTVSREp 84  Anaeromyxobacte...
ZP_01291382    4 QAMILAAGLGTRLRPHTMVRPKPLFPVLDRPLLRRIIDQLRWagcnSILVNAFHlRQQIKESLa-----DIPGVAVQLEe 78  delta proteobac...
NP_967169      2 NVMLLAAGEGTRLRPYTLTLPKPAIPFVTVPLAGHSLSFLGNlainKLVVNTYHlPGEIHHLFhsl-rhHAKSLHFSDEv 80  Bdellovibrio ba...
YP_001837498   2 NAFVLAAGFGKRMGSLTENTPKPLLKIQSIALLDYALYLLHLwnieKIWVNTHYlGEQIRRHLqn---fKNLQIEVSFEr 78  Leptospira bifl...
Feature 1                                  # #                                                   
NP_274838     81 agGLETAGGIAQALPLLGg-qPFLVVNGDVLTDIDFTaafqtass--lpehisaHLWLVENPPHNPDGDFSLLPdsSVRP 157 Neisseria menin...
YP_375892     81 -sILGTGGGLKRCEPLLKg-gDFLLVNSDIITDIDFRalieqhr----rsqragTLCLYETPEAASIGMVGIEGelVRDF 154 Pelodictyon lut...
YP_001529873  89 -eILGTGGAIANCADFLNs-gPFLVINSDIYTDIDPAdvlrf-------hhghdAPVTLVLHDFPRFNRVWVDEkdRITG 159 Desulfococcus o...
YP_630272     82 -vIQGTGGGIRGLRDFLSd-gDFIVFNGDILYPVDLRpvvalhq----asgalaTMVLQPMPAGETYAAVELDAegRVRR 155 Myxococcus xant...
YP_844665     80 -vLLGTGGGLRNALDFLGt-ePALVINGDIVCDVPLRelprkhs----ehggpvSLLLHDCPRFNNVAVDENDRilGFGS 153 Syntrophobacter...
YP_066677     85 -tILGTGGGLRRALSCLDd-aPLLVTNSDIYHNLDYRslydahl----raclpvTMAMHDCPRFNGVGVLGEEVvgFGAG 158 Desulfotalea ps...
YP_466895     85 -vIAGTGGALREARAALRgadALLLVNGDVLFDVDLGaalaahr----asgalaTMVLLPMPAGARYAAVEVDAggAVRR 159 Anaeromyxobacte...
ZP_01291382   79 -rELGTGGGLRRACAALAp-ePVLVVNGDIVHNLDYQmvyhhhl----atgndvTLVLHDCPRFNNVMVGPGETiaGFAP 152 delta proteobac...
NP_967169     81 gqILGSGGGLGKARDHFMgddSFVMMNADEIILPKESdvmkkailhhrhqrnvaTLMVMDHPDVGTKFGGVWTDahNRVL 160 Bdellovibrio ba...
YP_001837498  79 keILGTAGGIRTALPDDSvfePILLINPDTLLFPNPQftpklgl----akhskiHLYLLPIPEGESYTKISIGKdqTLEF 154 Leptospira bifl...
Feature 1                                                                                       
NP_274838    158 EVNGgng-------ltFSGVGIYRPEMFDGIEAg--sVAKLAPVLRGEMRQNRVSGQK----HTGLWLDVGTVCRLKEA 223 Neisseria mening...
YP_375892    155 AGRRgtgie---ssfiYTGSAVFSPEIFRHLETg--fSSIVETGFYGLVERNTLGYHP----HRGLWQDIGTLESYLRA 224 Pelodictyon lute...
YP_001529873 160 FGENrkaeaagirqlaFTGIHVIDPRIFEFLPPag-aFSNIIEVYDRMISEGVPLQAMt--vSGHTWHDIGTPGDYRQT 235 Desulfococcus ol...
YP_630272    156 IAGHgpggeg-lspwhFTGVHVMSPRVFDFMSPrg-eEDINRGVYVRAMEAGQMVRGVr---VDGYWSDLGTPSRYLAT 229 Myxococcus xanth...
YP_844665    154 EASElkrslpnvrllaFTGIHCIDPSILSVLPPdr-fSDILALYRELIRAGRHPRAIRr---PRVFWREMGSIRAYRDL 228 Syntrophobacter ...
YP_066677    159 SLKNa----------aFSGLHVLDPWVLRDIEEe--sFSCIIDRYKRLLAGGGRISSYr--mDESYWADMGTLADYLDL 223 Desulfotalea psy...
YP_466895    160 IAGRfgpggeglapwhFSGVHVLSAALLDAVPAepfeADVNRHVYPPLMASGAIRGHV----AAGYWNDLGTPERYLEA 234 Anaeromyxobacter...
ZP_01291382  153 SSAAavag----rqlaFTGLQVINPELLLRIPPa--vFYNSIDWYRQLIAAGRRLRALv--vGGHYWTDMGTPADYLQL 223 delta proteobact...
NP_967169    161 GFGKtpiaga-vkawhFVGVQILSDKVFDFIPA----KGESNILYDALTAAIKKGLSVeaypFECTWFETGNPTDFLEA 234 Bdellovibrio bac...
YP_001837498 155 GKGNy----------yYIGLAVLDPICLSSLEKn--qYYDLSDIFKDLAKRGEITGEI----FPGEVLDLGTKELWETY 217 Leptospira bifle...

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