Conserved Protein Domain Family
R3H_unknown_2

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cd06006: R3H_unknown_2 
R3H domain of a group of fungal proteins with unknown function. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. The function of the domain is predicted to bind ssDNA or ssRNA in a sequence-specific manner.
Statistics
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PSSM-Id: 100076
View PSSM: cd06006
Aligned: 13 rows
Threshold Bit Score: 95.5152
Threshold Setting Gi: 49654083
Created: 27-Feb-2008
Updated: 2-Oct-2020
Structure
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Aligned Rows:
 
RxxxH motif
Feature 1:RxxxH motif
Evidence:
  • Comment:The RxxxH motif gives R3H domain its name.
  • Citation:PMID 9787637

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                   #   #                         
XP_449648     745 CTDIENTLNKLIDDnn-------------rTSLHFKPmRPPQRYFIRELAKAYnLYSESQDPePNRSVFVKK 803  Candida glabrata CBS 138
XP_001646152  748 CNQIEELINKFVNDkn-------------kPSLHFKPmPAPQRNFIHALVEAYeMYSESQDRePKRSVYLKK 806  Vanderwaltozyma polys...
CAG86499      739 CARIESTLRDFIVGyqnnnseiegalafdkRLRQFPPmTTPQRAFIEDLASSYkLYTEQQDSgSNQSIFVVI 810  Debaryomyces hansenii...
AAS51707      688 CTQIEQYLIKLMDDss-------------pKALHFKPmRAAQRRFVHELSSSFgLYSESQDPePKRSVYVKK 746  Ashbya gossypii ATCC ...
EAT88804       96 AATQEKQLRLFAADpe-------------aKRFRFKPmQRHQRAFVHSLAEDFgFDTESMDPePHRHVAIFK 154  Phaeosphaeria nodorum...
XP_454325     707 CDQICAVFDKFIEDtq-------------kLSLHLKPmRVPQRQFIKELASAYaLYSESQDRePNRSVYLKK 765  Kluyveromyces lactis ...
CAG80840      737 CIEMEQKIAALVNDes-------------kKVLRFPPmHTAQRAFLHQLAEVYgFTSISQDPePYRSVSIMQ 795  Yarrowia lipolytica C...
P53971        736 CSQIEAILNKLMDDkt-------------rSSLHFKPmRPPQRHFIRELAKAYgLYSESQDRePMRSVFIKK 794  baker's yeast
XP_001527559  760 CSKVEDTIRSFINDynaqien---gvespkRSFHFTAmTSPQRQFVHELGKLFgLYTESQDAePKRATFIVI 828  Lodderomyces elongisp...
BAE55272      599 LQSYESTLHSLAANpt-------------qRSVRFQPaKSSLRAFVHSLATDWgFASESFDPePHRHVFVLK 657  Aspergillus oryzae
CAA21417      838 ADEVESLLRNFVNNk--------------aSSFRFPSmRREQRAFVHMFAKLLgLESVSFDPePKRNVMVYN 895  fission yeast
XP_001241868  122 LQGYEASLHALATQds-------------qKSNRFPPcRSQLRAFIHSLAGDWgFQSESFDPePVRHVFVYK 180  Coccidioides immitis RS
XP_001541140  846 LQTYETTFYTLATSqt-------------kRSARFPPaRSQLRAFIHSLAADWgFISESYDPePHRHVAVFK 904  Ajellomyces capsulatu...

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