Conserved Protein Domain Family
GH25_Lys1-like

?
cd06416: GH25_Lys1-like 
Lys-1 is a lysozyme encoded by the Caenorhabditis elegans lys-1 gene. This gene is one of a several lysozyme genes upregulated upon infection by the Gram-negative bacterial pathogen Serratia marcescens. Lys-1 contains a glycosyl hydrolase family 25 (GH25) catalytic domain. This family also includes Lys-5 from Caenorhabditis elegans.
Statistics
?
PSSM-Id: 119378
View PSSM: cd06416
Aligned: 28 rows
Threshold Bit Score: 181.751
Threshold Setting Gi: 67467471
Created: 30-Aug-2005
Updated: 2-Oct-2020
Structure
?
Aligned Rows:
 
active site
Feature 1:active site [active site]
Evidence:

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Feature 1            #                        #                                 # #              
NP_505642     60 AYAVDISvptt-vsqMNCLKtsRYAAVFIRGFTPFgsg--afDTTSVTSIRNAYSAGLGI-EVYMTPQpls-------sl 128 Caenorhabditis ...
XP_629011     21 HIGIDVSsgtn-esgFECFKqkKYSRAIIRCYESIgs----iDTNCKPSIENAKKAGIETiDVYLFPCydc--------g 87  Dictyostelium d...
XP_001896610  19 GKAIDITtyvd-rsvFRCLFqaGFTIAFIRVYMSNgng--tvDINSASNIYNAASEGMGT-EIYVEPQprg-------tk 87  agent of lympha...
NP_505644     65 AYSVDISfhtt-psdMDCLRdqGYKSVFVRALNPIgnt--yfDRNALNTINNAFEAGLGS-EVYITPNins-------tr 133 nematode
XP_001012588 261 IAFYDLLdye--enmYQCLKfyKVSTQLVDGFKDNtt---ifSPQVQGKIDRAQEQGIST-DLLFDPCvntvrq--enfy 332 Tetrahymena the...
XP_001020047  21 KLGYDISvwegevncFGCTKqsGYDFVVIEIYSSAkq----fNNYLAQNIKSAYNASLEV-DLYIFPDtt---------r 86  Tetrahymena the...
XP_001021822  28 TKLEDVDqfes-idkYICYSnqQFSFQNIVYKQIWg-----yDISHKFGRQYAARTGMKS-NSMYIPCindnpt-kfpfy 99  Tetrahymena the...
XP_001021820  26 FFGFTQNqple-eeeFQCLR--DTTYYFIQTITGN-------DPQTVYQARMASFSGLDT-QLIYIPCinkdtd-sypes 93  Tetrahymena the...
XP_001021821  25 KYSLAFAydke-vgyTDCLKllGMQQQFIHIYKDYg------TINEGFLQLWINKMPFGA-QLVFEPDvdplge--nkya 94  Tetrahymena the...
XP_001597807 111 SLGFDISqlgs-ttfFQCAKk-TKDVVVIRGYEQAcgsggqvDSNFVTSYKNAKAAGFTRiDSYLFPCtgtptgnepqck 188 Sclerotinia scl...
Feature 1                                    # #                                         #       
NP_505642    129 qGYQQLDALYNGlngn---gitIRSVWIQVTs-------pANWqKSATTNVNFLNSIISRAKQY--GLTVGIYTNQYDWS 196 Caenorhabditis ...
XP_629011     88 nPENQVTTTSHYlkdy---lkdLDFLWLDIEgp------gQYWsGSYDNNKKFIQGLLDSAKTAg-FKHVGIYTSESQWP 157 Dictyostelium d...
XP_001896610  88 sGSEQFMEAYTFltkk---giaVRTIWIKITs-------pINWpNNQTANTDFINKFILCAWKH--GLLVGIYTNWYDWE 155 agent of lympha...
NP_505644    134 sGADQISLVYQNllan---ginVRSIWIQVTs-------pTNWvAPMAVRIEFIQDMIRSAKNL--GLSVGIYTSFYDWL 201 nematode
XP_001012588 333 tPEHQVTKFSENykf----ltgYENIWFNVIqka---drnCFWsTDANLNCEILTKYISLLQAQt-GKKIGIRSSSLDWS 404 Tetrahymena the...
XP_001020047  87 dPAEQINSFFQYliane-tmslFNNVWLDIEn-------eNLFfANCTQNIEFLQAMINTTENYisKDRIGLYASQHYWP 158 Tetrahymena the...
XP_001021822 100 tLENQTKNLINFaasyydnrdyGDFFWIVVEann---ikdCQWtNDYQKNCEILTDLVHTASKAsiGLSVGIYSSQEDWI 176 Tetrahymena the...
XP_001021820  94 rVTDQVKTFLKTvhq-----vsCQVIWIQISvnd---dekCKWtDDIDFNCQRTKEIANYLKATa-NKNIGFFSSQEDWI 164 Tetrahymena the...
XP_001021821  95 tPEVEVGQLVQYnpn----ihgYEYIWINVQqrn----kkNQWsTDVEQNCDLLKRFVSLLKSYs-KNKVAVRSSKIDWV 165 Tetrahymena the...
XP_001597807 189 sISTQISEYLQVissn---nmdITMLWLDIEptsastsacNAWnLGAAANEKLAKQWVAAIKAT--GLKWGIYANGNQWS 263 Sclerotinia scl...
Feature 1                             #                                   #            #    
NP_505642    197 QITGnwatl------ssdvLLWYWHvlgggvtGETPATf-DDFRA--FGSFKKASVKQFAQvesvCSLTVNRDVY 262 Caenorhabditis elegans
XP_629011    158 GIVGswdg-------gkdyPIWYAN-------YDGAENf-NDFSP--FNGWTKPHMKQYAGnineCGLGIDKNYW 215 Dictyostelium discoi...
XP_001896610 156 QIIAgqitp-----nqrqiRLWYWNllg-sslNDATPPtfADFRP--FGGFNAPMVKQYAKntpiCGICASLNVY 222 agent of lymphatic f...
NP_505644    202 EITGgwntf------ssdvFLWYWHvlsmgtdGETTPTl-EDFRP--FGPWRQATVKQFGQveklCGMIVNRNVY 267 nematode
XP_001012588 405 NIFGtttnca----nfgnlPLSYIN-------YNQKPNf-QDWQDqqFGSWRGPMMKEFDTte-lCGLTTTLSVY 466 Tetrahymena thermoph...
XP_001020047 159 IMCNttvf--------sdlQLWYPR-------WDNQTNf-NDFTP--FGGFANPVMKQFYNdvqiCCTNTDVDWR 215 Tetrahymena thermoph...
XP_001021822 177 KLFGdsqqcts--nksyatRVHYKS-------YNSQPNf-DDWAEksFGGWAKPHMKTYQNty-vCGSSIDLSVY 240 Tetrahymena thermoph...
XP_001021820 165 KIFGssegcssvsdkknfyPLYYKH-------LDGQPNt-HDYKDhkFGSFENPAMKMYLSte-eCNIKFNANVY 230 Tetrahymena thermoph...
XP_001021821 166 NIFGtsesca----eftdlPLRYIH-------LDSNPNf-NDWPQqsFGQWKQPYMKDYSLas-iCEIDTILTVF 227 Tetrahymena thermoph...
XP_001597807 264 GMFAsrstd-----vgselPLWAVQ-------DDFEAGv-NTVDTf-MGGWTEAVAKQYYLdttlCGLGVDLDSF 324 Sclerotinia scleroti...

| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap