Conserved Protein Domain Family
CESA_CelA_like

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cd06421: CESA_CelA_like 
CESA_CelA_like are involved in the elongation of the glucan chain of cellulose.
Family of proteins related to Agrobacterium tumefaciens CelA and Gluconacetobacter xylinus BscA. These proteins are involved in the elongation of the glucan chain of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues. They are putative catalytic subunit of cellulose synthase, which is a glycosyltransferase using UDP-glucose as the substrate. The catalytic subunit is an integral membrane protein with 6 transmembrane segments and it is postulated that the protein is anchored in the membrane at the N-terminal end.
Statistics
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PSSM-Id: 133043
View PSSM: cd06421
Aligned: 53 rows
Threshold Bit Score: 236.315
Threshold Setting Gi: 145294729
Created: 12-Nov-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
DXD motif
Feature 1:DXD motif
Evidence:
  • Comment:DXD motif in the catalytic site could be in binding the metal ion that is used to corordinate the phosphates of the NDP-sugar in the active site.

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
CAJ50241     155 PSVDVYVPTYNEPLDVVRQTVLAAQALDWPadrlNVYVLDDGRRPefqafceqigi-------------gyltrsdnkhA 221 Bordetella aviu...
ABB23854      85 PAVAILIPARHEPKEVLEQTLLACRNLGYPn--kTIYILDDSSILsykdearelasrf---------nvelfsrdgnrgA 153 Pelodictyon lut...
EDY36717      76 GKVAVVIPVYNEEPWRVVQTAIAAKMAAPT----AVFVLDDSTDEkireeldkyarey---------gfqifrrdkregF 142 Aciduliprofundu...
YP_001507980 148 GTLDVFVTVCGEPVEMVEATLRAALAIDYPh---RTYVLNDGRIAgrpnwrdidalaar-------lgiicftrtdgprG 217 Frankia sp. EAN...
YP_001047613  84 SPVAVFIPVYNEEPDVVEFCVRACAAIAYPd--lRIFLLDDSTDTrkrtamqgicrry---------glrylhrdhrrgF 152 Methanoculleus ...
YP_001615509  99 SVAVFTTAAPGEPLAMFEATLAALARVRYPh---RTYLLDGTADPrfralaerhga-------------vwldsdgvpgA 162 Sorangium cellu...
YP_001001804 111 PELAVVVAAHNEPLWLIEETLTCFYNLTYPn--kRIFLLDDTRYDpseqrsaemakyrqaiedlcqgigvhlfrrpwrgA 188 Halorhodospira ...
NP_627065    162 VAFLTSFVPGKEPLEMVTKTLEAAVRIRHRgl-mHVWLLDEGDDPevkevcarlgvhhfsr--kgvakwnrkkgphrakT 238 Streptomyces co...
YP_715141    142 VAFTTTIVPAKEPLDVVRDTLIAARNIRHDst-iDVWLLDEGDDPavramcaeigvnhfsr--kgverwntgrgrfrakT 218 Frankia alni AC...
BAB54246     112 RVAMVVTKAPSEPFAVVARTLEAMLAQDYPh---DTWLADEDPSEetvrwcdargvlistr--rgredyhrktwprrtrC 186 Mesorhizobium l...
Feature 1                                                ###                                     
CAJ50241     222 KAGNINAALart--------------------qgeYVAIFDCDHVPVRSFLQICMGWFlkdpkLAMLQTPHVFFspdpfe 281 Bordetella aviu...
ABB23854     154 KAGMLNDALahi--------------------nakYIAVFDADQNPMPGFLQKIVPVLeadsrLALVQTPQFYTntees- 212 Pelodictyon lut...
EDY36717     143 KAGAINAWLekyg------------------deydFLTILDADQRPFPSFFKYTLGFFkd-ekVAFVQVPQYYSrvnsm- 202 Aciduliprofundu...
YP_001507980 218 KAANLNHGLart--------------------dgdAIMTLDADHIAVPDLGELVLGYLrd-pkVGFVCTEQRFDvgr--- 273 Frankia sp. EAN...
YP_001047613 153 KAGAINHALshlg------------------gdtpYLLVIDADQRVKPEILADLVPILeadpaVSFIQTPQFFRsephd- 213 Methanoculleus ...
YP_001615509 163 KAGKINAALart--------------------tedFVLVLDPDHLAFPEFLDRVLGHFdd-prVGFVQVSQGYYnqads- 220 Sorangium cellu...
YP_001001804 189 KAGMINDFLaflndrapagfeftrspldvepfnieYVAVFDADMNPLPEFAEPLIAQLesepnLAFIQTPQYYSnfetn- 267 Halorhodospira ...
NP_627065    239 KHGNYNAWLdahg------------------ddydFFASVDTDHVPLPNYLERMLGFFrd-pdVGFVIGPQVYGnydnp- 298 Streptomyces co...
YP_715141    219 KHGNHNSWLdahg------------------dtydVVLSVDPDHIPLPNFAERMLGYFrd-pnVAFVVGPQVYGnfrhy- 278 Frankia alni AC...
BAB54246     187 KEGNLAFFYdhygy-----------------erydFVAQMDADHVPTPTYLREILYPFad-paVGYVSAPSICDnnaaes 248 Mesorhizobium l...
Feature 1                                                                                        
CAJ50241     282 rnlgtfrnVPNEGELFYGVVQdgndl-wnatfFCGSCAVIRRTALTAIGGmateSVTEDaltal-------kmnrlGYNT 353 Bordetella aviu...
ABB23854     213 ---rvawsSNIQQAVFYEYISegksv-knamfCCGTNFVMRKDALDSVGGfeegSVTEDvattl-------klhmaGWKS 281 Pelodictyon lut...
EDY36717     203 ----vslsAYIQLIPFLRTIMrarhm-ngsafSLGSGTIYRIKALKEIGGlyekTVTEDiytsl-------llherGYKS 270 Aciduliprofundu...
YP_001507980 274 -----hdvLNNAEPMLYKAVQpakdr-dsaasSCGNGTLYRRTAVESVGGfsewNIVEDlhtsy-------qlhaaGWQS 340 Frankia sp. EAN...
YP_001047613 214 ----pisvTFSYQQHIYNKHVcrglsvnntamLTGSNCIFRVSHLAAIGGmdeaCIAEDiatsf-------tfhlkGRRG 282 Methanoculleus ...
YP_001615509 221 ---piargAAEQTYGFYGPMQlglhg-lgcvvAIGANCTFRRAALASVRGha-vGLAEDlmtsi-------rlhaaGWRS 288 Sorangium cellu...
YP_001001804 268 ---rvaraAGMQQAIFYEYICegkss-qdamfCCGTNVIFRRAALEDVGGfdetSVTEDfatsl-------rfharGWRS 336 Halorhodospira ...
NP_627065    299 ----itkaAESQQFLFHALIQragnr-yggpmFVGTSNAVRIRALKQIGGly-dSITEDmatgfemhrhknpatgrKWRS 372 Streptomyces co...
YP_715141    279 ----ltrgAEAQNYMFHSVIQraanr-faagmFVGTNHAYRVETWRQIGGfq-dSITEDlatsfavhgarnprtnhRWTS 352 Frankia alni AC...
BAB54246     249 ---wsargRLFPEGMFHGPLQsghtg-ggaplCIGSHYAVRTKALKQAGGlg-pELAEDhstsm-------linaaGWRG 316 Mesorhizobium l...
Feature 1                                           
CAJ50241     354 AYLALPQAAGLATEnlsr-higQRTRWARGMAQIL 387 Bordetella avium 197N
ABB23854     282 LYYEHAYVFGMAPEnlgs-yfmQQNRWAMGSAQLF 315 Pelodictyon luteolum DSM 273
EDY36717     271 QYLDLPLVWHGEAPeniraywiQQNRWAYGGFQIL 305 Aciduliprofundum boonei T469
YP_001507980 341 VYHHGPVSVGIAPAtaae-yakQRSRWAMDGLRLL 374 Frankia sp. EAN1pec
YP_001047613 283 VFLDAVYAEGVGPPnlaa-yftQQLRWAYGNTQLL 316 Methanoculleus marisnigri JR1
YP_001615509 289 VYVPEIVSRGLVPDdlgg-yfaQQLKWATGAVDAL 322 Sorangium cellulosum 'So ce 56'
YP_001001804 337 AYINRLSAFGQGPQdlga-yfkQQFRWALGTVGLF 370 Halorhodospira halophila SL1
NP_627065    373 VYTPDVLAVGEGPNawtd-fftQQMRWSRGTYETI 406 Streptomyces coelicolor A3(2)
YP_715141    353 VYTPDVIAVGEGPAtwtd-ffsQQLRWARGANEVL 386 Frankia alni ACN14a
BAB54246     317 VHAMDAIAHGDGPQtfad-lvtQEFQWSRSLMTIL 350 Mesorhizobium loti MAFF303099

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