Conserved Protein Domain Family
monooxygenase_like

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cd06212: monooxygenase_like 
The oxygenase reductase FAD/NADH binding domain acts as part of the multi-component bacterial oxygenases which oxidize hydrocarbons. These flavoprotein monooxygenases use molecular oxygen as a substrate and require reduced FAD. One atom of oxygen is incorportated into the aromatic compond, while the other is used to form a molecule of water. In contrast dioxygenases add both atoms of oxygen to the substrate.
Statistics
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PSSM-Id: 99808
View PSSM: cd06212
Aligned: 10 rows
Threshold Bit Score: 362.804
Threshold Setting Gi: 172068599
Created: 8-Apr-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:FAD binding pocket [chemical binding site]
Evidence:
  • Comment:contacts lie primarily in N-terminal region
  • Comment:based on Acinetobacter sp. Benzoate dioxygenase reductase (1KRH) and Methylococcus capsulatus Methane monooxygenase (1TVC)

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                       #            ####             ### #   ###     
YP_932724 110 FAGKVVGISALTHDIRRLDVELEq--pIRFWAGQFVDITLPEKg-iTRSYSMASVPsspgQVSFIIKKYPNGAFSTALDt 186 Azoarcus sp. BH72
BAD03957  107 VTTKVAAIEPMTPDIVSLKLDVVepesVEFKSGQYFDLFIPGTe-dKRSFSIATTPatpdRLEFLIKKYPGGLFAGMLTd 185 Gordonia sp. TY-5
CAC10508  108 GVGQVVEVEALTHDIRRLELQIEspqgFGFLPGQFVDIWIPGTe-qRRSFSMANLPsd-gRLEFIIKQYPGGRFGALLDd 185 Pseudonocardia sp. K1
NP_770318 109 FTGTVTSVSALTHDIRRLEITLEq--pLKFWAGQYVDITLPGPetiTRSFSMANSPgesqNLAFIIKKYPNGRFSSRLDg 186 Bradyrhizobium jap...
BAF34305  109 GKVQVVANDEVTHDLRRLVVKLIepeeIKFFPGQYMDFIVPGTe-eSRSFSMANTPnregEFEFVIKIYPDGLFSEFLAe 187 Pseudonocardia sp....
AAV52085  111 FAATVDRIDALTHDIRWLGLRLNepetMPFVAGQYVEVGVPGMpdpWRSFSMANSPtesdRVDLIVKVLPGGCFSSVLDq 190 Nocardioides sp. J...
BAF34309  108 AQTTIASVTELTHDIVHVRLALDepsaFRFHPGQYIDIAVPGTd-vSRSFSMACANqadgILDLIIKKYPGGLFSEKLAn 186 Pseudonocardia sp....
BAA07115  106 FQTVVGGVEFLTADIARVRLRLEpgeeIAFTAGQFVNVEVPGTg-lLRTFSLANAPddpsVVELICKLYPDGLFSRFLRd 184 Gordonia rubripert...
YP_481615 108 IESTVVETEDLTHDITRLRLDITgspdFMFHPGQYVDITIPGSs-eHRSFSMANISaaegYLEFIIKKYPGGRFSGLLEd 186 Frankia sp. CcI3
EDT54710  115 FVGEVAAVEALTADIRRLVLTLDr--pMTFFAGQYADITLPDGa-tTRSYSMGNPPrdptRLEFIIKKYEGGRFSSQLDt 191 Methylocella silve...
Feature 1                                       #  #                                          
YP_932724 187 eLKPGDPVLVKGPYGGCFRRee-rpGPMVLIGGGSGMSPLWSILNDHIESGeqRPIRFFYGARTRrDLFYLEQFAEFEq- 264 Azoarcus sp. BH72
BAD03957  186 gLSVGQEIKLNGPYGSCTLRng-hvLPIVAIGGGAGMAPLLSLLRHISETGlnRPVRFYYGARTAaDLFLLDEIATLGe- 263 Gordonia sp. TY-5
CAC10508  186 gLAVGDPVKFTGPYGTCYLRdtggsRSALLIAGGSGMAPILSLLRQMSDDGqgRTVSVFYGGRTRrDLFYTELVQSLGk- 264 Pseudonocardia sp. K1
NP_770318 187 dLAVGTEVGIKGPYGTCFRRen-ktGAMILVGGGSGMSPLWSILHDHISSGevRPVRFFYGARTQnDLFYLDHFAELAa- 264 Bradyrhizobium jap...
BAF34305  188 kVQVGDQLEVEAPFGTFTLRen-rtSDIVFVGGGAGMAPILGLLRSMAERGveRRARFYYGARATrDLCFAEEIAALGeq 266 Pseudonocardia sp....
AAV52085  191 rLSLGDQVQPRGPLGQFGVQls--hRPMIMIAGGSGMAPILGILRELVATGnrREVTFFYGARTAgDLFLVEELGQLAr- 267 Nocardioides sp. J...
BAF34309  187 eLKVGDALTVTGPYGAFTLRvs-sdRRLVFVAGGAGMSALLALLRQMADSGsdREVVYYYGARNEaDLIMTTEIAALAe- 264 Pseudonocardia sp....
BAA07115  185 eAAPGTPVRVFGPYGQLKIRls--hRPILMIAGGSGLAPLLSMLRDLAAKKcdRPVSMFFGARSVdDLYLIEEIREIGe- 261 Gordonia rubripert...
YP_481615 187 gLRPDDPLTVTGPYGAFTLRvs-sdRRIVFIGGGAGMAPILSLLRQLATKNseREVVFYYGARAPrDLFYVDEILQTGa- 264 Frankia sp. CcI3
EDT54710  192 -LAPGAKVTVSGPYGTCFRRehrddSPLLLIGGGSGLAPLLAILEDQIAEApqRSIRLFYGARTQaDLFWQKRFEALEa- 269 Methylocella silve...
Feature 1                                                                                     
YP_932724 265 kVPDFRFIPALSAAepe----dgWTGETGYIHEVVARTLkeegfdgasIDAYTCGPAPMIDAITPVLHMAGVPp-dQMYF 339 Azoarcus sp. BH72
BAD03957  264 kIDDFSFTACLSEStdna--pegVTVIGGNVTDIVNDNEadl----arTEVYFCAPPPMVDAALALAEQHSVPh-dQIFY 336 Gordonia sp. TY-5
CAC10508  265 rIEQFEFIQVVSDEpds----dgDDVRYGFVHDAVDQWIetsgfrldaCDVYMAGPPPMVDAVNDVLTLRHQVeqnRIFV 340 Pseudonocardia sp. K1
NP_770318 265 kHPEFTFVPVLSHAadd----taWGGAKGFVHEAVGEHLrgad-ygedVDVYACGPSPMIEALTPVLQMSDVEs-dRIFF 338 Bradyrhizobium jap...
BAF34305  267 lPSGLTYTPALSHPdd-----epWSGQTGLITEVLQANEstl----egADAYVCGPPPMVDAAIATLTALGVRe-eNIFY 336 Pseudonocardia sp....
AAV52085  268 qHDWFTFIPALSDAgad---gaaWEGETGLITEVLARHLpst----vgREAYLCGPPPMIDAAVEVLESSGCKp-rHIHF 339 Nocardioides sp. J...
BAF34309  265 aLPNFTYVPCLSESwpedwpatfPGGATGLVTEVLLEREpnl----raCDVYLCGPPPMIDAALPVLEGLGVPt-dQVFY 339 Pseudonocardia sp....
BAA07115  262 sLADFEFIPVLSESsp-----adWHGETGMVTDALLRWRae-----laHDVYLCGPPPMIDAAVPLLVERGVRp-rNIYY 330 Gordonia rubripert...
YP_481615 265 sIPGFTFVPCLSDSmpensddigHPVENGLVTDIVDRREtdi----asCDVYLCGPPPMIDAALPRLESSGVPk-eQIFY 339 Frankia sp. CcI3
EDT54710  270 eLPDFRFVPALSAApdd----gqWSGERGFIHEVVQRGLkaeg-igdgADAYACGPPPLIDAVMPVLQMAGVEp-dRIYF 343 Methylocella silve...
Feature 1     # # 
YP_932724 340 DKFT 343 Azoarcus sp. BH72
BAD03957  337 DKFT 340 Gordonia sp. TY-5
CAC10508  341 DKFT 344 Pseudonocardia sp. K1
NP_770318 339 DKFT 342 Bradyrhizobium japonicum USDA 110
BAF34305  337 DKFT 340 Pseudonocardia sp. TY-7
AAV52085  340 DRFV 343 Nocardioides sp. JS614
BAF34309  340 DKFT 343 Pseudonocardia sp. TY-7
BAA07115  331 DAFT 334 Gordonia rubripertincta
YP_481615 340 DKFT 343 Frankia sp. CcI3
EDT54710  344 DKFT 347 Methylocella silvestris BL2

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