Conserved Protein Domain Family
T4MO_e_transfer_like

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cd06190: T4MO_e_transfer_like 
Toluene-4-monoxygenase electron transfer component of Pseudomonas mendocina hydroxylates toluene and forms p-cresol as part of a three component toluene-4-monoxygenase system. Electron transfer is from NADH to an NADH:ferredoxin oxidoreductase (TmoF in P. mendocina) to ferredoxin to an iron-containing oxygenase. TmoF is homologous to other mono- and dioxygenase systems within the ferredoxin reductase family.
Statistics
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PSSM-Id: 99787
View PSSM: cd06190
Aligned: 20 rows
Threshold Bit Score: 262.574
Threshold Setting Gi: 148253128
Created: 21-Feb-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
Feature 1:FAD binding pocket [chemical binding site]
Evidence:
  • Comment:contacts lie primarily in N-terminal region
  • Comment:based on Acinetobacter sp. Benzoate dioxygenase reductase (1KRH) and Methylococcus capsulatus Methane monooxygenase (1TVC)

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                    #            ####             ### #   ###           
Q03304       107 VVSKRFLSDEMFELRLEAEQKVvFSPGQYFMVDVPEL--GTRAYSAANPVDg-NTLTLIVKAVpNGKVSCALAN--ETIE 181 Pseudomonas men...
YP_001237713 111 LRDVVDLAPEVRQFSFETAEPIdFRPGQYAILHLGAD--LRRCYSMSNLPGg-NLLQFIARRYdGGTGSNALAAl-APGA 186 Bradyrhizobium ...
BAC56748     107 VVAVRALTHDLLSVKLRTDVPAnFLPGQFCLIEAEQLpgVVRAYSMANSMNpdGFWEFYIKRVpTGRFSPWLFEnrKVGA 186 Janthinobacteri...
ABF56512     109 LFEINKLTEDMAEFCFKTEHPAhFKAGQFALLDFPGIt-GSRGYSMCNLPNeeGEWRFIIKKMpDGSATTTLFEdyEVGA 187 Cycloclasticus ...
NP_758573    107 VVEVRALTHDLLSVRLRTDGPAnFLPGQFCLVEAEQLpgVVRAYSMANLKNpeGIWEFYIKRVpTGRFSPWLFEnrKEGA 186 Pseudomonas res...
YP_001020118 109 IVAARLLTHDVMSLRIALAAPLsFDAGQFVLVQVPGId-GYRGWSMVNHAKdaLELDFVIKKKpDGKLSDWLFSatPAGT 187 Methylibium pet...
ABK97397     111 LKDFKEVARETITANFYLSGKIsFKAGQYIIVKHPSVe-GYRAYSMTNFEEnsDLLSLVIKNKiNGKLTNYLFDskDDEI 189 uncultured bact...
AAK84310     127 LQNLQRLTRDVICFEIELSEPMdFDAGQFATISLPGLq-GARAYSMVNFVReaRVLEFVVKQKpGGAFSDWLFSttDTSV 205 Marinosulfonomo...
CAA09916     103 VTVKETLCASVIRLVLNVGGPIhFLPGQFFILDLPGA--GRRAYSVANLENaaGGIELLIKRKiGGAGTAALFDqcAPGM 180 Xanthobacter au...
NP_882867    117 LSDVRPLGSGLYRLLADFDDSIrFLPGQYVMLATEAGg-RARAYSVANFAQnsRQLEFILSCNpNGAMSPQLCDinNIGM 195 Bordetella para...
Feature 1                                   #  #                                                 
Q03304       182 TLQLDGPYGLSVLKtadeTQSVFIAGGSGIAPMVSMVNTLIAq--GYEKPITVFYGSRLEA--ELEAAETLFGWKe---- 253 Pseudomonas men...
YP_001237713 187 VITIEAPFGTCTLRrr-pGRKVFVAGGTGIAPILAMMREAAEarlDFGSPVDIIYGARGPA--DLAAHDVLRAVIar-ia 262 Bradyrhizobium ...
BAC56748     187 RLFLTGPMGTSFFRpgtgRKSLCIGGGAGLSYAAAIARASIR---ETDKPVKLFYGSRTPR--DAVRWIDIDIDEd---- 257 Janthinobacteri...
ABF56512     188 EIVIDGPYGLAYLKpeipRDIVCVGGGSGLSPEMSIIKAAARdpqLSDRNIYLFYGGRTPS--DICPPKLIEADDdl-rg 264 Cycloclasticus ...
NP_758573    187 RLFLTGPMGTSFFRpgtgRKSLCIGGGAGLSYAAAIARASMR---ETDKPVKLFYGSRTPR--DAVRWIDIDIDEd---- 257 Pseudomonas res...
YP_001020118 188 AVELFGPLGAATFYpeldKNILCIAGGSGIAGMMSILERAARadyFASHDGDVFFGVRSMK--DAFFLDEFSRLRaacge 265 Methylibium pet...
ABK97397     190 KFDIFGPIGKATFNplerKNLLMIAGGTGIAGLMSILNHADQlryFEDYKVDLFFGVRKYE--DFFFLDEISNLSrkyig 267 uncultured bact...
AAK84310     206 PVSLFGPLDRATFHpeedKNIVMIAGGSGIAGMMSILERASQtnyFRDHKGYVFFGVRTLE--DIFYLEHFVRHVkvagd 283 Marinosulfonomo...
CAA09916     181 GLVIEGPYGRAYLRadsaRGIVAVAGGSGLAPMLSILRGALAr--GFGGPMDLYFGVNTAE--ELFCVPELSALQa---a 253 Xanthobacter au...
NP_882867    196 QLQGYGPLGKAYIRpskdKEIVMLVGGSGVSVALSTLEWAISshyIDDRHLTIFWGVRDTSpiDLIGVLNRYAAVhs-nl 274 Bordetella para...
Feature 1                                                                                     # #
Q03304       254 NLKLINVSSSvvgns-------ekkyPTGYVHEIIPEYmeg-llgAEFYLCGPPQMINSVQKLLMIENkvpfEAIHFDRF 325 Pseudomonas men...
YP_001237713 263 QARYLPVVENapsg---------wphAAGFVTDAIKATipd-paaAEFYVAGPPIMVDAVKSLLRSADvp-iTQVHYDSF 331 Bradyrhizobium ...
BAC56748     258 KLEVVQAVTEdtds--------lwqgPIGFIHQVVDAAlletlpeYEIYLAGPPPMVDATVRMLLGKGvp-rDQIHFDAF 328 Janthinobacteri...
ABF56512     265 RVKNFNAVSDveaaea-----agwngDVGFIHELLGKTlgeklpeHEFYFCGPPPMTDALTRMLMTEYkvpfDQIHYDRF 339 Cycloclasticus ...
NP_758573    258 KLEVVQAVTEdtds--------lwqgPTGFIHQVVDAAlletlpeYEIYLAGPPPMVDATVRMLLGKGvp-rDQIHFDAF 328 Pseudomonas res...
YP_001020118 266 RLRVTIAFSEepasdalrashpllqfETGFVHEVAGRGmqgryqgVRAYLAGPPPAVDACVRMLLMARvs-tDNIRYDKF 344 Methylibium pet...
ABK97397     268 NFNIYFITSDekvssk----inscdvSNGFVHEVFEDNlksdyseRIAFLGGPSRMIDLLIPTLLKIGvs-hDCIRYDKF 342 uncultured bact...
AAK84310     284 NLHVTLAISDsevadgphpeqscvnlASGWVHEVAGKVmtgqyddVLAYVAGPPPMVDGAIRTLTMEGclnpQFIRYDKF 363 Marinosulfonomo...
CAA09916     254 GARVHLALRDggpgp------aglhrQAGLIGDALVAGepd-lkaKDLYVAGPAPMTDDILARTVRQEaipaDRVFFDRF 326 Xanthobacter au...
NP_882867    275 QVAVCSDISPsvqdrar---fphvefFKGYPADHIVNDasirwedKEVYISGPPPMVDHTVRQLMINTeidaQDIKCDSF 351 Bordetella para...
Feature 1         
Q03304       326 F 326 Pseudomonas mendocina
YP_001237713 332 G 332 Bradyrhizobium sp. BTAi1
BAC56748     329 F 329 Janthinobacterium sp. J3
ABF56512     340 Y 340 Cycloclasticus sp. P1
NP_758573    329 F 329 Pseudomonas resinovorans
YP_001020118 345 S 345 Methylibium petroleiphilum PM1
ABK97397     343 G 343 uncultured bacterium Sargasso-2222818
AAK84310     364 G 364 Marinosulfonomonas methylotropha
CAA09916     327 V 327 Xanthobacter autotrophicus Py2
NP_882867    352 V 352 Bordetella parapertussis 12822

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