Conserved Protein Domain Family
PB1_Joka2

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cd06398: PB1_Joka2 
The PB1 domain is present in the Nicotiana plumbaginifolia Joka2 protein which interacts with sulfur stress inducible UP9 protein. The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development and cell polarity. A canonical PB1-PB1 interaction, which involves heterodimerization of two PB1 domain, is required for the formation of macromolecular signaling complexes ensuring specificity and fidelity during cellular signaling. The interaction between two PB1 domain depends on the type of PB1. There are three types of PB1 domains: type I which contains an OPCA motif, acidic aminoacid cluster, type II which contains a basic cluster, and type I/II which contains both an OPCA motif and a basic cluster. Interactions of PB1 domains with other protein domains have been described as noncanonical PB1-interactions. The PB1 domain module is conserved in amoebas, fungi, animals, and plants.
Statistics
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PSSM-Id: 99720
View PSSM: cd06398
Aligned: 9 rows
Threshold Bit Score: 116.74
Threshold Setting Gi: 115447045
Created: 27-Feb-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ABF06703       2 IVIKVKYEETLRRFNArvine-kldlNMDGLSDKIFQLFNIardaeLILTYVDEDGDVVTLVDDEDLQDVMRQd------ 74   curled-leaved ...
EAY94534      18 LVVKVKFGGTLKRFTAfvngp-hfdlNLAALRSKIASAFKFnpdteFVLTYTDEDGDVVILDDDSDLCDAAISq------ 90   Indian rice
NP_001047302  21 VVLKVKYGETLKRFGGyvqgp-qfslNLSALRSKIASAFKFgsdvdFILTYTDEDGDIVMLDDDDDLHDAAIHq------ 93   Japanese rice
ABK23785       3 LVVKVKYQGILRRLTLqlreeyvpeiNMDALKCKIRELFKLnpnadMSITYTDEDGDVVTMADDVDFLDAVRQg------ 76   Sitka spruce
EDR14615      15 LIVKCTFDKWHKRITFssa----rncSYDLLRHKVEQCFSLys-tsYAIAYKDDDGEITNITTETDLTEAIQYfqagdda 89   Laccaria bicol...
EAU90259      11 LVVKCTFDKANKKITFnsa----rncSFNVLKEKVEKCFSLr---sSIISWRDDDGETSQIVSDPDLAEAVQYfcsgdds 83   Coprinopsis ci...
CAN77833     192 NGKVVKYGNTLRRFNAcvdengqldlDINGLRAKVITLFNLvpdadLTLTHIDEDGDVVTLVDDEDLHDVMKSlrk---- 267  wine grape
XP_571620     17 LVVRCSYEGSSRRVNFpsa----atcRLESLRNRVEECFSLsa-apYSLIYTDDDGEEFSIRNENDLTEAISYfisgddd 91   Cryptococcus n...
Q9SB64         8 LVVKVSYGGVLRRFRVpvkangqldlEMAGLKEKIAALFNLsadaeLSLTYSDEDGDVVALVDDNDLFDVTNQr------ 81   thale cress
ABF06703      75 ---------------------LNPLRISVRLNAA 87   curled-leaved tobacco
EAY94534      91 --------------------rLNPLRINVELKSS 104  Indian rice
NP_001047302  94 --------------------kLNPLRINVQLNNS 107  Japanese rice
ABK23785      77 ---------------------LNPLRLDVSLATE 89   Sitka spruce
EDR14615      90 plssa----asilsgrsfgprKVTLRVSITVDYD 119  Laccaria bicolor S238N-H82
EAU90259      84 aplssa---asilsgrsfgsrKITLRVTITVDYD 114  Coprinopsis cinerea okayama7#130
CAN77833     268 ------------------kqkPFGHRLDQSVVNC 283  wine grape
XP_571620     92 aatsnysgsvsgvlpyslstsKITLRLDVVVEYD 125  Cryptococcus neoformans var. neoformans JEC21
Q9SB64        82 ---------------------LKFLKINVNAGVS 94   thale cress
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