Conserved Protein Domain Family
GH25_muramidase_2

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cd06419: GH25_muramidase_2 
Uncharacterized bacterial muramidase containing a glycosyl hydrolase family 25 (GH25) catalytic domain. Endo-N-acetylmuramidases are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues.
Statistics
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PSSM-Id: 119381
View PSSM: cd06419
Aligned: 9 rows
Threshold Bit Score: 214.568
Threshold Setting Gi: 58336941
Created: 7-Jul-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
active site
Feature 1:active site [active site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                #                       #                            # #             
NP_784827  49 AVVSGFDVRGVAVSQNDGylDFAALQNDGLKFVYLHATQGASYTDDNFASNYERIVGTSLGVGVIHTFSFSSTAAAQADY 128 Lactobacillus plan...
YP_804117  52 LALAPYPVHGCVIDQENGiiDFNSLQKQHISFVYLNATTGATYFDDSFNTNYSRIQSTDLKVGIVHNFSFQKRPKAQLRF 131 Pediococcus pentos...
YP_396152  46 PNEQQYPVLGAQISQEDGyqDYQILKKESLKFVYLKATEGASYKDDNFDSNYSRAEGSGMSVGVYHFFSFDSSPEDQAQQ 125 Lactobacillus sake...
YP_806308  43 PDPQTYPVLGVRLDQTDGvqDFDSLRSSKVSFVYLKATEGSSYFDDNFNTNFNQAAGSRLSIGIYHVFSFETTPQAQAAQ 122 Lactobacillus case...
YP_818012  48 AIPSGFSVQGVSINQTSNyvDFNNLASNGVSFVYMRTTSGSSVMDGGYKSSFSRAKSAHLKVGTIHVYDASVTAATQAQY 127 Leuconostoc mesent...
YP_810032  92 KANLKKYALGTTLSSDQPytDYSYLKSQNIRFVYFRSTTGNSSFDNLFLTSIKSAKDAGLSVGSMTIYDPSITAYSAYLY 171 Oenococcus oeni PSU-1
YP_795691  49 QQLSNYPIQGVMINQDSGy-LDFQQLANREKFVYLQATSGATYTDDAYGDNFSRSQGADIAVGVVHTFSFTSSAEQQYRH 127 Lactobacillus brev...
YP_193526  38 PPSSNSSAIGIQLNQDVDyvDLHKLQSNGISFVYLKATQGRSYFDENYLSYRDQILGTKLAFGSMITYSNESTPLQHYRY 117 Lactobacillus acid...
NP_964665  38 PRGSNMSVLGIELDQTKDyiDLHKLEKNGISFVYLRSTQGKSYFDDNYLLYRDQIQGTNLNFGTIIAYSDETSNQEQYQY 117 Lactobacillus john...
Feature 1                     # #                                    #                    #   
NP_784827 129 FEKTVGDSIGNLPIAIQVQyygdytdqtiavrksRAKLKALVTTLTQDynrSCVVWSTPAVakqivkp-alkdtdLWLDT 207 Lactobacillus plan...
YP_804117 132 ISQKVKSNTGQLPVVIRVSyygdynakrvdwkkaGPNLADLVKLLANYygqAVVIKTTPAIkrqldpt-yikqskFWLEE 210 Pediococcus pentos...
YP_396152 126 FIKSVGQDTGHLPIMVYLSyyndyaqkppakaktQRAIARFVTLINQYyhqDCIIGGAPALlkryvp--tkgtypLWQTT 203 Lactobacillus sake...
YP_806308 123 FTRQVGQNIGDLPIGIYLSyytekk---pstqwlTTQLQTFVTLVQQHyhrQVLLMGSPSIlkavqk--vdsqapRWVVS 197 Lactobacillus case...
YP_818012 128 YIDNVGNNIGELPIAISVTadqis------tatsKQRLASLVQILASHynhDMIIYTTPNVqkklss--tisktkYWLIE 199 Leuconostoc mesent...
YP_810032 172 FVRKVGKKVGNLPIAVYVTddsit-----ddnsiTNLLGLLQDLKEYYpnnSVIVRCDKTVydevhaklaslnlkYWLIE 246 Oenococcus oeni PSU-1
YP_795691 128 FRATVKEDSGTLPIMVAVAyygkynndnhqmamqGQKLKMLVQKLTQHysqGVIILATHQVldqfvhp-vlpalhYWVAD 206 Lactobacillus brev...
YP_193526 118 FFSQVGNNTGSLPILIEPInsrs--------kkyLRSMGQFTRMLEKHg-kSVIINIDYKYh------------nYFDAQ 176 Lactobacillus acid...
NP_964665 118 FLNKVGTNTGSLPVMIVPAashl-------tksyWKRMGIFAQMINNLg-kRVMIAGDYRYh------------nYFPEG 177 Lactobacillus john...
Feature 1                        #                #    
NP_784827 208 akthq------qgrrVMFMHYSDravyrqngtrqeFAGILF 242 Lactobacillus plantarum WCFS1
YP_804117 211 pqikk------hnwrVQFVEYDAeqkfkndhsdleLPVSYF 245 Pediococcus pentosaceus ATCC 25745
YP_396152 204 qqrpt------vgtkNGFWQYTTaskipggrddseYQLAVF 238 Lactobacillus sakei subsp. sakei 23K
YP_806308 198 dkkp--------ttsSGFWQYTSgarlpn-gphadYRAAVF 229 Lactobacillus casei ATCC 334
YP_818012 200 dntkn------tdskNLFIQYDEdqtigsglkaikMPTTVF 234 Leuconostoc mesenteroides subsp. mesenteroides ATCC 8293
YP_810032 247 nnldg------lgseNQFVQYNAngkvgsgmrsfrLPLSVF 281 Oenococcus oeni PSU-1
YP_795691 207 grltg------qgaqVKFIEYDAngtmtqnaqshaVERAVF 241 Lactobacillus brevis ATCC 367
YP_193526 177 tkfmssdakspnklkYSFWRYTTngrvk---nlagLEKGVT 214 Lactobacillus acidophilus NCFM
NP_964665 178 trflytgaslkdrrhYAFWCYTQngrvk---nidnLERNVT 215 Lactobacillus johnsonii NCC 533

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