Conserved Protein Domain Family
PurM-like1

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cd06061: PurM-like1 
AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two conserved domains and seem to dimerize. The N-terminal domain forms the dimer interface and is a putative ATP binding domain.
Statistics
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PSSM-Id: 100037
View PSSM: cd06061
Aligned: 43 rows
Threshold Bit Score: 285.259
Threshold Setting Gi: 160878308
Created: 4-Jun-2007
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
putative ATPdimerization
Feature 1:putative ATP binding site [chemical binding site]
Evidence:

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                                                        
ZP_01574817    2 EPGKLPNDILNKIVFGKIntfrkevimrpg-----------------------igedcaaiefdkYACVMSTDPITaa-- 56  Clostridium cel...
YP_001557276   2 KTGKVSEVILKRSVLKFLgtkqrntp-------------------------------visldagkIEFDESTDLLFatas 50  Clostridium phy...
ZP_02026508    2 NPGKVSEVTYKRAILKNLnsknegvkpg---------------------------vnaaniqledITAVVSSNCILkt-- 52  Eubacterium ven...
ZP_02205984    1 MRGKFGEHQTVRSILKSLphtvhddvtragigedyarlllrdgdggentgktgdadcknagaaksKSVNVATGVCIds-- 78  Coprococcus eut...
ZP_02074543    2 NKEKFRFIQQKRSILRSLnkqehsditqag-----------------------igddysrlvlldSELAVTEGLCLan-- 56  Clostridium sp....
BAD85150       3 PPGKLRNDILREVVFPNLgvedskvvygpre----------------------gfdsavleyddeHYLVVATDPTLgvp- 59  Thermococcus ko...
NP_279302      2 DDGKAGRGFFDDHIAGRTgadrddvrlgpt-----------------------ygadfgvvaiadSVVAMATDPVFvlra 58  Halobacterium s...
ZP_01718431    3 DLGKINHEGYQSLLAGRLgafrkevkqgpgf----------------------gvdvaitslpggLAMAATSDPLSlips 60  Algoriphagus sp...
YP_429559      1 MIGKVDDAFFRQAILPHTgagdpevvvgpr-----------------------mgvdaavlkigeEYLAVAEDPIFpgpt 57  Moorella thermo...
YP_064233      6 LVGKPSPSRLQALVQGALgkpcksllvgpgp----------------------gldaailqtadgRVMAIAEDPIFpapg 63  Desulfotalea ps...
Feature 1                          #                                             ###             
ZP_01574817   57 ----gkNAGRLAVHISCNDIASSGVEPLGLMVTILCpvgttETELEHLMDQVCETAGQLNVEIIGGHTEVTPAVnk-iiL 131 Clostridium cel...
YP_001557276  51 mqgnqfGLIESVFHRAVNNIYAKGGKPIAVSTSLTLrshadEQELKLYSKELNRLSTLYSIPVLSGETMVGAGAtq-ntI 129 Clostridium phy...
ZP_02026508   53 ----fdGCEEFYVQRSINSICEKGGVPKSLQLSITMplefeEKEVNRMIKNFRKSADSHNVEINQCNVYRGTTEgp--iI 126 Eubacterium ven...
ZP_02205984   79 ----gyMGLRLDIARLYNSVRIGGYMPWVATDTIVMpd-ddERRMKKLLGKLAGICAECGVDIITGHTEVNTAVfe-piI 152 Coprococcus eut...
ZP_02074543   57 ----alGTVTSDVIKQYNKLRLGGYQPFALTDTVMMpe-ndEKRMKKILRELSDLAKEFHMDVVYGDTAISGIFke-paV 130 Clostridium sp....
BAD85150      60 ----eeTFGFFTYHFASSDVAVFGARPRWLVVDLLFpegtsREFLEATMKDLNAECRKYGSAIVGGHTGVYPSIse-ptA 134 Thermococcus ko...
NP_279302     59 --lgieRAAWFAFHICVSDVALSGLSPAHLAVDLNLppdtaTETFDAIWEVFDREARALGVSLTTGHTGTYEGCsfptvG 136 Halobacterium s...
ZP_01718431   61 --lglqESAWLSVHLMANDMATTGFAPQYGQFVLNLpdslsNADFSTYWGYIDRFCKEIGVAITGGHTGFVQGQnstfaG 138 Algoriphagus sp...
YP_429559     58 --tspdDFGWITVHIGASDVAVMGIKPRFMTYSLLLppgtpEDYIAGLVRSISTYARELGITIVGGHTGFYGAVtiptiG 135 Moorella thermo...
YP_064233     64 --lpldIMGWFTVHIGASDIAVTGVKPEFMTYTLLLplgcpEEDARTIISSISRAAEDLGISIVGGHTGWYGAVtvptvG 141 Desulfotalea ps...
Feature 1                                                                                        
ZP_01574817  132 STTCVGKSLKDkiisss------gakpgDSVILTKSAGLEGTAIIAGDFEEElAEVMNKNELQYAKSLINAis-vVPEGV 204 Clostridium cel...
YP_001557276 130 TIHATGKVNKQsntmdkkqesiedsakeYQIVMSKYIGLSATKLLIESRKEKlKERLTESFLAGGKKIGELls-iQKEME 208 Clostridium phy...
ZP_02026508  127 NIFMIGTTGNLlksds--------ikpgMDVIMAGTLAIGGTSVIAERYKDKlEGKFSGRFISECLELKDYts-tEKASA 197 Eubacterium ven...
ZP_02205984  153 SVTMMGKQSGHsddadlc---rlkrpvgMDIVMCGQTGVGGTLQLYYDNQKElFERYSESYLRPVERMEELil-lGRQVD 228 Coprococcus eut...
ZP_02074543  131 TVTMYGRRISQgekna-------kikpdMDIVMCGQAGILGTLLRVRERKEElLTRYSEEYLRTAEQFDRLl--lVKDQG 201 Clostridium sp....
BAD85150     135 TTTAMGIVRKGelklp-------lakpgDKIVVTAKVGLEFAVSAAYFRADElSKVLTKKELMRLKRSFYFet-aVPDAL 206 Thermococcus ko...
NP_279302    137 GATALAVGAAEdvvtpt------gaqpgDRVVVTKGPAVETTGMLGVLFGDRlPISAAAAAAARDRFADATp---VRDAA 207 Halobacterium s...
ZP_01718431  139 GGTLITIAPESemicat------gaeegDVILVTKSCAMTATAILGMSFPETvKNKLGTDVYESACQQFYQts-sLKDGL 211 Algoriphagus sp...
YP_429559    136 GITVWGRGREVvtpag--------arvgDAVIITKGAAIEAAALVACELGEKlLAAGISPDLVARAKKRLRemsvVAEAG 207 Moorella thermo...
YP_064233    142 GVTVWGTADQDawispg------gakdgDLILMTKGPCIEAAALLSIVHHERlQGNISEEMLATLRARVDQit-vVEDAL 214 Desulfotalea ps...
Feature 1                                                                                        
ZP_01574817  205 Lagrf-----gvtSMHDITEGGVLgaAWEIAeasSTGVTIKKDSIPVEPVTRHICDHFGINPLRLISSGCMIITCkd--g 277 Clostridium cel...
YP_001557276 209 Vstdf-----dilCSHDVSEGGIFaaLWEVGeslQCGMEVSLDSILLIQETIEVCETLDLNPYLLYSGGCVLFVTkq--g 281 Clostridium phy...
ZP_02026508  198 Iaida-----gavYMHAVSEGGLFsgLWEVAscvDKGIQVDINKIPIWQQVIEIAEFMDINPYLLEGSGSLLIVSpd--g 270 Eubacterium ven...
ZP_02205984  229 Ialeh-----gsvYAHDISRGGVFaaLWEMGdalKCGLEVCHDDIPILQETIEICEHTGDNPYMIDGCGAALFVVpd--g 301 Coprococcus eut...
ZP_02074543  202 Diamac---gsiyVRHISTEGVYGa-LWELAeagNVGLRISHDHIPIMQETIEICEFTGDDPYRIDGCGAALFVTad--g 275 Clostridium sp....
BAD85150     207 Vakp------fvrGMHDATEGGLTa-LHEIAdnsGVGFRVYSDRLHIDPLVKKVLDFYDLKPWSVSSTGTLIAITptekv 279 Thermococcus ko...
NP_279302    208 Tmaaa----gevtAMHDATERGLAngLHELAaasGVGLSVARDAVPVLPGVRAVCEQFGMDAWAASSEGTVIAAVdpgsv 283 Halobacterium s...
ZP_01718431  212 IaagesekfpeitAMHDVTEGGVLgaIYEMLiasGKGGMIENDLIPVGEIASQISKLFDLDPRYCVGAGAMIISCrpdks 291 Algoriphagus sp...
YP_429559    208 Iavev----ggvhAMHDATEGGLArgLWEVAeasGVGLRIERARVPVPADIRAVCDYIGLNPYEVISEGTLVLTCapeka 283 Moorella thermo...
YP_064233    215 Hafkv----ggvhAMHDATEGGVQggLWEMStssGLPVMVDFDGVEIPADIVALARELDFDPWQAISEGTLLAAVepeqv 290 Desulfotalea ps...
Feature 1                            
ZP_01574817  278 EGLVRLLgenniKASIIGTI 297 Clostridium cellulolyticum H10
YP_001557276 282 EALVEKLnnegiPASVIGKT 301 Clostridium phytofermentans ISDg
ZP_02026508  271 YKIEESLnangiYGEVIGKI 290 Eubacterium ventriosum ATCC 27560
ZP_02205984  302 EHLADKLyeagyEASVIGHL 321 Coprococcus eutactus ATCC 27759
ZP_02074543  276 GLLSDRLyeagfEAAVIGRT 295 Clostridium sp. L2-50
BAD85150     280 NSLITELlkngiLAFELGEF 299 Thermococcus kodakarensis KOD1
NP_279302    284 DAVLGALgdegiPAADVGVV 303 Halobacterium salinarum NRC-1
ZP_01718431  292 AQLIDRLgneniSCTVVGKV 311 Algoriphagus sp. PR1
YP_429559    284 DAMLAAFkeagiEAAVIGRV 303 Moorella thermoacetica ATCC 39073
YP_064233    291 QEVQRVWadlgiDSYILGKF 310 Desulfotalea psychrophila LSv54

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